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Hep C Discussion Forum -> General Discussion -> Viekira Pak...Informative power point
Post Info TOPIC: Viekira Pak...Informative power point
maddie


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RE: Viekira Pak...Informative power point
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Interesting point.  Thanks Mallani!



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
mallani


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Hi Maddie,

Good info. It should be pointed out that 'treatment- experienced' refers to Peg/Riba only, not to previous antiprotease failure. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Tig


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Thanks Maddie, that was very informative! I liked the breakdown of all the associated studies and their success rates, that's helpful. I had trouble opening it with Chrome on this iPad but Safari opened it right up. 

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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maddie


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This power point is quite informative as to all the studies done leading up to approval of drugs.   The contraindicated medications when on the Viekira protocol are listed on slide 7

http://depts.washington.edu/hepstudy/presentations/uploads/131/3d__master.pdf



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Dx. 2005-liver bx.: stg 2/gr 1. at that time  - GT 1a multiple transfusions in 1981.  Started Sovaldi and Olysio 1/16/14  (No prior treatments) Q80K present.  UND week 4,8 and at EOT.   UND at wk 4EOT, Und at wk 8EOT  SVR 12!!!..SVR 24 :-)
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