Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> On Treatment -> Does this mean I'm allergic to S/O?
Post Info TOPIC: Does this mean I'm allergic to S/O?
RudiRoo


Senior Member

Status: Offline
Posts: 158
Date:
Does this mean I'm allergic to S/O?
Permalink  
 

skewedButNotBroken wrote:

I just finished this treatment a few weeks ago and my numbers are:

 

Eosinophils: 6.3%

Basophils 0.5%

Bilirubin Total 0.6

 Thanks - those are some reassuring numbers. Hope you get to add those three happy little letters to them soon! 



-- Edited by RudiRoo on Friday 14th of November 2014 02:10:07 PM

__________________

Hep C since 1982, GT IL28b CC, tx naive, VL 2.5M, normal liver panel, Hepascore F-0, A-1. Sjogren's, Hashimoto's, Raynaud's, etc. SOT S/O 12 wk tx on 10.28.14. EOT 1.19.15. HEP C FREE AT LAST! 4.29.15
skewedButNotBroken


Senior Member

Status: Offline
Posts: 189
Date:
Permalink  
 

I just finished this treatment a few weeks ago and my numbers are:

 

Eosinophils: 6.3%

Basophils 0.5%

Bilirubin Total 0.6



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!
Groupergetter


Guru

Status: Offline
Posts: 796
Date:
Permalink  
 

Hey Gman, thanks for hanging out with us wannabee's.  biggrin  

And Rudi, you're gonna find SVR before you know it. smile   Loved your picture perfect island view. 

Must be nice smile

 

oops

-- Edited by Groupergetter on Thursday 13th of November 2014 11:45:57 PM



-- Edited by Groupergetter on Thursday 13th of November 2014 11:48:01 PM

__________________

1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
Tig


Admin

Status: Offline
Posts: 9284
Date:
Permalink  
 

Hey Rudi,

You pretty much hit it on the head, it's due to your immune system going full Rambo on the virus! Not to worry at all, they will do a lot of fluctuating and as long as you're getting weekly labs, your doctor will have an alert eye on all of that? Good luck Roo...

Tig

PS: Love 1st Class!



__________________

Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
RudiRoo


Senior Member

Status: Offline
Posts: 158
Date:
Permalink  
 

Thanks everyone! My doctor called and said my labs were great.  I'm doing labs weekly because I never want to wind up in the very scary hospital here. Still wondering what makes the eosinophils & basophils go up - not worried, just curious. Is that my immune system on full Rambo?

Thanks for the laugh Gator Man! Some of us are cruising first class and some of us are bumping along in the box cars. Last stop is still SVRVILLE!

firstclass.JPG



Attachments
__________________

Hep C since 1982, GT IL28b CC, tx naive, VL 2.5M, normal liver panel, Hepascore F-0, A-1. Sjogren's, Hashimoto's, Raynaud's, etc. SOT S/O 12 wk tx on 10.28.14. EOT 1.19.15. HEP C FREE AT LAST! 4.29.15
Fireman Rob


Senior Member

Status: Offline
Posts: 334
Date:
Permalink  
 

Rudi,

I had similar blood results. My doc wasn't concerned about it one bit. My bili spike towards the middle of Tx.

Good luck!

-Rob



__________________

Age 33, Male. GT-1 for ten years. Diagnosed in March, 2014.

Treated with Sovaldi/Olysio: SVR 24 on February 16, 2015!
Sierrajen


Veteran Member

Status: Offline
Posts: 71
Date:
Permalink  
 

Thanks for making me laugh Gator Man. XD

 

 



__________________

Gen 1a -  treatment naive  HepC since mid 70's

started Harvoni 11-06-2014   for 12 weeks

13,000,000 VL to 50 VL in just 4 weeks- 

Post TX Labs 5/5/15 Undetected! CURED!!

 
Isiscat2011


Guru

Status: Offline
Posts: 1724
Date:
Permalink  
 

hehehehe.....the Master has Spoken!!



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Gator Man


Senior Member

Status: Offline
Posts: 442
Date:
Permalink  
 

Isiscat2011 wrote:
Gator Man wrote:

 

S/O may be old stuff with Harvoni available to fortunate people today, but it worked for me.

 

Yes, S/O is so YESTERDAY! biggrin    Now we will become HCV tx snobs.  

 

 

images?q=tbn:ANd9GcRPPeBQ9tNn5hglxeFlrDmwlcIq05bRRCH28pSDdYqCBxa77YRX

 

I don't usually take cutting edge HCV drugs, but when I do, its Harvoni.

 

 



__________________

Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
Isiscat2011


Guru

Status: Offline
Posts: 1724
Date:
Permalink  
 

Hi RudiRoo:

I wasn't on this combo but from everything I have read and heard this is not unusual and certainly would not indicate an allergic reaction.  Olysio is absorbed at varying rates in different people and has been known to can effect bilirubin levels in particular.  I would just keep a close eye on this for the time being.  Maybe blood test a bit more frequently until your doc is sure all is well.  



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Isiscat2011


Guru

Status: Offline
Posts: 1724
Date:
Permalink  
 

Gator Man wrote:

 

S/O may be old stuff with Harvoni available to fortunate people today, but it worked for me.

 

Yes, S/O is so YESTERDAY! biggrin    Now we will become HCV tx snobs.  

I admit I have a preference for the "nuc" and only Gilead makes it.  I guess that makes me a tx snob too.

Whatever you pair up the nuc with it should be good.  At least from what we know now.  In 5 years I could be eating my words.  



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Gator Man


Senior Member

Status: Offline
Posts: 442
Date:
Permalink  
 

I had a mild increase in bilirubin to 1.5 and a slight increase in part of my differential count, although I don't recall which cells. My doctor wasn't concerned and said this was quite normal, particularly with Olysio and your bilirubin will spike and then decline during Tx. Everything has returned to the normal range, and my bilirubin is at .9 at EOT +26 weeks. I think the rest of your symptoms are not unusual either, but I would certainly inform your doctor at the next exam or earlier if they get more pronounced.

S/O may be old stuff with Harvoni available to fortunate people today, but it worked for me.

Good luck and keep us posted!

 



__________________

Geno 1b, compensated cirrhotic, 54 yo, prior null responder. Pre tx VL approx 595,000, tx with Sovaldi/Olysio (no Riba) started 1/8/14. VL 40 @ 2 weeks, UND @ 4 weeks. Still UND @ EOT + 1 year.

Gator Man SVR12, Dragon 0, Final Score.
LC


Senior Member

Status: Offline
Posts: 473
Date:
Permalink  
 

I think it's common for bilirubin to go up doing treatment as the meds flush out the virus. I believe the other two are white blood cells, so their increase should be a good thing. It sounds like it's fighting the virus and all, but I don't really know.

__________________

Genotype 1a, VL 1,151,923.  51 years old.  Started treatment on AbbVie TOPAZ II clinical trial Oct 10, 2014!  Undetected at weeks 2 and 4! 
RudiRoo


Senior Member

Status: Offline
Posts: 158
Date:
Permalink  
 

Got my two week labs back and my Eosinophils were 6% (0-4 normal) and Basophils 3% (0-3 normal) were high.

Is this an allergy? Also my bilirubin went from .05 to 1.0 which is the highest normal value. 

I can't find this on either Sovaldi or Olysio's prescribing info and I don't know what it means. I've been tired and nauseaus but no rash. Mild intermittent itching and brain fog also. No rash or other allergy signs.

Wondering if someone can tell me what this means?



__________________

Hep C since 1982, GT IL28b CC, tx naive, VL 2.5M, normal liver panel, Hepascore F-0, A-1. Sjogren's, Hashimoto's, Raynaud's, etc. SOT S/O 12 wk tx on 10.28.14. EOT 1.19.15. HEP C FREE AT LAST! 4.29.15
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> On Treatment -> Does this mean I'm allergic to S/O?
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.