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Hep C Discussion Forum -> General Discussion -> Mavyret: Side effects and High BP?
Post Info TOPIC: Mavyret: Side effects and High BP?
Tig


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RE: Mavyret: Side effects and High BP?
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Hi Angel,

I’ve been on blood pressure medication for 30 years. It’s no big deal, especially if it’s just temporary. You may not need to do it anyway. Is your BP constantly high or intermittent? If you don’t normally have blood pressure problems, once you’re done with treatment you will be back to normal in no time. In the meantime, take it easy and try to rest a little. Treatment isn’t that long, give all the working out and the busy schedule a pass til you’re done. You need to finish and get this virus out of your body. 

Keep up keep that fight!  



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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RLS


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Angel, my first BP numbers were around 175/185 during early treatment and now around 135. Still high but down. I am on mild BP mediation. The meds have come a long was and very common for people to be taking it. Risk of no meds is much greater that not.

__________________

Male 54, DX 1992, GT 1B

2005 - Rib/Peg Relapse

2016 - 12 Week Harvoni Relapse

Mavyret (16 weeks), BOT 10/16/17, EOT 2/2/18. SVR 12 5/3/18, SVR 24 8/8/18
angelseven


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I am also having high blood pressure with mavyret... usually at home it is 130/85... now it is averaging 160/86,,, I am worried about the top number.  There was another girl that was on mavyret  another forum.  She had to go on High Blood pressure meds... I really don't want to have to do this.  I work out all the time and I think it is a direct result of taking this meds.... My doctor wanted me to monitor it at home... I hope the cardiologist I saw  a few years ago is on my insurance plan, he is very much into natural healing, etc.... I need to see what he has to say!

Best of luck,  angel/connie



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62 year old female      1a, f1-2, had virus 40 years   STARTED HARVONI for 8 weeks 11/19/14, relapsed one month after tx  ended in 1/15.  Fibrosis level was only .5 after fibroscan 12/15. Began treatment with Mavyret on January 20, 2018 for 16 weeks!  Ending May 12.
Canuck


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Hi RLS,

Glad you joined us here.

Congrats on allll-most being finished your 16 weeks of Mav! Only 2 more weeks to go! smile  VERY good to be UND at 8weeks! biggrin I am sure you will (ARE) doing it this time (for the LAST time)!

Sorry for your prior attempts, each having their own particular bitter disappointments and hardships. 

Many around here have done the long hard road as you have, only to end up in triumph with these great, new, ever more potent effective DAA's.

No, I have not heard much (at all) about a "direct" co-relation between DAA's being the only cause of high BP. Headaches are a common side of DAA drugs tho, and, as Tig mentioned we see headaches with a too low water intake while you are on DAA's. But headaches (all on their own) can also be a sign and symptom of high BP. Curious timing for you, so of course would raise this chicken or egg question. Did you ever have any high BP's in the past, or did the high BP only just develop during the 2 week period of headache? When did they start you on the BP med, what med is it, and is it working?

Tig is also quite right about the less recorded incidence of headache for MAV, versus Harvoni, and certainly waaaaaay less sides than what folk had to put up with when doing peg/riba!

Can't wait to hear your EOT UND! Just around the corner! biggrin C. 

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

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RLS


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Thanks Tig and good luck June on your treatments. The side effects of both Harvoni and Mavyret are nothing compared to interferon I took 12 years ago. So grateful for medical advances in recent years.

__________________

Male 54, DX 1992, GT 1B

2005 - Rib/Peg Relapse

2016 - 12 Week Harvoni Relapse

Mavyret (16 weeks), BOT 10/16/17, EOT 2/2/18. SVR 12 5/3/18, SVR 24 8/8/18
Tig


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Hello RLS,

Welcome to the forum! Glad you found us. You’re closing in on the finish line, good for you! Sorry to hear about the BP problems. I can relate, I’ve had it for decades. I’m also taking medication. If diet and exercise don’t work, then medication imo is worth it. We don’t need another silent killer lurking around. 

Mavyret has a very low side effects profile. Anyone can have an individual response to these drugs. Whether Mav caused your BP trouble, I don’t know. There isn’t any mention of it. It may be involved with the headaches, especially if you weren’t hydrated well. That’s one of the biggest causes of headaches with these new DAA’s. A gallon of water per day is recommended. Some use the “half your body weight in ounces“ rule. Either way, pour it on!

Stay in touch. EOT is near!



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Dandelion22


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Hi RLS, Congratulations on undetected at week 14. I'm in my 3rd week of Mavyret. I relapsed after 12wks Harvoni 3 years ago. I had BP problems on Harvoni, but so far not having them with the Mavyret.
Keep on slaying!
June

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F, 67, HCV since1980, GT 1b, Semiannual LFTs, Ultrasounds. First treatment Harvoni, SOT 1/2/2015, relapsed June 2015. Fibroscan F0-F1, LFTs only slightly elevated. Second treatment Mavyret 16 wks, SOT 1/2/2018, EOT 4/24/2018.
RLS


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Newbie here and catching up. In week 14 of 16 of Mavyret treatment. This is my third attempt at eradication. So far so good as my tests show the virus is undetected. Now it's a waiting game for SVR.

Had nasty headaches around week 8 that lasted 2 weeks. Luckily they went away. I also now have high blood pressure and on meds. Most likely unrelated to treatment but Curious if anyone else had an increase in their blood pressure from medication.



__________________

Male 54, DX 1992, GT 1B

2005 - Rib/Peg Relapse

2016 - 12 Week Harvoni Relapse

Mavyret (16 weeks), BOT 10/16/17, EOT 2/2/18. SVR 12 5/3/18, SVR 24 8/8/18
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