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Post Info TOPIC: Hoodies Epclusa journey starts 7/26/18


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RE: Hoodies Epclusa journey starts 7/26/18
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about the 'mom' , i just glazed over and wondered what it really meant. hahahaha

 

harry, yes one of spring tx ppl had that

i have gained 4 pounds since eot cryhmmevileyeblehdohconfuse; i hope it is just from less energy and movement... eating is the same. will have thyroids in the spring, had my 6 months quant,af & liver panel lab today. i hope the turn around was as fast as the 12week



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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Hi Hoodie really hope your results are ok ,how are you feeling now ? Istill have a mth to wait before i get final results fingers crossed ..have you heard of people poste tx getting numb tingly feet toes at times ? Im wondering if its from tx or hot weather fluid retention or maybe that i had the virus for so long ,i wud be interested to know if anybody else has heard of this,probley just me maybe.anyway good luck with everything .so hot over here atm and wow these last few weeks waiting for results are going so slow..take care..

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I was going to say...Mom? I missed that part, lol. Did I miss it? Hoodie do you have kids?

So good to hear from you, say safe in all your extra commuting, keeping fingers crossed for SVR for all of us.

Bb, Iris



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60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



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That's funny.  Still reads: IM not Mom -ha.  

We get your drift though and I'm really eager to hear from you all just as soon as you can.

It's going to be a good news week.

yawn WOW!

 



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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Thanks Cheddy and 5!

Please excuse typo in previou post. Should be IM still not Mom still. Argh. 

5 Best wishes on your labs today!

looking fwd to celebrating with you, Iris, and STL very soon



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Welcome back Hoodie! You will feel top of the world when that 12 week viral load comes back undetected.



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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.



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hoodie, so glad to hear from you

i still have some bad days, but hubs is having more good days so he is hope walking

i'll go mon. for labs, soon you me and iris will have our labs... i wonder whats up with STL

i'm glad to hear your drive isn't awful and that you are getting good sleep



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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Hiya Hoodster,

Good to hear from you.  I'm glad you're starting better.  All meds and all people are different but it usually takes a few months for system to readjust. That should fit well with spring on the way.

I'm so excited to hear about your bloodwork!  The closure is thrilling.

Sleep tight,

Cheddy



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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Hi Friends!!

Sorry Ive been so busy lately and not checking in regularly.

Canuck, no I didnt have to relocate for this job but my commute is about 30 minutes more total, not too bad but enough to feel the difference.

Mom still sleeping 10 hours a night when I can get it. Often around 8-9 hours will do. 

I think Im starting to feel better finally, but its up and down. I think my stress tolerance is improving. 

I got my 12 week post treatment blood draw done yesterday, so Ill report back with my UND as soon as possible! 

Thanks and love

hoodie



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Yeah, Hoodie.  Get your butt back here.  We didn't quit caring about you, you know.

 



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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i was thinking about hoodie too... jobs have a way of really taking it out of a person. Especially the full time jobs that are intense.

i hope all is well her way



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO

Tig


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So, what the heck happened to our buddy, Hoodie? I’m feeling a little sad about her disappearance! Now, I’ll feel much better if you check in, Hoodster! You should be the CEO by now, tell them you need to check in with the Board, the Hep C Board of Directors! We miss you... wink  



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62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Hi Hoodie, hope you are well for the New Year! Canuck was right the first two months I was on Epclusa I was never so tired in my life.

I was one of the patients who had to feel much worse before I could feel better ... it even concerned my doc as he said my reaction to Epclusa was definitely an edge case but he said just tough it out as my viral load crashed dramatically and labs were normal. Now I have plenty of energy, and feel better than I have in ten years, well except for the arthritis and the bum knee but one grows old.



-- Edited by lamassu on Saturday 29th of December 2018 07:12:40 PM

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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.

Tig


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Hoodster,

I missed your P update, lol! That could’ve been a soggy situation. I would’ve been looking for a bush or an alley, just in case. I hope everything is going well smile



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62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Hoodie,

How's the new job going?? Did you have to do a major "re-location" (to another city) for this job? Just wondering. That was my impression but i could be wrong, it seemed like you did not have a lot of time for a big pick up and move. confuse

My other curiosity is how much fatigue you still have. I know you were like me (and lammasu) in experiencing some profound fatigue, and big needs for many hours of sleep per day. But I have been gleaning this fatigue has lessened for you now after EOT? and that you are requiring less hours of sleep? - maybe you already said this elsewhere on another thread but i cannot recall exactly what you have said on this subject. I recall the intensity of lamassu's fatigue was more related to being severe "while ON-treatment", whereas mine was profound for quite a while before treatment and of course continued just as profound or thicker while on-treatment, and then was slow to improve for me post-treatment - I am just wondering how the fatigue and sleeping has morphed/evolved for you. C.



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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OMG Iris, I went to yoga yesterday and the instructor was late so we couldnt get into the building, I had to pee so bad! It was such a terrible emergency! Then the instructor arrived and announced that she didnt have the key to the church where we do yoga So I had to drive about 5 miles to the nearest bathroom. It was quite an adventure! I was so nervous I might pee my pants! That put the P in PTSD, lemme tell ya! 



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Hoodie, I slacked off the water too. I was way down the last month of treatment, and now I'm back to my normal, several cups of coffee, and maybe two glasses in the day, a beverage with dinner, and that's about it. I try no to drink before bed but that's when I like some herbal tea. And a short glass of water to take vitamins with. I do sometimes go on a juice binge, but that's a lot of sugar. Seems processing sugar and fats had become an issue, but maybe that will be in the past now?

I really hate having to find a restroom all the time blankstare what can I say, sometimes a bush just isn't near hmm

 

You're doing great, If you used to jog then ease yourself back into it, (after the smoke clears) ...hey, we should be getting our "good news" right about the same time in January...hang in there biggrin

bb, Iris



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



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Lamassu thats great! I might try getting back to 20-30 minute morning jogs during my break between jobs. I used to love jogging! maybe thats what my body needs - vigorous exercise. 



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Hi Hoodie,

For me the heavy fatigue ended like magic after week 10 on Epclusa. Seems like it was overnight. Now my stamina was lousy because I had gotten little exercise for over 2 months but 6 months after end of treatment now I am feeling pretty good, and walk every day as much as my bad right knee can handle. Probably will get the knee replaced next year as I have had enough medical treatment for one year:) I still drink at least a half gallon of water a day. May not be medically necessary any longer but I feel better when I stay well hydrated. Just waiting on the 24 week viral load results from the test done last week. Everyone's journey is different I have no doubt any lingering fatigue you have will pass. Take good care of yourself!



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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.



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5-1-18 wrote:

my first 2 months eot i drank more, now it's about 1.5 liter plus watery coffee. 

i drink more on my days off i think.


Thanks 5!

Hows your energy? Is it better on the days when you drink more water? Refresh my memory, did you have horrible fatigue like me? Hope youre feeling much better now in EOT UND-land



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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my first 2 months eot i drank more, now it's about 1.5 liter plus watery coffee. 

i drink more on my days off i think.



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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Polo - Many thanks birthday girl

Shemp - Thanks Champ!

Cheddy - Fatigue is still an issue, along with anxiety/PTSD. My stress tolerance has been notoriously low for the past few decades. It is my fervent hope that my stress tolerance will improve. I think I see signs of that but of course my head messes with me and tells me Im crazy. Im just going to continue getting the right amount of sleep, proper nutrition, and especially yoga/meditation.

Everyone - I have totally slacked off on the gallon a day thing! So today I have renewed my practice of keeping track of my water intake to try to reach at least half a gallon if not more every day. What do you guys do? Do you still drink a gallon of water a day after treatment ends? Do you still track your water intake? Im going to try to get in a full gallon a day again until my January blood work for SVR12.  

As usual, thank you so much for your care and concern



-- Edited by Hoodietree on Sunday 18th of November 2018 10:27:06 PM

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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Congratulations Hoodie!! Welcome to Club Zero with that UND status, WOW!! Another wow that you start a new job with a good company..WTG and good for you girl for taking care of you! Your quality of life is already improving with UND. A Happy Thanksgiving and Happy Birthday for sure!! Hooray, Hoorah!! Yippers!biggrinbiggrinbiggrinbiggrin

A 10 day vacation between jobs is the only way to fly...biggrinbiggrin

ps



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Female,1a,F2 mod fibrosis,HCV 06/2017,SOT 08/04/2017, Harvoni

HCV VL 414,000, AST 54, ALT 74.  4 weeks AST 34 and ALT 31, VL 4/8/12 weeks - UND, 90 day SVR, Jan 2018. 

12 week EOT, AST 20 & ALT 23 and still VL UND at 13 weeks and 6 months!

Club Zero Member.

PoloSilver



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Hey Hoodie,

Congrats on EOT and of course UNDETECTED.The word kind of stuns you at first,takes a while to sink in.And,congrats on your new job!If treatment teaches us anything,it's that nothing is imposible.You have an amazing attitude and outlook on life,and I know you'll do well no matter what you choose to do.It's great you have some time between jobs.Rest up,regroup,relax.Then,you can begin writing the next chapter of your life.I'm sure it will be great.



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62 yo male GT 1b/2 ALT 60 AST 51 V/L 985,000 Fibro A2 F 3/4 began 12 wks Mavyret 9/13/2018

6 wk labs ALT 12 AST 18 V/L NOT DETECTED EOT 12/05/2018 NOT DETECTED



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How are feeling post treatment so far? Any improvement with fatigue?



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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Yup, me too, was wondering (but kinda expecting) that very nice EOT UND! Congrats! We can hardly keep up with all your good, "new" news! smile C. 



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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Hi Hoodietree,

I was wondering about you congrats on undetected at EOT!



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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.

Tig


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Hoodster,

How absolutely wonderful to hear your EOT viral load was zippity, nada, nothing! "Undetected" will forever be a word that holds special meaning. It does for all of us and I know that SVR will also prove true for you. I'm feeling it!

Ride out your last days with Company A with a smile on your face and the knowledge of great days ahead with Company B. I know you're going to do well, just look at how successful you are right now! Much to be thankful for, no question about that. You're winning and will continue to. After your probationary period and promotion to manager, combined with successful treatment and SVR, life is going to continue to improve in ways you only dreamed of 6 months ago. That's what hard work and a positive attitude will get you!

Woot!!

 



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62 yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 1-4 years!

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Image result for happy dance gifs



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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Iris, for sure the air quality here is very bad, but I dont seem to be too terribly affected by it. its just a little depressing thats all, knowing that people are suffering so much.

Cheddy, thanks for checking on me Cheddy. I gave two weeks notice at my current job so my last day there is 11/27. My new job starts December 10,  so that gives me 12 days off between jobs, yay! And yes I totally have imposter syndrome! But I know its going to be fine. The company is super profitable and its employee culture is renowned. But its the big time so Ill definitely need to perform in order to be promoted to manager in 6 months, which is what I interviewed for. They were nervous about hiring me directly into that role, so they hired me as an individual contributor with the expectation that I will be promoted in six months. To be honest Ill be happy either way.

Canuck, sorry I forgot to update you all! I did get the results of my viral load and they verbally told me over the phone that its undetected. Come January Ill get confirmation of that and then we will all do a big happy dance together!



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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I imagine she is being affected by the smoke from the Camp Fire, there in the bay area. Saw a pic of the bridge disappearing into the smoke. no



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



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How are you feeling Hoodie?  Any changes?  How are your nerves holding up?  

You are going to be so freaking thrilled!  I just know it.

How the new job?  I remember when I started a new job, I would freak out thinking, "Oh my god. Why did I say I could do this?!"  2 weeks later I would be be saying, "What was that all about?" 

Well, I hope all is well and improving.  I don't think you will settle or less.

 



__________________

GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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Hoodie,

It's getting to be almost a couple weeks ago you were getting the EOT labs you requested, your ALT and AST came back, nice and lovely and low (10 and 13), but what ever happened to the VL results?? uh, did I miss it, on another thread?? confuse C.



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Ya lamassu - I loved best of all, the studies where they showed 100% of certain sectors of us good folk gettin all cured up with Epclusa! wink C.

 



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Hi Hoodietree,

For Epclusa I got the overall 99% cure rate for GT2 and 95% for GT3 from this reference on PubMed. You can read the entire article at the NEJM here. For a wealth of knowledge about HCV I refer to the course modules at Hepatitis C Online at uw.edu.

Note that in the ASTRAL-3 (Epclusa) study of the 231 GT3 patients without NS5A resistance associated variants at baseline, 225 (97%) had a sustained virologic response.

Don't fret I'm confident you are cured and you should be also. Because Epclusa is so successful across all genotypes testing for NS5A resistance before starting treatment is not the standard of care for patients with GT3 at present. Vosevi is never initially used for treatment naive patients but held in reserve for patients who have previously been treated with a Hep C regimen containing an NS5A inhibitor like Epclusa and do not achieve SVR12.



-- Edited by lamassu on Saturday 27th of October 2018 12:16:26 PM

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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.



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Definitely keeping my fingers crossed for you, I wonder why that "what if's" sneek in. I'm with ya...worries like this do plague me as well. Keep the faith. Does your 12 mo fall in December or January? Probably January huh?

Blessings, Iris



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in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)



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You guys, THANKS!!

Don't have VL numbers yet but AST is 13 and ALT is 10. All signs point to CURED. Sorry for the freak out will update you with VL number ASAP!

Mwah!

canuck:

Read ALL the study stats, 93-97% for people taking Epclusa - we are right up there! wink C.

didnt know that! Someone was saying GT3s can be resistant and if course I took that and ran wild with it, heh.  Then the nurse said "false hope" and I ran wild with that too. All good, I'm gonna be fine  



-- Edited by Hoodietree on Friday 26th of October 2018 11:10:59 AM

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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Hey Hoodie,

Good for you in persisting (about getting them to agree to doing your EOT VL and LFT's) even if those labs will be drawn a little later than your actual EOT date.

Your 4 week VL and LFT's were a bit late also (at week 6ish?, or so, I can't recall right this very second), but ... being that ...

(1) you got Epclusa (phht your cure is a done deal!), and ...

(2) that you have already gone UND ...

I am sure you are still und, and will be, forever more.

So, your question was ... what? ... do you know what my odds are by any chance? ". Um ... (in my book) you have already been cured, the wait for the EOT+12 week labs is a mere but important technicality to prove your SVR 12.

Having this additional VL UND and labs under your belt at EOT will make you feel better about things.

That's a couple times now you have thrown around this dismal low percentage of cures for GT3's, it just not accurate, maybe back in the interferon days, I tried to counter it before, but to no avail, we 3's (nowadays, with the likes of epclusa and all our lovely new DAA's) are not much different a population to cure, NOT as difficult to cure, in fact, we are now boasting extremely high cure rates, much like everyone else. Read ALL the study stats, 93-97% for people taking Epclusa - we are right up there! wink C.



-- Edited by Canuck on Saturday 27th of October 2018 12:04:55 AM

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HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 63 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)



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Oh yeah, I hear you Hoodie.  

Nothing is quite enough until you get that SVR12.  Even the EOT viral load can still leave a gap. It's hard to help it when the treatment has been so long and laborious.  Every step bares some kind of anxiety - being diagnosed, deciding on treatment, getting coverage, getting treatment, waiting for test results, let alone the crazies. No wonder we build character.

The process is the same: hang in there and wait for the science to show you.

I don't have diagnostic powers, but I would find it really hard to believe that you are not at the end of this road, in part because the treatments are sooo good and because you have persevered mightily.

I have always been surprised that you managed to go to work through all the side affects. You've also held such a good attitude for others, showing your true optimism.

Can you stop second guessing for a little longer, one hour at a time?

Just keep rocking it, girlfriend. I have faith in you.

 

 



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GT2a, VL 681,500, Less than F1, Treatment Naive

12 wks Sovaldi/Ribavirin, SOT 2/25/16, EOT 5/17/16

UND at 2,4,8 and 12 wks during treatment but ribavirin crazy.

ALT/AST normal EOT

SVR12 8/13/2016!!!!!!!!!  I WON!!

EOT 6 Months 11/12/2016  CURED

 



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hoodie, yep that little nagging fear is there cos we waited so long cry, and our hopes are so high.

i worried too. nobody here wants more treatment for you either, so we are sending thots and prayers to your blood as it goes thru it's testing that it is UND.:

 



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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I'm so happy for you and it really gives me hope so THANKS

Pretty new profile pic too!!



-- Edited by Hoodietree on Thursday 25th of October 2018 10:32:07 PM

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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Hoodie try not to worry. I know its hard but Miracles do Happen. The only test that matters in SVR 12 so hang in there. Epclusa is the real deal even for us gen 3's. sun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gifsun.gif

cant tell I'm happy today can you. wink.gif

 



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND



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Thanks y'all. I'm freaking out a little to be honest. What do you suppose the chances are that I won't be cured? Like does GT3 have an 80% cure rate? Instead of 90%? 

Lamassu do you have the actual numbers by any chance?

> The worst that could happen to you is that if the virus is still detectable at EOT + 12 weeks you would have to go another round of treatment with Vosevi.

 

I super don't want that though  

Canuck if you're reading, do you know what my odds are by any chance?

 



-- Edited by Hoodietree on Thursday 25th of October 2018 10:20:01 PM

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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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hoodie yes i am praying for you. you will be joining the UND of us



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Gt:1a-36yrs .Started Intron-A in 96' for 2.5mo-VL still too high.taken off. Labs on 3.6.18:. A1 activity.  f3@60: fibrosur bloodtst. AFP=norm. enz=mostly norm.VL=3.9 million.sot=5.1.18>Harvoni>[8wks]: 4WEEKS=UND. Eot 6/25=L.July=norm liverpanel.13weeks=UND + 6 months =UND: CLUB ZERO



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Hi Hoodietree,

Glad you got my note and are having the tests done right away. My prayers that you are undetectable right now.

You are young and have a very low F score which is great news. The worst that could happen to you is that if the virus is still detectable at EOT + 12 weeks you would have to go another round of treatment with Vosevi. That could happen to any of us. The difference between you and me is that I am Genotype 2 which has the highest cure rate with Epclusa while you are the tougher to treat Genotype 3.



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Male, 65, Dx 1990, GT 2a/2c. Pre-tx VL 11,500,000, ALT 10, AST 18, F3, 12.4 kPa. Rx: 12 weeks Epclusa, SOT 3/8/18, EOT 5/30/18. Week 2 VL 50, ALT 12, AST 21. Week 10 VL not detected, ALT 12, AST 18. EOT + 12 weeks: VL not detected, ALT 11, AST 19. EOT + 24 weeks VL not detected, ALT 9, AST 24.



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Update! just got off the phone with the nurse. She ordered the liver function test as well as a viral load.   I think I'll go get it done today

She also said that she didn't want to give me any false hope, because she said that it doesn't even matter what the results are right now, it only matters what the results are in 12 weeks. Aargh

Oh well I think I'll be fine? Pray for me please



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Lamassu thanks for the info!! I will follow up with them right now And keep you in the loop on my progress. Really appreciate your care and concern

Hoodietree,

Its your body and your peace of mind, just tell your doc to quit screwing around and write you the damn lab order for a viral load and LFTs. As long as your insurance covers the cost I would expect your doc to be more receptive and caring. You could remind him/her it is the standard of care to check viral load and LFTs at end of treatment with Epclusa, and then again at EOT + 12 weeks. Especially for GT3 patients.

I don't mean to be a "Debbie Downer" here but you are Genotype 3 and while Epclusa is the best first choice for treatment naive HCV patients with GT3 according to the Astral 3 study the cure percentage at 12 weeks post treatment is lower than other genotypes depending on whether or not you are NS5A resistant.

Please don't stress out about this (I am sure you are cured!) but I would think you need the EOT viral load plus the EOT + 12 week follow up to confirm you are cured. In the rare event you are not HCV undetectable at EOT + 12 weeks you have the evidence to prove to your insurance carrier that they need to cover an additional round of treatment with Vosevi. Again, please don't stress out. I just want you to receive the best care possible.

 

 



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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Thank you so much for all the well wishes and congrats everyone. You guys truly are the greatest support EVER!

Just to give you a little background on the "Appaloosa"my iPhone AutoCorrect's Epclusa to Appaloosa so that's how it got its name. It's a little "in joke" with me and my sister

Lamasu - I read a post by you in a different thread where you said that you had a hard time for the first 10 weeks. Well that was my experience as well the first 10 weeks were filled with fatigue and weirdness especially brain fog. When that lifted I was in a state of transition and probably should've scaled back on my coffee because I no longer needed it as much. But I was still drinking the same amount of coffee and had a ton of anxiety! Live and learn Now that I'm done with the Appaloosa I'll just have to wait and see when my energy levels out to a more steady state. Definitely can't drink as much coffee without experiencing a ton of anxiety now that the fatigue is lifting.  Curious to see when other good things start being possible, like clearer thinking for one. Maybe that will come when I start hiking again looking forward to that!



-- Edited by Hoodietree on Friday 19th of October 2018 07:35:55 PM

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F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 



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Congratulations Hoodie!!!!!!!!!!!! WOW, a major milestone has been reached, you did it. I love those little ponies, they look so happy! The way we are all supposed to be, kick up your hooves and smile!

 

ps



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Female,1a,F2 mod fibrosis,HCV 06/2017,SOT 08/04/2017, Harvoni

HCV VL 414,000, AST 54, ALT 74.  4 weeks AST 34 and ALT 31, VL 4/8/12 weeks - UND, 90 day SVR, Jan 2018. 

12 week EOT, AST 20 & ALT 23 and still VL UND at 13 weeks and 6 months!

Club Zero Member.

PoloSilver



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 EOT ......Wow Hoodie. On ya. Bet you thought this day would never come. I know it was exciting, to know I had made the finish line, yet daunting to no longer have to focus on taking my magic bean every morning. Soon got over it though.



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66/F Contracted Early 80's First Diagnosed Early 2000's 2017 re diagnosis and referral for treatment Gen 3a Fibroscan 8.7

Epclusa 12 weeks commenced 1 May 2018 ALT 72 AST 67

28 May 2018 4 weeks ALT 16 AST 23 ...... 23 July 2018 EOT ALT 23 AST 30 .....Oct 16 2018 SVR12 UND

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