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Post Info TOPIC: Hep b reactivation


Guru

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RE: Hep b reactivation
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Hi, 

Without reading all of your old assessment data, we would just need to determine if you HAD "chronic" hep B or not, and/or whether you had just had a bout of hep B in the past, got over it all by yourself and never became a "chronic" hep b carrier.

If you were a carrier of "chronic" hep B, then you might have been at slightly more risk (than someone who did not have chronic hep B) of "re-activating" during hep C treatment. - but Tig is exactly right - this is SO rare.

You might review and share with us more of your hx about having hep b, more fully, had a bout of it when?, ever immunized for b?, ever tested for chronic hep B in the past - then there would be more info to go on. 

Being followed with LFT's will always be good medicine after you have been cured of Hep C, and, if you have ever had hep B.

If you are still questioning whether somehow this rare thing of B reactivation might have happened to you, then you have to have the doc tell you what your hep b status was and is, mostly assessment (of where one is at with their hep b status - whether you carry chronic hep b or not) is done before hep c treatment is started, likely you were assessed pre-treatment too, they usually do, but you can go ask and find out.

Likely there would have been signs and clues, had one re-activated their chronic hep B.

 

Too long, a gangley link about hepb/c:  About contracting HBV and HCV at the same time 

 

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)

Tig


Admin

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Hep B deactivation is an uncommon reaction to treatment with the new DAA’s. It does occur but rarely. I don’t have the rates of reactivation on the top of my head, but it’s low.

If someone were at risk and actually experience a reactivation of their HBV, the symptoms are going to be the same, including the elevations in the enzymes and LFT’s. Generally if a patient is at risk, the doctor should be aware of it and perform the necessary annual testing to assure the patient remains clear. 

Here‘s a thread where we have discussed it:  LINK. Canuck is our resident HBV Professor, she’ll chime in when she sees the post. 

 



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Tig

63 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 5+ years!

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Moderator

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I have not had any reactivation since treatment.  I did have to repeat my hepA/B injections series. Apparently my blood work looked like I had never been vaccinated before, though I had. I'm not sure what you mean about reading the warning differently.  What did you read, what did your doc read.

Tig? Canuck?  You two know a lot more about these things.  What do think?

 



__________________

GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



Member

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Has anyone had hep b reactivation after hep c treatment. I was treated in 2015 and at that time reactivation wasnt a warning. Its been 4 years. My doctor says when I was treated my hep b was negative but I read the warning differently. Could I have reactivated and not know!

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