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Post Info TOPIC: Baseline Fibroscan 2 years later.


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RE: Baseline Fibroscan 2 years later.
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Well, Sieb - at least you now have a recent Fscore of F3 to (kinda) go by, derived from one additional means (fibroscan), to now add to the collection of other indicators of how your liver is doing. I mention the value of adding the ongoing fibroscan info/feedback to all other methods of assessements (exams, bloods and imaging) because together they are may be more wholistic, and singularily, they each have their own attributes as far as how much/what kind of data they can provide.

For instance, my very first pre-treatment U/S I had done, my liver showed "diffuse echo-texture with only a sparing around the GB" with the† radiologists notation that this may be indicative/suggestive of/consistent with "steatosis". Some imaging can also "roughly" guage the amount of fatty liver you have. Roughly this "diffuse echotexture" may start to show at a 30% level of fatty infiltration level. ie. so, the fattier your liver is (perhaps) the more echotexture they may see - anyway, that's my limited understanding of it from what I've read here and there - through the evolution of my infection being cured and liver getting better, in my post-treatment repeat follow-up U/S's there is no longer any radiologist notes making mention of seeing diffuse echotexture - I take that as limited and excellent feedback.

All info (combined), is good

Did you get any clarification on whether your doc had a concern about your CAP 353 level?, or, did he say what your 15% stood for?

I trust your doc will keep followig you well, and include repeat U/S's, repeat fibroscans, as well as your bloods. C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



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I received my results from my doctor yesterday. Sorry about the double reply.† <12.5 kPa is NOT suggestive of cirrhosis in this patient with Hepatitis C. However the kPa value of > 12.5 is suggestive of ADVANCED FIBROSIS in this patient with Hepatitis C. mine was 10.5. I was diagnosed F3 Hepatic Fibrosis and have follow-up Fibroscan next year.†



-- Edited by Sieb on Wednesday 23rd of May 2018 02:35:56 PM

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Ross

63 y/o, DX 1992, geno 1A

1992 TX 1 - Inter 3 mg 3x a week -non responder

1995 TX 2 - inter 5 mg 3x a week + 1200 mg Riba - non responder

2006 Last biopsy minor damage

Dec 2015 Fibrosure score F3 viral load 210000 ......Started Harvoni 12-14-15 (12 weeks)



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what i can glean from the various stages is that there are various stages within each stage... but if the numbers are going down rather than up that's a good thing...even staying the same is better than progressing to f4.



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Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.†Eot 6/25=Waiting for 3mo.VL.July=norm liverpanel.13weeks=UND



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Just got report from my doctor which in the short version says <12.5 kPa is NOT suggestive of cirrhosis in this patient with Hepatitis C.† I am 10.5 kPa which he called† F3 Hepatic Fibrosis and states to do follow up in one year. So I guess until next year. Thanks for your input.



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Ross

63 y/o, DX 1992, geno 1A

1992 TX 1 - Inter 3 mg 3x a week -non responder

1995 TX 2 - inter 5 mg 3x a week + 1200 mg Riba - non responder

2006 Last biopsy minor damage

Dec 2015 Fibrosure score F3 viral load 210000 ......Started Harvoni 12-14-15 (12 weeks)



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Sieb,

Don't you have an actual written report you can post an image of ?... that might help to decipher the results a bit more - without more data/details/clues then we are all kind of guessing.

Just keep in mind that the kPa measurements they get from fibroscans to "help estimate"†how firm your liver is (your liver stiffness measurement LSM), as well as the measurement derived from a fibroscan machine (that also happens to also have CAP/dBm†measuring ability) to "judge" possible fatty liver (steatosis) - that the key word here is "estimation". Fibroscan info alone does not paint the whole picture, when levels of fibrosis or steatosis are concerned, fibroscans ARE a valuable adjunct and an easy helpful tool to add to all the other labs, exams and imaging data they have compiled on you to keep assessing you. Fibroscans (and many tests) are helpful estimations, especially when repeated over time.

I would only be guessing (based on the lack of info), but I think the 10.5 might be? the kPa's, thereby only putting you in the lower end of the liver firmness range of F2-3? , as follows:† †https://hepatitiscnewdrugs.blogspot.ca/p/fibroscan-scoring-card-understanding.html

But you do need your doc to interpret all of your results for you.

How long ago were your U/S's? They are a valuable part of your estimations too, coupled with and along with your bloods and fibroscans, you just said your last U/S's were "normal", not when they were done, done last (how frequent they are).

The fibroscan machines (there are various models), some with and without the CAP ability to measure dBm (to do with possible "fatty livers"), the steatosis results might be expressed as simply "CAP". Generally the machines can measure approx. between 100 to 400 dBm's I think, perhaps your "15%" may have to do with that part of the CAP scan. Just guessing here, with nothing else to go on. C.

Oh, BTW† I have yet to confirm this ... but there was an indication at my hep docs office, my last recent visit there, that they are (now) wishing to consider that HCV patients have to be OVER 8 kPa to be in the F2 range (versus their old fibroscan range cut-off of 7.5), and OVER 10.5 to be in the F3 range (versus their old fibroscan cut-off range of 9.5) - but like I say, this was just info shared with me by a tech and has yet to be confirmed.††



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



Senior Member

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Sorry to read about your results.
I dont know what those numbers mean, since my results were F-Something.
Maybe it's better news than you think? I hope so!

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Lamont Cranston "Only the Shadow knows."

65 years old, retired IT Network support 29 continuous sobriety in AA, ,DX'd in '99 with MS, DX'd with HCV 2, 2b , F0-F1 3/17/2017 VL 5.7m Starting EPCLUSA 7/28/17

No Virus Detected on†November 20, 2017 3 months after EOT



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Well I had my fibroscan today and not sure it was a good idea. I was doing well and in good spirits until I got my test scores. My doctor has not called me yet but from what I have read my scores†are pretty high. This the info the nurse gave me. I know that Cap is way up there but not sure about the other two numbers. Any input would sure help.

Cap 353

Med 10.5

15%



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Ross

63 y/o, DX 1992, geno 1A

1992 TX 1 - Inter 3 mg 3x a week -non responder

1995 TX 2 - inter 5 mg 3x a week + 1200 mg Riba - non responder

2006 Last biopsy minor damage

Dec 2015 Fibrosure score F3 viral load 210000 ......Started Harvoni 12-14-15 (12 weeks)



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Ok, thanks for the input I was leaning in that direction. I'll let you know the outcome.†



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Ross

63 y/o, DX 1992, geno 1A

1992 TX 1 - Inter 3 mg 3x a week -non responder

1995 TX 2 - inter 5 mg 3x a week + 1200 mg Riba - non responder

2006 Last biopsy minor damage

Dec 2015 Fibrosure score F3 viral load 210000 ......Started Harvoni 12-14-15 (12 weeks)

Tig


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I agree, itís a good idea. You mentioned in your signature that you were previously diagnosed as an F3. Thatís advanced fibrosis, borderline cirrhosis. Since you have two years SVR under your belt, it will be an excellent measurement of potential (likely) fibrosis regression. I think two years is a good time frame that will provide you with a good idea of your current status.†

Contact your insurance provider for guidance on coverage. If your diagnostic testing is covered like many providers provide with their annual wellness exams, you may have little, if any out of pocket costs. Your doctor should be able to pre-qualify you as well. If the costs arenít in your favor, just tell them youíre willing to volunteer, if they buy lunch...†wink



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ† †Lab Ref. Ranges

Signature Line Set Up/Abbreviations† †Payment Assistance



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I would. I hate to see people having to pay for good following, but i would do it, as fibroscans are a very good adjunct (addition) to the all the other following you are receiving. Bloods and ultrasounds and imagings are all very good - the more info, the more good estimating, the better (I think). What have they determined your fscore is right now (by blood markers) versus without the fibroscan? You said, generally, all your bloods labs were "normal"? I am appreciating the continuing feedback I am getting by having my fibroscans repeated over time (amongst all the other following i get, including the bloods and U/S's). C.



-- Edited by Canuck on Saturday 12th of May 2018 12:40:01 AM

__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



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Hello all it's been awhile. I never had a fibroscan before I did the Harvoni and now it's been 2 years SVR and my doctor decides he wants to do one I think they just got the machine in their office and need to pay for it. I have had ultra sounds and they have come back with normal results. All else is normal as far as blood work. Just looking for opinions and I know were not doctors but I am wondering if it's worth it to get one? Doctor says they want to get a baseline. Any input it welcome.



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Ross

63 y/o, DX 1992, geno 1A

1992 TX 1 - Inter 3 mg 3x a week -non responder

1995 TX 2 - inter 5 mg 3x a week + 1200 mg Riba - non responder

2006 Last biopsy minor damage

Dec 2015 Fibrosure score F3 viral load 210000 ......Started Harvoni 12-14-15 (12 weeks)

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