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Hep C Discussion Forum -> On Treatment -> 4 week labs on Viekira + Riba
Post Info TOPIC: 4 week labs on Viekira + Riba
Tig


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RE: 4 week labs on Viekira + Riba
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Hey Mona,

While it's nice to see an undetected result at 4 weeks, it's not unusual to have to wait until week 6-8. Some just take longer and as Gracie mentioned, some doctors won't do a VL until EOT+12 because it's so uncommon to finish treatment and not be undetected. It just happens, so I would concentrate on the excellent result given. Your viral load has taken a huge drop and that's a sure sign the drugs are putting their whammy on your Dragon! You'll be undetected soon, I'm sure of it.

If you would like, it would be helpful if you added your genotype to your signature line. 1A or 1B?



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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Hi Mona, I went to your bio page and dont see what geno type you are? If your a 1-b you need not worry.  1-b has a VERY high svr.    1-a  is a little tougher to treat  so riba  can be added.  Stay with it.   RC



-- Edited by robertsamx on Saturday 27th of June 2015 08:30:01 PM

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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
zavr


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Hi Mona,

That sounds very frustrating. If it helps, I was on VP (no RIBA), and was still detectable at 4 weeks, but undetectable at 8 weeks. Keep going!



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Gen 1b, 33yo. Started 12wk Viekira Pak on 2/28/2015. 

Baseline: VL=517K, AST=34, ALT=56. 

Wk4: VL=<15, AST=16, ALT=14.

Wk8: VL=UND, AST=17, ALT=14.

Wk12: VL=UND, Fibroscan: 3.4kPa, F0.

--->Viekira Pak financial and nurse support<---
Gracie


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I asked her for a test during treatment for my own sanity, and she said yes, but not until after 8 weeks. For some it takes a bit longer to clear, but has no effect on outcome. These are very successful regimes. Us previous treatment failures will worry though, but statistics and results are very high on our side. 

How have you been feeling? Any side effects? 



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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.
Mona


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Gracie, Thanks for the encouragement. I'll take your advice and just stay focused. I'm one third through! All the best to you.



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healthcare worker exposed to Hep non-a non-b in 80's. found positive when donating blood. Non-responder to peginterferon and riba in 2009 after 12 weeks. started Viekira pak and Riba on May 25, 2015.  F2, no cirrhosis.
Gracie


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Hi Mona,

No worries... There have been a few who took a bit longer to clear. My hepologist doesn't even recommend a blood test until 12 weeks post as the other tests don't matter one bit. You'll clear, just stay on track! 



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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.
Mona


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I just got my 4 week lab results.

HCV RNA PCR QT (IU/ML) is 97    Reference <15

HCV RNA PCR QT (LOG IU/ML) is 1.99   Reference <1.18

This makes me nervous. Has anyone else NOT been undetectable at 4 weeks and still go on to be Undetectable?

Taking exactly as I should. With food twice a day within the same time frame morning and night, haven't had a drop of alcohol in years. No other meds.

Just wondering if anyone has had same experience? Thanks.



__________________

healthcare worker exposed to Hep non-a non-b in 80's. found positive when donating blood. Non-responder to peginterferon and riba in 2009 after 12 weeks. started Viekira pak and Riba on May 25, 2015.  F2, no cirrhosis.
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