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Post Info TOPIC: One year post Viekira Pak-Not detected


Veteran Member

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RE: One year post Viekira Pak-Not detected
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Congrats Greg, that's amazing! I apologize for commenting so late. I haven't been on here in a while and just now catching up with stuff I've missed. I love hearing stories like yours! It's very encouraging and makes me feel a little more at ease about myself. Wishing you nothing but the best!!!



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34yo, Dx 07/15 HCV GT 1a, Vl:178660, F0/A3, ALT:213, Viekira Pak/Riba-12wk Tx started 2/6/16. *3/10/16-UNDETECTED@4wks! ALT/AST18,..4/7/16 -ALT/AST13 Still UND@8wks! 12/15/2017 Still UND!!!



Guru

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Thanks for checking in Greg!

Always great to hear success stories. smile

 

Best to you,

Dave



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63yy,HCV,2b,F3-A1, Sof/Riba,12wks Tx   SOT: 1/20/16, HCV-RNA 9,816,581, ALT 56, Hb 14.6

4wk: HCV-RNA <15 Detected, ALT 15, AST 17, Hb 13.6 EOT: 4/12/16, ALT 18 , Hb 12.9176a2f85d05d9c965eafe199f2ba9ba5.jpg SVR Achieved 7/8/16

 

Tig


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Thanks for the kind words, Greg! We all appreciate it. I'm glad we were able to provide some help and support when you needed it most. I remember you were really going through some hardships at home. Riba definitely is not your friend when you reach the end of your rope. Hopefully we were part of the knot you tied in the end of that rope that allowed you to hang on.

The fibrosis and viral load really don't impact each other in the way some think. Many people will have varying degrees of fibrosis, while having low or high viral loads. A high viral load indicates high viral replication, which can result in increased inflammation. Prolonged inflammation will lead to increased fibrosis. It's one way HCV damages the liver over time. They discovered that the viral load itself doesn't increase or decrease one's odds of SVR. Recently with the DAA's, like Harvoni, if your viral load is 6 million and below, and you are treatment naïve, you may qualify for an 8 week course of treatment. Anything else and they require 12 or 24 weeks. Each new protocol may change those guidelines. It's exciting to watch the improvements and advances coming at such a rapid pace!

Enjoy your new Hep C free future and don't go too far. We enjoy having you here and look forward to your advice and following your recovery and improving health. You may notice improvements that you hadn't even considered. That happens to people all the time. You've got a lot to look forward to, that's for sure! Good luck...



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Tig

64 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 7+ years!

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Thanks to all of you for your help and kind words. This forum was a great help to me during those "Riba" days. And then having to care for my mother in at home hospice while on treatment. That and the Riba about drove me bonkers so that's probably why I deleted my account. Had nothing to do with anything else. I looked forward to logging in here. A real good forum me thinks! Actually, I feel about the same as I did before for those who asked. But then, I had less than stage one fibrosis, .79 according to the biopsy so unlike many on here, I was never really sick to begin with. Its strange how some can have severe damage and a low viral load and others the opposite. But yeah, it is a great relief to have a deadly, contagious virus out of my system. So in that way I feel great!  Good luck to all of those in treatment or you "veterans" who hang out on here to help others. This is a very supportive forum so keep up the good work!



-- Edited by lonewolf on Saturday 2nd of July 2016 03:30:17 PM



-- Edited by lonewolf on Saturday 2nd of July 2016 03:54:42 PM

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Genotype 1a-Started Viekira Pak/Ribavirin on 3-5-15. SOT VL 21.8 million. Undetected at 4,8,10 and 12 weeks. 12 wks EOT-UNDETECTED

26 wks EOT-UNDETECTED

One year post treatment Not detected   CURED!!

Two years post treatment Not detected  Still cured!!



Moderator

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That is really great news!  Thanks for letting us know.  Feeling good?



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



Senior Member

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Greg,   Great news!  You did it.  It's sometimes hard to wrap our heads around this new life of SVR.... But it's real and we are lucky to have these new drugs available.   This is a special time.   Enjoy!!  Chris



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F 63,  1b  1974, no cirrhosis, fibro scan 5.8 F0-F1,fibro test .37 ,V/L 702987, ALT 90, AST 75.  ABBVIE Topaz II on 10-30-14 Viekira Pak no RIBA , EOT 1-22-15 SVR, ALT 37, AST 29, 4-15-15 SVR12 - fibro test .22,  1-21-16 SVR 52 ,  1-21-17 SVR 104! 1-21-18 SVR 3 years ,2020 5 years



Guru

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Hi wolf,

Thanks for updating us.

You got this "new math" down good.

(1a X 1) @ 21.8 mil X 4/12 = 0 + 8/12, 10/12, 12/12, 37/37, 53/53 = 0

WAS a 1a, now ... just a big fat zero!

Really big congrats on your calculations. biggrin C.

 

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



Guru

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Thanks for the update GREG, that Abbvie combo is good stuff. My wife did that and was SVR One year post. Viekria Pak is good stuff!!  Congratulations- It must feel good to have gotten that news. Your cured!!!!!!   RC



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 M-64) 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   



Senior Member

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Congrats man.

How do you feel compared to a year ago?  Do you notice any improvements?

Pablo



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44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



Guru

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Congrats Greg,

land thank you for posting in. It helps those coming along behind you to hear the success stories.

Syd

biggrin



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Contracted Hep C 1969. Genome Type 2, treatment naive. Began 12 week RIBA/sof/Dac on 12/11/15. Cirrhosis. VL before treatment 4m. Treatment extended another 12 weeks without Riba. No virus detected at 9 weeks.



Guru

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and Greg joins the ZERO club 

way to go! Another reason to celebrate Independence Day 



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Wendy 53 y/o, DX 1994, geno 1A F1

1999 TX 1 - Inter -non responder 2001 TX 2 - Peg + Riba - viral load tripled and taken off

T3:  Harvoni 12 weeks Sept. 19, 2015 ALT 41 AST 30 VL 541800 UND at EOT and SVR 24 ALT 18 AST 26 platelets 223

 

Tig


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Hey Greg,

Congratulations buddy! There was never any doubt, but it's always going to be nice to hear that word, made special by the battle we all fought for in the trenches, "UNDETECTED"!! Thanks for sharing your good news, it's a special day indeed!

WOOT!!  



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Tig

64 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 7+ years!

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Member

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Just got my one year viral load results in. Not detected just as it was at 4 weeks and every other time I was tested. Great stuff that Viekira Pak. And my viral load was 21.8 million at start of treatment. Sounds like a cure to me!



__________________

Genotype 1a-Started Viekira Pak/Ribavirin on 3-5-15. SOT VL 21.8 million. Undetected at 4,8,10 and 12 weeks. 12 wks EOT-UNDETECTED

26 wks EOT-UNDETECTED

One year post treatment Not detected   CURED!!

Two years post treatment Not detected  Still cured!!

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