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Post Info TOPIC: Went up abit but how is my 5 month on harvoni look to you guys?


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RE: Went up abit but how is my 5 month on harvoni look to you guys?
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MM,

Lab normal ranges for ALT can vary. Many Labs use 10-40 U/L, some use 7-56. John's Lab is using <63.

The GGT is not a good indicator, and should be ignored. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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I will tell ALT goes up a little bit last month and standard range less then 63 U/L is wrong as I know... Normal range for males is 10-40 U/L.

Do you take any antibiotics now, aspirin? Did you get sick recently (cold, fever and etc...) and took any medicine?

John, can you show us the trend of your GGT, please?

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G1b, stage 4, cirrhosis

Harvoni Tx: Jan-Jun 2015 for 24 wks, SVR12, SVR24

PrevTx : relapser, Sovaldi +Peg+Riba for 12 wks, Jun-Sep 2014

My thread



Guru

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No big deal John.

Keep trucking- you' ve got this at last.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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ast went up from 32 to 35  :  normal is less than 34 :  no big deal?



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 



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Hi John, all looks fine to me, you`re on track and doing well.

Not much longer now...well done!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Looking good John.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm

Tig


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Hi John,

Those are good numbers! Everything is dialed in pretty well. The bilirubin is fluctuating very slightly and that's nothing to worry about IMO. We see that happen on your protocol frequently. So glad to hear you tested undetectable so fast. That's a good sign that everything is headed in the right direction. Keep it up!

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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NEUTROPHILS %, AUTOMATED COUNT42.0 - 75.0 %57.2
LYMPHOCYTES %, AUTOMATED COUNT20.0 - 51.0 %27.2
MONOS %, AUTO1.0 - 12.0 %10.6
EOSINOPHILS %, AUTOMATED COUNT0.0 - 10.0 %4.1
BASOPHILS %, AUTOMATED COUNT0.0 - 1.0 %0.9
RBC NUCLEATED AUTO COUNT, BLD<=0.0 %0.1
NEUTROPHILS, ABSOLUTE, AUTOMATED COUNT1.8 - 7.7 x1000/mcL2.4
LYMPHOCYTES, AUTOMATED COUNT1.2 - 3.4 x1000/mcL1.1
MONOCYTES, AUTOMATED COUNT0.1 - 1.0 x1000/mcL0.4
EOSINOPHILS, AUTOMATED COUNT0.0 - 0.7 x1000/mcL0.2
BASOPHILS, AUTOMATED COUNT0.0 - 0.2 x1000/mcL0.0


__________________

John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 



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Name
Standard range
   11/14/1412/3/1412/16/141/15/152/11/153/10/154/7/15 
ALKALINE PHOSPHATASE
<=125 U/L
   2111631541101109590 
ALT
<=63 U/L
   129786260573748 
BILIRUBIN, TOTAL
<=1.0 mg/dL
   0.71.61.41.21.60.81.1


__________________

John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 

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