Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Post Info TOPIC: Variable Fibroscan results?


Guru

Status: Online
Posts: 2958
Date:
RE: Variable Fibroscan results?
Permalink  
 


Hi again Midnight,

I remember you! (now), it took a minute.

We spoke before (on fibroscans, and other things).

How are you doing/feeling now BTW?

My opinion, for whatever that's worth, on the fibroscan score(s) ... is that your fibroscans are probably near enough to be correct in their "downward" indications - fibroscans, as Tig puts it, can be considered "ballpark", as fibroscans are just "tools". Another way to measure something that is just downright pretty difficult to measure perfectly.

I would be (and would have been) happier, if you had had a lot more fibroscans (and labs) done all along, period, like more than one pre-treatment fibroscan, and then a fibroscan every 6 months post, and as Tig mentioned, abdominal U/S's and other imaging done maybe up to as often as every 6 months as well, which can be justified just because of your hx of a previous F4 at 14.2 kPa's, and, it would just be good following.

The more tests (like fibroscans) are repeated and keep showing up similar things, then the better I think they may show a truer direction.

I bet you were 14.2 kPa's (prior) or close to it or at least "up there", and after cure i bet you did decrease this amount of liver firmness (down to the 9 to 11 range). I am thinking various parts of our livers may NOT be identical and uniformly hard over every square inch on any given day, thus why they take aprox 10 different readings (or more) during a fibroscan until they and the machine are satisfied that each of the ten reading are accurate "enough" to be used in calculating an "averaged" reading - they pick up different readings and they average these results into one reading/one number. I have been told (on some of my fibroscans) what some of my differing "multiple" readings were within that session - they were in a "range" from around 14 down to 7.8 (all at the same session) - the average result gave me my first post-treatment kPa drop of 11.2 as my first drop, from the prior pre-treatment kPa of 12.6.

I can only conclude (by your limited repeated fibroscans) that you have(generally) decreased your kPa's, substantially, and perhaps some parts of your liver do measure up to around 11, and maybe some parts of it are around 9, and maybe some of it is likely even less than 9 or 11! Law of averages!

If it does not cost you, have more testing (of everything) including U/S's and imagings, ask for AFP's to be done with your labs, try to get more regular and frequent fibroscans done.

I have had quite a few fibroscans (post) done as I'm in a further study, I got one done not long ago that was so low i did not believe it, then the next one done after that was higher, which I did believe much more - neither numbers really mattered because they were both so INCREDIBLY low they had to be a correct and outstanding indication of my decreased stiffness - I am in the boringly normal liver stiffness category fer sure.

I hope your kPa's just keep decreasing for you too. : ) C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

(SEE UPDATES IN BIO)

Tig


Admin

Status: Offline
Posts: 8597
Date:
Permalink  
 

Hi MN,

Fibroscan has been known in some circles as a ballpark figure. There are several variables that can change the results, not just the actual fibrosis. The newest probes and machines are providing more improved results however.

Fibroscan is actually an average of several pulses of energy. The differences lie in equipment used, technologist, BMI, fatty liver, angle and technique. It does look like your scores are relatively close though. The score you listed of 14, along with the evidence of splenomegaly (enlarged spleen) tends to support the higher score, indicating the likelihood of cirrhosis/portal HTN. Im not a doctor, so yours will have to discuss that with you and come to an accurate diagnosis. I would want a current Fibroscan, perhaps an MRI to get a better picture. I would recommend a full abdominal ultrasound as well. That can be very helpful in determining the health of all your innards. With advanced fibrosis, thats recommended on a 6-12 month schedule anyway.



__________________

Tig

62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

Hep C FAQ Lab Ref. Ranges

Signature Line Set Up/Abbreviations Payment Assistance



Member

Status: Offline
Posts: 22
Date:
Permalink  
 

Hi all,

I wonder if anyone can comment on this.

I received a fibroscan score of 14.2 back in 2015 prior to SVR.

I then had a further scan with a score of 9.2 in 2017 post SVR

Today I had another scan with a score of 11.2.

What gives is this normal?

I haven't had any further bloods since 18mth SVR

Tony



__________________

Genotype 1A, Fibroscan 14, enlarged spleen.
Failed 48Wk triple therapy (Telap) treatment Jan-Dec 2014. 12 Week Harvoni/Riba started 22/12/15...

Week 2; ALT 50 HCV 96
Week 4; ALT 41 HCV 20
Week 8; ALT 34 HCV UND

EOT +4 weeks; ALT 27 UND

SVR 12; ALT 25 UND

SVR 18mths; ALT 26 UND

Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.

Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.