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Post Info TOPIC: Liver pains post treatment


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RE: Liver pains post treatment
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Pablito wrote:

The pains have passed for the last few days. If they return I shall be relaxed about them.

A turkey for Christmas would be nice Jimmy.


 Yes it would Pablito, but this year I am doing a Rooster.



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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The pains have passed for the last few days.  If they return I shall be relaxed about them.

A turkey for Christmas would be nice Jimmy.  



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44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Canuck wrote:

Jimmy,

You offered? ...Pssssst, ya wanna buy a watch?"...

Nope, can't I'm afraid, went broke buying too many turkeys ... but hey ... maybe you wanna trade for a couple turkeys? They're nice ones! I'll let you think on it.winkC.


 LOL, for some reason that almost sounds like a ransom demand for a few friends I have. LOL

Sorry, just write it off as another Broism. no



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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Jimmy,

You offered? ... Pssssst, ya wanna buy a watch?" ...

Nope, can't I'm afraid, went broke buying too many turkeys ... but hey ... maybe you wanna trade for a couple turkeys? They're nice ones! I'll let you think on it. wink C.

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Midnight,

Nice to hear, " in the stillness", of all the absences. Nice to be UND AND have a lack of liver pains!

BTW, How did that bothersome "nose" thing turn out in the end??

I too am feeling thankful, being that it IS Thanksgiving over here in this nook of the world. smile C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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when I wake up and in the stillness can feel the lack of inflammation in my liver

- - - - - 

That sounds great.  Good to know you went through something similar Window but then came through it.

Yes, Adrian Mole is actually more for adults.  Very funny books.



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Cinnamon Girl wrote:
Pablito wrote:

17 & 3/4s....reminds me of Adrian Mole...did you have that kids book in north America?



Kids book?? Personally I prefer to think of the Adrian Mole series as being for kids of all ages... wink

Pablo, I agree with Cinnamon girl (now that I googled up Adrian Mole) ... sadly I had not been familiar with her writings, you Brits are a well-read lot, but sounds intriguing, especially the 13 3/4 one - hee hee, being that we were on the 3/4 subject!! But, I do know "mole" from Wind in the Willows! All good. smile C. 


 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Pablito wrote:

17 & 3/4s....reminds me of Adrian Mole...did you have that kids book in north America?



 Kids book??  Personally I prefer to think of the Adrian Mole series as being for kids of all ages...  wink



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi there, Midnight,

Thanks for dropping by, sounds like your liver has done some good healing in the months since your SVR in July!    Great progress already!!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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I had some considerable liver ache following SVR that lasted about 4 months.

More recently, this has passed and I now delight in those reassuring few moments when I wake up and in the stillness can feel the lack of inflammation in my liver...

__________________

Genotype 1A, Fibroscan 14, enlarged spleen.
Failed 48Wk triple therapy (Telap) treatment Jan-Dec 2014. 12 Week Harvoni/Riba started 22/12/15...

Week 2; ALT 50 HCV 96
Week 4; ALT 41 HCV 20
Week 8; ALT 34 HCV UND

EOT +4 weeks; ALT 27 UND

SVR 12; ALT 25 UND

SVR 18mths; ALT 26 UND



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Hey Pa. Glad you're still UND, but srry for the real pain of 300 pounds, ouch! I had normal ALTS until IVF and gallstones, I was diagnosed before then. I wonder if the pain reduces now you are not so worried?



-- Edited by Loopy Lisa on Thursday 6th of October 2016 06:02:18 PM

__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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17 & 3/4s....reminds me of Adrian Mole...did you have that kids book in north America?

You are right Canuck...an LFT test would have been a lot cheaper.

I'm not worried now as I am past the main landmark (SVR12) but I must profess the whole waiting thing was actually worse than the actual treatment....very pang, pain, ache and bout of fatigue being (mis)interpreted as a relapse.



-- Edited by Pablito on Thursday 6th of October 2016 05:58:20 PM

__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Folks as opposed to wasting money on "peace of mind".....

 

Pssssst, ya wanna buy a watch?

 

 LOL



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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Hi Canuck,

Yes that a little, but I don't think its that, I've had some serious ache for the last few days, really unrelenting, I'm not sure if its my intestines, or something above them. I don't think its my liver as my pee is a healthy colour, but something is going on. I don't have a blockage but I feel something a little hard and painful on my right side on the intestine. It kind of omits pain all up my right so I thought it was my liver, but it is actually lower. I must admit my mind is a little over drive about it, because I already had my appendix removed, so it won't be that. I will get it looked at and see what they say. Just when one thing gets sorted, something else bloody arrives lol! Hopefully its some kind of muscle injury. :)



-- Edited by Loopy Lisa on Thursday 6th of October 2016 05:51:13 PM

__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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Good for you Pablo, to go and get that extra PCR! Soooo ... shall we consider this your EOT+17 3/4 week VL then?, you will still get the EOT+24?? I consider it a big bonus, not a waste, worth every pence. Congrats on your EOT+17.75 week UND! I will still look forward to your EOT+24! Now everyone is gunna want a 17 3/4 one!

I think Loopy Lisa too is having a little of the pre-requisite squirmish/jittery waitin', waitin', waitin' syndrome... Loopy, you could always go get yourself a nice cheap quick LFT so you can see how your ALT is doing, that might feel good in the meantime to at least see those? Just fer sumptin to do, while yer waitin' ... ? Just a thought, in case you get to feeling real antsy. Why is it we all always have to do this fretting to some degree!! This whole waitin' thing sucks!

About our double-down-dog-cute lady, I liked her advice (just on principal) good for blood sugar spikes too. I have had very poor gorge-like-a-pig-'til-bustin'- twice-a-day habits all my life, and I tell ya, I shouldn't do it!! As much as I am lazy and loathe to make efforts to change dietary habits (I have made some!), I do think she had some valid points about overeating.

I have had some curious spots (for many years now) which I never really fully ever figured out, but since becoming UND, slowly they have lessened or ceased - so the jury is still out on whether they were or were not liver related. Torso pain, right lower quadrant, but more at side and posterior rather than abdominal, so had always just chalked it up to probably being back muscle/skeletal/orthopedic in origin or nature, but "maybe" it WAS liver all this time?

Another weird nearly-drove-me-crazy, intractably bothersome "spot", Both at the same time, a spot that felt deadened sensory-wise, frozen to the touch, neuropathy-like, but as well, was intensely deeply pruritic with no relief from scratching whatsoever!! This golf-ball sized spot too was right upper quadrant, but anterior thoracic, and above liver area -  hmm, obviously hard to describe eh? Hoping, they have gone now, or are going!

Boy DO I ever appreciate all the feedback and info we share, where would I be without all you!! smile C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Thanks Cinnamon Girl and Bubble - very reassuring to know that you both had liver pains post treatment and that they subsided over time.  The whole process is quite a thing to go through and I suspect it will be a year or so UND before I truly relax into this new-found life!



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Hello Bubble!!  Great to hear from you again, and belated congrats on your latest UND result in August!  biggrin

Thanks for stopping by, always good to hear from you!  How is the ankle swelling you mentioned, has it gone down now? 

 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Hi All !   Yes feeling great. Thought I would drop by. The pains do subside. Mine I thought were gone, but I get a day were my liver does locate itself. But I can say these days are far from what it used to be. Congrats Jimmy on your second time around victory. Great Forum Great people.



__________________

60 yrs. Geno1b 2001. 9mil. VL. �Failed Post Riba/Peg tx. 2006 46 weeks. Diagnosed 1A 2015(?) F3 fibr. 225k VL. Vikera/Riba 12 weeks 3/20/2015. "Undetected" start to finish. Undetected 1yr post tx.



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Pablito wrote:

LOL Jimmy.  I had never heard the phrase "double-down-dog" before she uttered it.  I'm gonna use it from now on in, which will no doubt confuse people here in the UK.



 Yeah, Pablo... I double dog dare you!!  Lol.. I`ve never heard the expression either, but after reading your posts here I just had to watch the video!  Well worth a watch for anyone who`s troubled by liver pains too. 

I really can understand why you felt the need to have a further PCR done, and of course you were still UND, but I should think it was well worth if for peace of mind.  (Congrats again!)  A couple of years ago I was going through a phase of feeling very tired, the sort of profound fatigue I used to get before I did my tx, and luckily I managed to persuade my GP to get a viral load test done for me, which of course was still negative.  I would have been prepared to pay for that peace of mind though, if I`d had to.  And by the way, I never get liver pains any more, 5 years post tx, although they did hang around for a while. 

Hi there, Skewed, good to hear from you again, sounds like excellent progress to me!  Good lifestyle habits really do make a huge difference... keep up the good work! 



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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LOL Jimmy.  I had never heard the phrase "double-down-dog" before she uttered it.  I'm gonna use it from now on in, which will no doubt confuse people here in the UK.

OK confession time: I was sufficiently worried about the liver pains and possible relapse that I went and got a private lab VL.  It was UND.  Unlike the US, in the UK you can't rock up to a lab for a blood test without a referral from a doctor so I've just wasted £300 on a private doctor and blood test that was always going to be negative.  At least I have peace of mind.

Skewed - good to hear your progress 2 years down the line.  Liver pains I can handle, as long as I know they will improve over time.

Pablo



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Pablito wrote:

The woman in that video is so double-down-dog sweet.


 OK I confess.

Ya made me look.



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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Perhaps we all have IBS! I was reading that can be a cause of upper quadrant pain, which isn't so daft really. Our poor bodies have been pumped with heavy drugs, so it has a right to complain. I also had no issues on a proper healthy diet, but when I eat bad, I start getting all kinds of tummy issues. I am actually thinking now its IBS caused by the acid I have. Thanks Skewed, that gives me peace of mind! :D



__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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In a couple of weeks I will be 2 years post treatment and I still have occasional liver pains. However, I am starting to feel good most of the time. That is the exact opposite of how I felt before treatment, but I'm alcohol and drug free and I exercise at least twice a week and I'm eating much healthier than I have ever eaten before and my heart flutters that were so severe during treatment have lessened quite a bit.



__________________

Diag. with hep c in 1992; A3:F2;  GT 1a; IL28B CT; VL 900k, ALT 150, AST 100 on 8/5/2014; SOT 9/5/2014  S/O ---VL 127 after 6 days; VL detected on day 18 but < 15.; --> UND @ EOT+ 1 year SVR!



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The woman in that video is so double-down-dog sweet.



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44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Hi folks,

Me too the last week, I'm getting nervous about it a bit. It is more of a dull ache but not in my shoulder. I am bloated too, so not sure if its IBS as I am also a bit acid it feels. Urine is normal and so is the other end. Its all a bit confusing! I was thinking to ask for an early test because I am now worried I failed the treatment. But as I am not the only one its a bit of an enigma really. I had this before treatment and it was gallstones but I cleared them. Wondering what it is now. I feel a bit offish! :/



-- Edited by Loopy Lisa on Wednesday 5th of October 2016 06:13:17 PM

__________________

Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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One always has to rule out only about a thousand (common or obscure) other reasons for abdominal discomfort as well! IS it really the liver we can blame for the right quadrant discomfort, or it is some other offending bit of something?? Who knows? Then, there is "referred" pain which can always present a confusing picture almost impossible to figure out first off. Don't ya just wish we had xray vison, or could just jump in there and look around? My mind always travels to common run-of-the-mill gall bladder grumbling, or sludgey, overworked ones, or ones with gravel or stones (but that's just me and my pet theories). Nice if a routine abd. ultrasound or tests have not picked up anything noticeably wrong with the GB then that might easily be struck of the list of about a zillion other things that might be responsible. Ya never know, lots of people even without a history of HCV can have gallbladder symptoms. Epigastric distress, bowel, skeletal, even renal can sometimes present weirdly. Lots of times, nothing is figured out, and pings/pangs of pain although disconcerting, may abate, disappear, or just is, and may come and go.

Worth keeping mental notes on it though, (especially if it concerns you) as maybe, later, in retrospect you may better glean a likely reason for it, whether you can prove it or not! In the meantime, I fancy your delightful scenario of scar tissue disentangling and letting loose from your liver!! That's a good image!

A long time ago, before treatment, I was studying up on liver (and pains), jeesh, there is just a TON of stuff out there about it, from sell-you-a-miracle cures, to horror stories, to funny and scientific ones!! I went back and looked and found this one again! I post it, not because it is right or the best, or anything like that, but only (1) because she has one simple cause and effect theory reason, IF you have cirrhosis and are OVER eating, and (2) because she is just (aaw) SO GALL DARN SWEET and only means well! Bless her heart!. smile C.

When Your Liver Hurts After Eating - YouTube

https://www.youtube.com/watch?v=lPipZlRVzGc
 


__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Good to know I am not alone and sorry to hear about your troubles SF.

Re my hypothesis that the pain relates to the liver healing, I have no proof and it could be wishful thinking, but it kind of makes sense to me.  If you cut your hand scar tissues forms to heal the wound, the tissue around this swells and it hurts as as a building site's worth of cellular activity takes place under the skin.  After years of abuse care of HCV my liver is now disentangling the scar tissue and some pain is involved.

Just a theory though.

Pablo



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Count me in on this as well. At least 4-6 weeks now under my rib cage. I will be having my ultrasound in a few weeks so that is a good thing.

I have some other things to deal with right now requiring more immediate attention so I will not overthink this.

I hope you will both feel well soon and that our pains are indeed part of the healing process as odd as that sounds.

 

SF

** I consider my self perfectly norBal ...



__________________

65 yo, GT1A, , Cirrhosis, F-Scan F4 33.5, TX Naive Harvoni 12 wks

SOT 2/9/16 / ALT 187 AST 114 VL 2.3M.    POSTS

EOT 5/2/16  ALT 35/ AST/25  platlets 126 C/B VL UND

EOT +12 7/26/16  ALT 25 /AST 22/ ALP 83  platlets 129 C/B VL UND

EOT + 24 10/18/16 ALT 27/ AST 20/ ALP 71 platlets 153 C UND

 * SVR *



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Thanks Jimmy.  I'm sure it's that (inflammation) and I will see the medical team soon.  I'm sort of tied in for the next 7 weeks into the trial I am on with its strict protocol as to what they can and cannot do. The trial people are the same as my clinical team. 

I'll mention the pains at my EOT+24 appointment when I'll no doubt get referred back to the regular NHS side of things, and take it from there.

I hear you about not knowing how to live post-treatment.  I became so focussed on treatment there is a little gap in my life now post-treatment....which will no doubt get filled quickly.



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.



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Greetings,

Most likely simple inflammation in the area surrounding the liver and not the liver itself. I am SVR 12, non cirrhotic and feel the same way.

We all need continued monitoring even after successful treatment and a proper assessment by your Medical Team is the only way to know for certain.

Always remember even folks who have never had Hep C need to be evaluated throughout life for things that are normal during the ageing process.

Brother, like me you are just now getting used to a life without Hep C. Our attention has been for a long time focused on Hep C. We do not yet know how to focus on normal because we have not had time to understand what normal is. ;)

 

JimmyK



__________________

Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



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Hi all

I've been getting quite a few liver pains recently.  More so than before or on treatment.  I don't think it's a sign of relapse as I was UND at EOT+12 so - thinking positively - perhaps it's my liver healing itself.

Before treatment I used to occasionally get brief darting pangs and dull aches in the upper right quadrant of the abdomen and, more rarely, a burning sensation in the same region with pain radiating to my right shoulder tip.

The recent pains are not like these.  They are more like a slight roiling sensation (to use Canuck's phrase) in liver area...like something is unravelling (?fibrosis untangling).

In my darker moments I wonder about HCC.  I haven't had an ultrasound for a few years, but it's unlikely given I am (only) F2.

The other thing to throw into the equation is that I haven't been drinking tonnes of water like I did on treatment.  I actually felt better on DAAs than off, and I now wonder was it the water.

Anyway, be good to hear your thoughts.

Pablo



__________________

44 y.o. male, HCV G4 since 1996, F-scan score 9, F2, Failed prior I/R, finished sof/vel/vox 8 weeks 5/16, pre-treatment VL 2 million, EOT UND, EOT+4 UND, EOT+12 UND.

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