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Hep C Discussion Forum -> On Treatment -> Be careful what you wish for...(Epclusa bonus sides)
Post Info TOPIC: Be careful what you wish for...(Epclusa bonus sides)
LamontCranston


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Be careful what you wish for...(Epclusa bonus sides)
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I really try to avoid laxatives, but when I get to the 3rd day, I gots to go, one way or another. I try to keep it to the lowest level of intervention, like prune juice first, then colace, then senna, or a combo of colace and senna. Next tier, butt rockets, that don't go through the stomach of course, then Milk of Magnesia (blugh!) but that is a no-no with Epclusa, or the evil lactulose.
At any rate, I vary the remedies, so I don't get in a rut with any one product.

But I also try to keep my diet sorted out with lots of fruit and veggies, water, unfortunately even a really controlled diet hasn't kept me on track. The pattern is improving, though, I can often go 2-3 weeks without a slow down, but the clamps go on without any apparent reason, and well...

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Lamont Cranston "Only the Shadow knows."

70 years old, retired IT Network support 33 years continuous sobriety in AA, ,DX'd in '99 with MS, DX'd with HCV 2, 2b , F0-F1 3/17/2017 VL 5.7m Started EPCLUSA 7/28/17

No Virus Detected on November 20, 2017 3 months after EOT
Canuck


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hm, oh dear. Well, I know many of us have travelled over this subject many times, what to try for constipation tendancies, and we HAVE often tried it all before, but, (for what it's worth) prolly not much in the offerring, but merely one of the only other things I can recall that I have left out of some of these conversations, shredded wheat! We covered brans (yuck)/fibres/cereals/fruit/veg of all various sorts - but oddly, just a big bowl of ordinary shredded wheat, every day, I found helps me with my "maintenance" (that and water are my two mainstays, water being #1), additionally, small doses of metamucil (over 2 or 3 days) when I have got myself into more of a bind! Once I have screwed up and got myself starting to be bunged up, it can take me a few days for things to resolve, so therefore, my preventative maintenance is very (more) important for me, and that IS where I can fall down. Maintenance is tiresome, but better than the consequences for me otherwise. My friend relies on see-sawing back and forth between constipation and then taking strong ("more effective" medicine she calls it) laxatives, but she does not realize (or maybe accept the premise) that the strong laxatives (she takes) actually trains and re-trains her bowels to NOT to work on their own, she is actually quite dependant on her laxatives now, and will not or cannot (it seems) get any normal peristalisis without relying on them! Laxatives, for me are and would be my last resort, at least the stronger ones. I can't recall for a long time now the last time I HAD to take anything stonger than metamucil. (In a way) I envy her, she just pops a pill, and eats whatever she wants, she never seems willing to think about what she is eating/drinking! If I ignore my daily water or fibre, I end up with work to do (or is that, to un-doo?). C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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LamontCranston


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On the other hand....all that good motility just stopped yesterday. So who knows? Even with gallons of water, veggies, fruit, fiber....of course things will swing back the other way soon enough.
Maybe it's all these nazis in the news making me constipated?

__________________

Lamont Cranston "Only the Shadow knows."

70 years old, retired IT Network support 33 years continuous sobriety in AA, ,DX'd in '99 with MS, DX'd with HCV 2, 2b , F0-F1 3/17/2017 VL 5.7m Started EPCLUSA 7/28/17

No Virus Detected on November 20, 2017 3 months after EOT
Jaggles


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Yep....Lamont ....during my treatment Epclusa every day it gave me a good bowel movement ....i was happy because prior to treatment the oramorph for pain was having opposite evfect it made me groggy..lol ..the water consumption helps ...a gallon a day kept other sides at bay...take care and best wishes biggrin 



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HBV 1982 Resolved  / HCV Undiagnosed until Sept 2016

female U.K. AGE 56

fibro score 6.9 

Viral load 3.5 million October 2016 

Geno 3

Treatment Epclusa

Undetected at 2, 4, 8 and 12 EOT , SVR 12 / 24

October 2016 Alt levels 190 now, July 2017 17

 
Observer


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Well, That's a crappy experience Lamont. cry So glad there was a washroom nearby for you.

Please take life easy while you're on treatment. As you said, you know it's working and it's going to be so worth it. smile

A



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61 y/o, Infected via transfusion Oct'83, GT-1a, F-4 cirrhotic,
tx Holkira pak/moderiba 12 weeks

4 years.... successful dragon slayer 
HepCGtype2


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Glad to hear the system is working and you were near a washroom lol

For what its worth I have had recent digestive problems and really severe constipation.
Nothing worked.
I tried a lot of different methods until last week for the first time, RestorLAX.

Worked like a champ.
Hopefully you wont be hit again and/or need it.

__________________

F. 58. Canada. GT2, likely since 1982.

Pre-treatment: VL ____, ALT 17 (to 40), AST 15, Fscore F0-1, Fibroscan 6.2kPa's, Abnormal Hb, RBC, HCT, Creatinine.

12 weeks Epclusa - SOT Aug 5/17, EOT Oct 21/17.

Week 4 - VL ____, ALT 10, AST 11.

 
LamontCranston


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So last week I was in here musing over how I was disappointed that I was still fairly constipated despite the "promise" of a liberating side effect. As my second week of Epclusa got underway, I was almost back to my old self. One glass of water, 2 cups of java and baboom. 

Well, today, I felt so happy that I had another "normal" day, so we headed off to my favorite Church of Consumerism, the CostCo warehouse, who has a nice clean restroom, which was very gratefully there for me by the time I developed really deep cramps in my lower abdomen....and eventually to a stall where I found myself soaked in sweat and nearly fainting after a vicious turn of diarrhea.

Ok, I take it back already. I spent the day hydrating again, and mostly slept the day away once we got home. Aside from that, just a mild headache and a lot of fatigue, and weirdly some insomnia most nights.

I know it all means it's working, though, so no biggie. I know it will all be for the good once it's over. But a reminder to be careful of what to wish for, whew.

Ok, just 1:36 to my next dose...

 



__________________

Lamont Cranston "Only the Shadow knows."

70 years old, retired IT Network support 33 years continuous sobriety in AA, ,DX'd in '99 with MS, DX'd with HCV 2, 2b , F0-F1 3/17/2017 VL 5.7m Started EPCLUSA 7/28/17

No Virus Detected on November 20, 2017 3 months after EOT
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