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Post Info TOPIC: Cirrhosis


Guru

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RE: Cirrhosis
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Hi John,

The figures remain the same.

50% of cirrhotics show improvement of Fibroscan score by at least 1 stage, but it takes at least 3 years. 25% will show no change after SVR, and 25% will continue to show fibrosis progression.

My doc has just done his SVR followups, and there appears to be a gene at work. Naturally there is a frantic race to identify the gene.

Figures are not helped by the sometimes vague way cirrhosis is diagnosed, as well as the enormous range of cirrhotic changes.

Cheers

Malcolm



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm

Tig


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Malcolm had discussed this on several occasions. He was witnessing improvement, but it is slow going. Regardless of speed, any and all improvement is the objective. They are researching medications that reduce the scarring, but that has been slow going with mixed results.

Here is one of those discussions.  Cirrhosis regression



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Tig

63 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 6+ years!

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Guru

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Greetings,

 

The best treatment post SVR is good clean living. Mallani is a good person to follow in that regard. As he states, it just takes some time now.

 

Regards

 

JimmyK



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Harvoni TX 2 12 weeks. UND weeks 4, 12 and now EOT + 4 Weeks. SVR-12 09/29/16. All Glory, Honor and Thanks be to God.

"I go to war with the brothers I trust."



Senior Member

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Any treatment for cirrhosis on the horizon after successful treatment?  Is anyone getting reversable scarring results?



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 

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