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Hep C Discussion Forum -> On Treatment -> Genotype 3 treatment progress
Post Info TOPIC: Genotype 3 treatment progress
Tig


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RE: Genotype 3 treatment progress
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Mavyret safe, effective for HCV genotype 3 regardless of cirrhosis

 

Wyles D, et al. Hepatol. 2017;doi:10.1002/hep.29541.

September 25, 2017

Patients with hepatitis C genotype 3, with or without compensated cirrhosis, achieved significantly high rates of sustained virologic response after treatment with Mavyret and experienced no significant adverse events related to the drug, according to recently published data from a phase 3 study.



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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robertsamx


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Hi John, Hows it been going? Is the sleep issue geting any better?Hope your doing well!  RC



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
wmlj1960


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Hi John.

 I'm glad you are not having side effect other than insomnia. When I treated with 24 weeks Sovaldi / Ribavirin last year I also felt like I had more energy soon after starting treatment. I even painted the house I was renting and paid for the paint myself just to have something constructive to spend my energy on. biggrin

 Monthly bloodwork is a good plan and hopefully anemia won't be a major issue with you. I stayed on my full dose of 1000mg / day Ribavirin throughout treatment, and that included going through a traumatic accident and 4 major surgery's at week 15 thru 24, then another major surgery 2 weeks post EOT. My CD4 and HIV viral load were trashed during it all but that was probably due more to the surgery's rather than the Sovaldi or Ribavirin.

I would also be interested in knowing your lab results as you progress through treatment since we don't see many being treated with Daclynza. And I'm especially interested also since we don't have many co-infected members either. 

Good luck with your treatment and yes I'm looking for that light at the end of the tunnel too. smile

 

 



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60 yo, geno 1a, Dx 1994 HCV-HIV co-inf, Dx 2013 decompensated cirrhosis
Tx #1 - 24wks Sov+Riba /SOT 7-24-2014/UND@EOT/DETECTED@EOT+16 wks
Tx #2 - 24wks Harvoni /SOT 7-25-2015/UND@EOT,+12,+24,+52 = SVR

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robertsamx


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Hi John, I"m glade to see your doing so well. That new found energy  might be the riba buzz! It sounds like your Hg  is good. Your one tough guy to go on vacation while on treatment, my hats off to you!!  Like Tig has mentioned, we would be interested in a more in-depth look at your treatment and blood work results. Type 3"s  treatments are just now really geting traction, any your treatment combo is cutting edge stuff  (IMO)     RC

 

 



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Tig


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Hi JB,

I wish I could do some of the traveling you're doing! Enjoy your time, it goes by pretty quick sometimes.

Sounds like your treatment has been fairly easy on you. No comparison to the old stuff huh? Thats great. We don't have many people here that have had the opportunity to try the Daklinza combos. If you have time someday, start a separate post and share some of your thoughts and experiences with the combo, it would be helpful.

Congrats on your undetected results! You're on your way buddy! WOOT!  



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Cinnamon Girl


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Hi Jake, welcome back!  Hope you enjoyed your trip!

Sounds like you`re sailing through your treatment with your new found energy, what a wonderful feeling that must be!  I remember you weren`t sure whether to take your vacation while on tx or defer it until afterwards, and seems like you made the right decision to go ahead.

Congratulations on your 8 week undetectable result, what a boost! 

Thanks for your very positive update, do keep us posted on your progress!  Onwards and upwards! smile

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
JakeAms


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Hi all, I have been traveling for the past 6 weeks thus have not been posting or reading.  A few things were pretty surprising to me whilst running about. Firstly, I did not enjoy my time away any less being on Solvaldi, Daclynza and ribavarine.  If anything, I have felt more energetic, alert and alive since starting these meds than I have in years.  And, secondly, I learned that you can travel through multiple airports with a carry on bag loaded down with pills and nobody at security asks you to open your bag.

At week 8 my blood results were undetectable.  In the Netherlands they will only check again at the end of the 6 months.  the monthly blood work they do is to check for anemia.   I think I mentioned before that in 2004 I was diagnosed with genotype 2 but in 2015 it was determined to be genotype 3, hence my treatment was extended from 16 to 24 weeks.  

I have to say the only mild side I am having is due to this new energy I often have trouble sleeping.  But you will never hear me complain.  Compared to the peg-interferon this is really a walk on the beach.  

Anyway, thanks for the support And to all others fighting the fight look towards the light at the end of the tunnel.



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