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Post Info TOPIC: Almost 4 weeks on Mavyret


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Almost 4 weeks on Mavyret
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Thank you Cheddy ,When I first found out I really was scared and when I heard the price of the meds I really freaked out..Than when I heard from my doctor that my† insurance probably wouldn't cover it because I wasn't bad off enough yet I really freaked but I tell you it was within 2 weeks I got the letter they covered it .$28,000 worth of meds for $10.Wow I felt blessed than I heard of side effects,I got to tell you I hardly realized I was even taking them .The hardest thing was remembering to take at same time every day..At 5 week blood draw I was less than 5 copies.Go back on October.15 th to hear 8 week blood work.It was a breeze .I really didn't feel bad ever through .I had leg pain before I started this treatment but I have been a hairdresser /barber for 42 years so I am suppose to have legs that hurt lol.Mayvret really is a a huge break through.Much better price and side effects ,with me none,and cured in 5 weeks .Still had to take the whole 8 weeks but that was a breeze, And just to think I was so scared when I found out and it was a walk in the park.I kept waiting for the bad stuff from the meds to happen and they never did.The power of medicine is amazing.Thanks again !!!



-- Edited by Barbergirl58 on Saturday 22nd of September 2018 08:31:19 AM

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Rose



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Congratulations, Rose! More good news. You sure have had a good attitude. †I'm excited about your comeback. It feels great, doesn't i?.

I'm also excited that the new treatments seem to be more and more tolerable, and they're working so well. †It gives me more confidence for all the people who will be traveling this path. †Thanks for the uplift.



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin,†SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!! †I WON!!

EOT 6 Months 11/12/2016 †CURED



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Thanks Lamassa!



-- Edited by Barbergirl58 on Friday 21st of September 2018 08:24:44 PM

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Rose



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Congrats BG!



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Male, 66, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.



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518 Thank you so much!



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Rose



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woohoo rose!!!! yippee . ya. yahooooo! EOT. EOT. EOT.



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Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.Eot 6/25=L.July=norm liverpanel.*13weeks=UND * 6 months =UND: CLUB ZERO



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I made it!!!!!!7:00 p.m. I swallow the last 3pills of that amazing treatment!!biggrin!!! Feeling so accomplished!!!Thank you Tig for all the support !!How are you feeling?



-- Edited by Barbergirl58 on Thursday 20th of September 2018 02:11:15 PM

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Rose

Tig


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Hey Rose,

Today is THE DAY!

23983622-C9E0-4E5F-9D1D-2442676C95B4.png



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

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Canuck ,it was so easy .When I first found out I was like thinking the whole world was ending.But hey it was a setback for a comeback and I am back Woo Woo.Thank you



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Rose



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Thank you Tig !I am having colonoscopy on the 1st(trying to check myself out totally lol) and doing blood work for recheck a week later than see good ole Doc on 15 th to hear the great news again!I am so happy !!!!!Thank you so much



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Hey BG,

Tig points out here, and you and 5 were "yaying" over in the sidebar about it today - EOT tomorrow! -congrats!!†biggrin†C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)

Tig


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Hey Rose,

A little birdie told me tomorrow is your last day of treatment! Congratulations!!†

Are you going in for end of treatment blood work or are they going to make you wait 3 months? I would insist, it just makes for a great morale boost to know you finished with a big shiny ZERO on the report!†

Well done, Warrior!†smile



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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Tig & Hoodietree thank y'all for the motivation and the positive vibes.Definetly hoping for positive news on Monday.I love this forum .I will keep y'all posted!



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Rose



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I feel very inspired by your story Rose thank you!†

2 gallons a day! Ill shoot for that today and see if it helps.†

I dont think Im ready to add in any vigorous exercise yet but for sure after Im done with the meds in 6 weeks.†

Thanks again for your inspiration



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†

Tig


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Hi Rose,

You sound very positive and upbeat, I like it! Itís great to hear about the improvements youíve noticed along your journey and Iím certain they will continue. Your routine sounds far healthier than my own, I think I should follow your lead and get more active. Iíve found myself sinking further and further into my recliner this summer! My bad... †Binge watching TV has become my go to activity. I blame it on the summer heat†no† You give me inspiration, so Iíll try harder.†

Keep up the good work and following the excellent hydration schedule youíve accomplished. Two gallons per day must keep things flowing nicely. Good for you!†



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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Thank you Tig,Yes it was 5 weeks 1 day when blood work was done .I pray that it is cleared out .Definitely going to keep taking these meds till the last pill is taken.I lost the weight 28 lbs during treatment and yes I definitely have been eating right .left sodas alone almost 2 gallons of water a day and added the gold gym stretch band exercise to my day .HelpC was certainly a game changer in my life but they always say out of something bad comes something good Also my husbband just built bar in back yard a year ago ..I wasn't a big drinker but a few months before finding out I started having 2 drinks about 3 days a week ..I contribute that to waking up the Hep C..I could be wrong because I never thought I was feeling bad ..But now I do have lots of energy and sometimes I have a zoomie tired effect..The leg pains still there but I have been exercising thru this past week ..I am praying for good results.I pray for all dealing with all illness to get full recovery.Thank you Tig so much for helping me to understand this process .I will keep you all posted



-- Edited by Barbergirl58 on Thursday 6th of September 2018 09:42:01 AM



-- Edited by Barbergirl58 on Thursday 6th of September 2018 09:43:57 AM

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Rose



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Hey BG,

I saw your hello from earlier today over in the sidebar - congrats on speedily getting near the end of your treatment! It won't be long now and you'll be getting some good and relieving news. So, you had your end of treatment (EOT) bloods drawn a little early, they do do that sometimes, especially on these shorter courses they put people on (like you on your 8 weeks of Mav), they sometimes check a little earlier than the actual EOT date.†

But even if you have NO detected virus showing from your early EOT testing, of course they are going to tell you to keep taking every single pill until you have finished them all. And even after you are finished your pills keep drinking lots of water, water is just plain good for us, but with the treatment that you are soon to complete, it is still a good idea to keep drinking well. Good for you and your kidneys to keep flushing your body out.

So, have you still been finding you have this abundance of energy? Did you experience insomnia or anything like that? Or, was it that you just found you had extra energy?

You mentioned leg pain? and you were wondered if this was just you and work related or if it was the hepc, that will be interesting in future to see if this improves for you - I hope so. Perhaps you will notice improvements in areas that you were not even aware of that were lacking in some ways - that's always good too!.

I am glad you did not seem to have too much trouble while being on the treatment, save perhaps for this "energy' thing, maybe that extra energy was a good thing, not a negative†smile ... I wasn't sure how you read that symptom. I think your sudden and unexpected diagnosis must have been quite a shock to you, as you mentioned dropping some weight before you got started on your treatment. Perhaps the weight loss even if it might have been in a stress reaction perhaps was overall a good thing? - maybe a few pounds were needed to be lost?, I hope you are not missing the pounds you lost.†

Once you are finished up and rid of this virus, you are free to work on areas of your health, unfettered by this culprit that was in all likelihood going to rob you more and more of your health.†

So glad your virus was discovered so you could get rid of it. Keep us posted. C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



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Good morning Dishbrat , thanks for letting me be a part of everyone supporting each other through this .So happy you are done with treatment and so happy at 4 weeks undected.I† been having leg pain a little numbness in one .I started with this before I was diagnosed I don't think it's† from the meds.Maybe from the virus maybe from standing all them years of hairdressing 40 years.I am not sure.Did you have any sure effects while on Mayvret?I make sure to drink a gallon or more of water .I definitely need more exercise though.What effect from meds did you experience?



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Rose



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Hi Rose! Glad to have you along this journey, with the rest of us!

I just finished Mavyret about 4 weeks ago, have 8 weeks to go until my 12 wk draw, but have been undetected since end of week 4. Glad you are doing so well on the treatment, if you'd have any questions, the folks here can most likely help you, if nothing else, you'll always get support, and a smile here :).

Good luck on the last half of your treatment, keep us posted how things are moving along!†



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45, F, Dx2000, VL 5.3M, ALT 113, AST 45, F0 (Blood work), GT 2 (? Couldn't establish subtype??), treatment naive, type 2 diabetic, recovering addict 11/22/02

RX Mavyret, 8 wks. SOT: 6/5/18. Liver function blood work at the end of week 3, for my Family Dr.† ALT 50, AST 24.

5wk-UND, EOT 7/30/18



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Thank lots! I am so glad to be getting thru this fairly easy..



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Rose



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yay barbergirl. onto the 5th week



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Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.Eot 6/25=L.July=norm liverpanel.*13weeks=UND * 6 months =UND: CLUB ZERO



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Thank you I will try to figure it out lol!!5 th week starts today!Yay me!



-- Edited by Barbergirl58 on Friday 24th of August 2018 05:30:10 PM

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Nice BG!

We'll all wait with you, looking forward to seeing those good lab results from your Sept 1 draw.

While we are waiting, have a look at Tig's helpful link for setting up signature lines ...†Signature Line Set Up/Abbreviations††smile†C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



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Thank you Canuck.The Lab posted were the only ones I had done .They were before treatment started I am starting 5weeks tomorrow I am so anxious to know where I am with this now.I will for sure keep this forum updated .



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Hi B.G.,

Welcome here from me too. Glad you found us and this place, and glad you feel you have been learning a lot here. Me too, i have always been glad i found this place, nice folk here and lots of info, it helps. We all learn a lot from each other.

Good you posted your labs and shared your info, it would help if you put some of your (pre-treatment) stats, labs and info into a signature line like the rest of us do, assists greatly in ongoing communications.

Something like this? ... Recently diagnosed GT 2, VL 18,000? ALT 27, AT 24, Low Fscore. Tx Mavyret 8 weeks - SOT Aug ___ to EOT Sept ___, 2018.††

Then,† when you get your new lab results from Sept 1, add them to your sig. line for progress comparisons.

Tig mentioned hep A and B immunity, were those assessed for you before you started your hepc treatment?, and did you happen to get a "fibroSCAN" as well, and did they do an abdominal ultrasound on you?

From the sounds of your posts and your first post, it sound likes you are feeling no ill effect feelings from taking the anti-virals - that is great! It is true that some people do and some people do not feel the drugs/treatment. And same for having the hepc virus itself, in some people the disease seems silent.

Wonderful your virus was discovered so it could be treated and cause you no further harm.†biggrin†C.†



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)



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Thank you so much much for this information.I can't wait to hear undetected!!!!



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Rose



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Thank you much.Its nice to be able to talk to people about this silent virus that rears its dirty head when you not expecting it lol but I am happy to be on this wellness train!



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Rose

Tig


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Hi Rose,

Your Fibrosure score of .31 is considered low in the big scheme of things (F1). Iíll include a link to the scoring table used to determine that number. Understand that any score that isnít considered normal, automatically is considered high. That doesnít mean itís dangerous or seriously high. I had 3 biopsies and was considered F3, which is severe fibrosis. You are still relatively low on that scale and should respond well in time and that stage should improve. Some notice fairly quick response to treatment and those scores drop faster than someone like me that has significant scarring. Often, the inflammation causes these numbers to skyrocket and once the virus is destroyed, the F score drops. In genotype 3 patients that is particularly apparent. Everyone is different, yet similar! †Some of us with severe fibrosis and cirrhosis take years, if ever to respond. Once the liver scars in such a fashion, the damage is real and long term in many cases. Your results all look good and the low fibrosis score really is in your favor.

Fibrosure Stage



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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welcome to the wellness train rose , these new daa drugs are heaven sent:



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Gt:1a-36yrs†.Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on†3.6.18:.†A1 activity.† f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND.Eot 6/25=L.July=norm liverpanel.*13weeks=UND * 6 months =UND: CLUB ZERO



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So sorry to hear you had to go through 7 months of treatment.These 8 weeks is making me loose my mind and thank God no side effects really couldn't imagine that 7 month journey but thank God you got through it and happy you here to help everyone here understand .Heck you better than the doctor with helping me understand! Thanks again



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Rose



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One of lab says Fibrosis score 0.31 and it says high .What do you think of that fibrosis score Tig?I appreciate your time.I am learning so much here.thanks



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Rose

Tig


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Hi Rose,

I removed the large screen shots and left the attachments for review. Sometimes the screen shots are such large files, they overtake the viewing area. Such is the case, so we can simply open your attachments to see the results.†

Overall, your results are quite normal, which is fantastic and indicates additional positive aspects regarding the outcome of treatment. It appears to me that you caught this early and any damage is minimal. The F1 fibrosis stage is quite low and as you mentioned, does indicate the complete lack of cirrhosis. F4 is considered cirrhotic. Even then, a compensated cirrhotic >F4, can live without too much intervention. There are additional considerations that cirrhosis presents, but youíre nowhere near that.



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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I just posted the blood work done before I started treatment .Thanks for having me here.I absolutely love having this forum to help me thru this .Thanks Iris



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Rose



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Not sure if I did that right but I screenshot† what my blood work showed lol probably to much stuff but it's all the blood work that was done before starting mayvret.What ddo you understand from this . please help me understand it Thanks



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Edited for attachment size. They can be opened from the icon.



-- Edited by Tig on Wednesday 22nd of August 2018 02:59:13 PM

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Rose



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Hi there! Welcome to the board of healing!
You should be able to get copies of your bloodworks, call and ask for them.
Will be following your progress :)
Blessings, Iris

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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naÔve....UNTIL 7-01-18† !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)

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The bloodwork we are usually curious about are, the viral load, the liver enzymes (ALT and AST) and genotype. There are plenty of others, but those are always the important ones when starting and finishing. Tests can be done anytime, but typically before, at 4 weeks, the end of treatment and always at 12 weeks after ending treatment, or a combination of.

You mentioned a figure of 18,000. If that is actually your viral load, itís very low and the reason you were prescribed 8 weeks of treatment. To provide some comparison, my viral load prior to starting treatment, was 5 Million. I took the old standard of care, 5 years ago, which included Interferon, Ribavirin and Victrelis, for 7 months. It was awful and Iím so glad you avoided such treatment drugs. One other bit of positive news is, genotype 2 is very receptive to treatment and I expect you to breeze through it, with glowing success!

Ask your doctor if they have checked your Hepatitis A and B immunity. Itís a good idea to have that checked and receive your immunizations against them. The last thing we need is to be exposed to and contract either form, after carrying Hep C around. They may have already done that, but itís a good idea to get those vaccinations done.†



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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I am really sorry confused about it all the blood work stuff don't know exactly where my levels are yet but I got on treatment 4 weeks tomorrow.First treatment ever and treatment is mayvret .It's 8 weeks toal so 4 to go .I go get blood work done on September 1st to see viral load is at .I know it's Hepatitis C genotype 2.I remember her saying I had like 18000 spikes of it ,lol I could be wrong but I said dang I must be about to die and she said No that is really not like it sound it could be a lot higher . No cirrhosis.But I am so confused I am just taking the meds and from reading alot I have alot of questions when I go back for her to give me results of blood work.Thank you so much for letting me know about how to search it here.I absolutely am so thankful to have this forum to talk to people about this .I will keep posting.



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Tig


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Hi Rose,

If youíre looking for extra information and discussion on Mavyret, use the search function at the top of the page and enter a keyword or two. We have a good bit of info here that you may find helpful. Iíll be glad to help if you need help tracking down anything.

When you have a moment, can you set up your signature line? You can include any number of things, genotype, pre treatment blood work, etc. Thereís a link to directions in mine, if you need it. It helps to know a little history when replying to your posts, without needing to look back. It helps my aging (non existent) memory, too! You can see what some of us have done.

Nice to have 2 sons that are ER Nurses! †



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Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



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See the light is the perfect name ,I am going to need you to stick around because that's what I am so anxiously waiting for lol Great name.Yes I am doing great .From going from everything is ok to being told I was hep c positive was a life changer .But I pulled my big girl pants up and said not today devil and here I am 4 weeks into treatment and 4 to go and I know we will all get thru this!!Thanks for having me here.



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Welcome Rose,

Lovely to have you join us. Sounds like your doing great. I finished Epclusa a month ago and have to wait 2 more months to know if it has worked. So many success stories here, we can all feel very positive we will succeed.†biggrin



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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Thank you . The gastroenterologist said I don't have any cirrhosis.Genotype 2 .Going to get rest of blood work and post.I went in to doctor because my sister always goes check on herself and I just never go .I have been married 30 years have 3 sons.Busy raising them I just neglected myself never ever feeling bad .2 of 3 of my boys are emergency room RN's so if I ever did have health questions I would just ask them but I was blindsided when I went into the doctor and said I haven't been to the doctor in a long time so just test me for everything .That was 3 months ago . Everything came back good except liver enzymes .That when I was sent to digestive doctor and luckily I got mavyret .Feel so blessed to have have it .4 weeks in and another 4 weeks to go .I will keep posting.Thank you



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Rose



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Thank you so glad to be here with people going thru the same thing with us all having the goal of getting cured of this horrible virus.I am 4 weeks into the treatment and really cannot wait to see the next 4weeks go by and I pray that it is cleared out .I feel so truly blessed to .have gotten Mayvret.I know it is such a new drug and I have search all over to hear from people who was treated and their outcome.Cant find many reviews from people who got these meds so i will for sure keep posting here .to let everyone know how well it work for me.Thanks again



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Rose



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Welcome BG, glad youre here. Interested in learning more about you and really happy to hear of your success!



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God.†

Tig


Admin

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Welcome, BG! Glad you found us and hope you believe in the power of these awesome new drugs. They are the real deal and you WILL be successful. Enjoy that energy, and send me any you canít use, lol!†

If you know some additional information about your genotype, history and blood work, please add it to your signature line (via the profile page or the link in mine) and tell us a little about yourself. If you have any questions, donít hesitate to ask. Iím glad youíre here!†



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

Hep C FAQ† †Lab Ref. RangesHCV Resistance

Signature Line Set Up/Abbreviations† †Payment Assistance



Member

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Posts: 29
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Side effects have only been more energy.No headaches no naseau.I pray to God this virus will be cured after this treatment.I will keep y'all posted on this new treatment.



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Rose

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