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Post Info TOPIC: For those with Riba Rage. Who can't get along with their loved ones


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wow all I can say is welcome to my world. I got 2 shots left & then whatever pills are left. things got realllly bad today with son's eife again towards my mom. then my 1st cousin died, then my car broke down. I hope this has cured me cuz I am NOT doing riba or interferon ever ever ever again. it takes it toll on ppls body!! so I am there with all of ya's.. but we got to hang tough.. somehow! smilefurious



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TazKat Genotype 1A null responder x 3 riba & iterferon twice, relapsed from Incivek 2012 with only 12 weeks left to do. stage 4 mild cirrhosis 4/25/2014/ started sovaldi riba & interferon.. finished treatment 7/17/14  results 7/25  cleared..

 

 



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I also went to an AA meeting this morning - it works under all conditions!

 



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 



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Yes, I am grateful that now I know that the meds are complicating my situation, because I was beginning to wonder what was wrong with me. I went to an AA meeting this morning and now I feel much better. My perspective is much more clear. I think that I need to keep myself in meetings and church so that I can keep infusing my mind with words of hope and positive ideas. Thanks guys for your words of wisdom.



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DJ...dx 2005...geno 4c...twice interferon/riba failure....completed 24 weeks Sovaldi & Riba on 10/18/14....SOT VL 600,000 after 16 days VL <43. Day 45 <43 again. Day 59...8 weeks UNDETECTED.

Happy and grateful to God for new life....



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what helped alot with me is I had something to blame it on -  I knew it was the medicine. 



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 

Tig


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Hi Debra,

Sorry about all the emotions, but you're right, it's the meds talking. I'm not sure how much is related to the Sovaldi, but I'm sure you're experiencing side effects from the Ribavirin. It's well known for causing anxiety and increasing your level of intolerance. We refer to it here as "Riba Rage". Some people escape it but the majority of us have more than one story about the ugliness it has brought to our lives. Do you best to avoid the people and situations that trigger these episodes. If they are really out of control, tell your health care team about it. There are some things they can try, but I believe knowing what is causing these episodes and avoiding them, your best line of defense. Good luck...

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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It never occurred to me that it was the meds that was making me "other than myself." Since my mom has had some serious health issues and my life has been interrupted by going back and forth from NY to SC to see about her, I thought my depression, anxiety and overall short fuse was contributed to that. However, I've had many tough issues in life that I've had to deal with, and I've always been a soldier of hope. Now though, I am intolerable of almost everything and my new name could be Negative Nellie. I'm glad that I realized that this insanity is being promoted by the meds. I rarely get a good nights sleep, which doesn't help the situation. Today is day 56 of the 6 month regimen of sovaldi and ribavirin. 1/3 of the way there. I pray to God to keep my mind focused on Him. "I can do all things through Christ who strengthens me." Philippians 4:13



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DJ...dx 2005...geno 4c...twice interferon/riba failure....completed 24 weeks Sovaldi & Riba on 10/18/14....SOT VL 600,000 after 16 days VL <43. Day 45 <43 again. Day 59...8 weeks UNDETECTED.

Happy and grateful to God for new life....



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OMG Tig ..... You got me again! Ha ha ha Hows the tea?

I came home last night, my husband took one look at me and said. "why don't I go pick you up a Greek Salad for dinner" .... He's catching on pretty quick. Survival technique I'm sure.

On a happy note, I just put the final week of incevik into my little pill container. Last week of prying those stupid purple pills out of those impossible to open blister packs! One. More. Week .... (plus one dose.. Duh)!

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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.



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Good to hear!! See, things are already starting to look up! You will make it through, no problem!! :)

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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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It has been a long and trying weekend/week, but it seems like we're starting to pull through it.  Great advice from everyone, and we will be looking into a good psych on top of everything else.

Biggest news though....just got our labs back and WE ARE BOTH UNDETECTED!  Also. No changes in the blood panels either, so no anemia or anything even starting to look out of whack!

Thank God for this, and many prayers for everyone enduring and fighting the same battle!!!!!



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Me, Age 33 * Hep C+ in 2011 via IV Drug Use w/my Husband * Genotype 3A * 770,785 Viral Load * Hubby Layne Age 39 * Hep C + in 2010 via tattoo in Thailand * Genotype 3A * 3,185,000 Viral Load * 24 Week Sovaldi/Ribavirin Started February 21st, 2014!

 



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dustbear wrote:
It's been 10 weeks since I finished treatment. The riba rage left pretty fast, but reared its ugly head on 2 occasions for no reason at all. I have cut back on the Citalopram from 40mg down to 10mg.
I didn't take any ADs during treatment, but for year & a half post tx I've had some issues that I finally sought relief from.  Just last week I started with 10mg Citalopram, which I've already seen benefit from.   Downside is that sleep is more 'complicated' to achieve, but that's partly due to my dr dropping my Ambien dosage from 10mb to 5, right before my recent refill.  <shrug>

 



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

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Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 

Tig


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I'm glad that I had all of you to share this with! I'm also glad that you had a good laugh. God knows we all need a good gut buster once in awhile! One more thing to finish this little Riba chapter out for me. It just so happens that my wife and I were sitting here this evening and she got up, walked into the laundry/pantry room looking for dinner ideas. I couldn't help but think about those damn potatoes because I heard her open that cupboard door. I was in the middle of taking a drink of iced tea and wouldn't you know it, she asks me, "Where's that box of mashed potatoes?" I promptly started laughing and blew iced tea out of my nose! All I can say is "damn potatoes..."

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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I just read this post and and Tig... You got me laughing so hard, the tears started. It's so true to what I've been going through. I just can't seem to put things away anymore, it's just too much effort. Nothing fits, and if the sweater doesn't go instantly in the drawer, it's gets thrown across the room. If the cereal box won't close easily, it gets thrown in the cupboard open... No patience to be had here at all! so glad you can all relate....these moods come out of nowhere!

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  1. Gracie

1A. Previously treated non responder Rebetron in 2000 And Incevik in 2014 with a breakthrough at week 12. Fibroscan 15.5. VL 6,000,000. Finished 24 weeks harvoni on Dec. 19, 2015. SVR. Latest Fibroscan 8.8.



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To answer your other question, which was how bad did it get....

Well at the time I was on a different combo, I was on Riba with Pegintron. I was crying daily and fighting with my mother, sister, and husband all of the time. I realize now that I was more sensitive because of the medications, but also realized that my husband needed to be more informed about what I was going through, and I needed to just stay the heck away from the other people that were driving me crazy with their own drama on a daily basis. Ain't nobody got time for that!! Now I am on Sovaldi with Riba and its not nearly as bad!! But like I said, sometimes I get a little impatient and annoyed! Not fun but it will all be worth it in the end! :)



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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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Miss Cara, yes my GI prescribed them to me. They totally understand how the Riba makes us have anxiety and irritable. I have a pretty good relationship with my nurses in that office and when I came in for a regular appointment, crying about how everyone/everything kept driving me crazy, they were like....here....take these lol. Its rare that I ever take them during the day anymore, I mostly take them at night to help me sleep. Otherwise I am up all night worrying and stressing about stuff. That way, I get a good nights sleep, helping to feel better (less irritable) the next day.  In the beginning I was allowed to take them "as needed," now the bottle says, "2 before bedtime." I actually have been taking 1 1/2 before bed to save a couple for those other times when I think they might be needed during the day. (family functions, longggg sporting events for kids, driving in traffic...shopping lol) They are highly addictive so its nothing to mess around with, so I understand why doctors are weird about handing them out to everyone. If you are honest about the way you guys have been feeling, they should have no problem prescribing them to you. I felt weird about asking for that first refill but once I did, they were totally cool about it. Guess all doctors/nurses are different though so good luck!!



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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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aprileee wrote:

Oh my Tig. Lol..too funny. I know exactly how that goes! The other day i was doing some shopping at Old Navy and it seemed like every time i tried to look through the rack to find my size, the tags got all tangled up together, or i knocked half of the shirts off of the rack. Then i was trying on sunglasses and dropped about 4 pair onto the floor. When the woman who worked there asked someone else who was standing right next to me if she needed any help, even though i was there first, i about lost it, set all of my items down and walked out! Ugh! Its always everyone else, never me. Lol i had better luck at kohls the next day anyway...maybe because i took a xanax before i left the house! I doubt this would be considered a manic episode, but i know its the Riba making me a little crazy! Hang in there guys!! Sure makes me feel better to know that i'm not alone in this battle!! Thank you :)


 Aprileee-- Who prescribed you the Xanax, and how bad did things get before they did so?  My husband and I both have some mental health issues (no, we're not crazy wink), but all of our past health records were lost in California & so we have no proof of ever taking it.  It seems as though this area is very uptight and suspicious when it comes to prescribing benzo's (and good luck with any opiates, not that we want or need them, ever again). Would a GI even be able to do this?  

This is all new to us, so any info would be great!



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Me, Age 33 * Hep C+ in 2011 via IV Drug Use w/my Husband * Genotype 3A * 770,785 Viral Load * Hubby Layne Age 39 * Hep C + in 2010 via tattoo in Thailand * Genotype 3A * 3,185,000 Viral Load * 24 Week Sovaldi/Ribavirin Started February 21st, 2014!

 



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Tig, I was laughing so hard I was crying, man that must have been one heck of a crime scene, Mr Potato Head  has put you to the top of his hit list for sure!!

But it goes to show how fast we can go from zero to 100 M.P.H.    It dosent take much, knowing this I try my best to feel  the riba shake coming and try to time out.  RC



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   



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Oh my Tig. Lol..too funny. I know exactly how that goes! The other day i was doing some shopping at Old Navy and it seemed like every time i tried to look through the rack to find my size, the tags got all tangled up together, or i knocked half of the shirts off of the rack. Then i was trying on sunglasses and dropped about 4 pair onto the floor. When the woman who worked there asked someone else who was standing right next to me if she needed any help, even though i was there first, i about lost it, set all of my items down and walked out! Ugh! Its always everyone else, never me. Lol i had better luck at kohls the next day anyway...maybe because i took a xanax before i left the house! I doubt this would be considered a manic episode, but i know its the Riba making me a little crazy! Hang in there guys!! Sure makes me feel better to know that i'm not alone in this battle!! Thank you :)

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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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My turn to fall on the floor laughing thinking about you giving a box of mash potato what for...bet it won't do it again...priceless biggrin. Perhaps food labels should have a RIBA rating so you know what your letting yourself in for and what dangers could lurk in closed cupboards....



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51 year old Geno type 1A,  possibly 30 years HCV. HBV detected but currently dormant. viral load over 1,000,000. Started triple with Telaprevir Nov 2013 for 48 weeks.

VL week 4 -179,

VL week 12 -50. 

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Tig


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Hey RC,

You're absolutely right, Riba rage is most definitely real. I'm several months post treatment and I still have trouble with it. I notice more instantaneous anger, often for very little reason at all. I have to admit to everyone that today wasn't a good day at all. I've been noticing that irritation just bubbling below the surface all day and then it happened. I must admit it's funny right now but it's really just another example of the underlying issues this drug can cause and not really that funny. But I'll have to describe it and share what is now embarrassing but at the time was pure anger directed at that poor box. I went grocery shopping and when I came home I was putting stuff away. Well there was this box of instant mashed potatoes on the shelf. I put some stuff up there next to it and the potato box fell out onto the counter. I picked it up and put it back. (I'm irritated by then) As I started to close the door, the box fell out onto the counter again, spilling a small amount on the counter. I cleaned it up and put the box back in the cupboard again. (Now I'm really getting pissed). As I go to shut the door, something fell and hit that damn box, again knocking it onto the counter, for the last time. (More potato flakes went across the counter.) That was it for me.... I cussed that box out and told it if it wanted to keep falling out of the cupboard, I'd show it how it's done. I grabbed that box, thoroughly enraged now and threw it at the wall. I was standing inside my laundry room (picture this), an 8 X 10 ft room, washer/dryer, me and half a box of potato flakes exploded all over the machines, me, counter top, everywhere! By the time I finally got the vacuum out and cleaned it up, I was no longer angry, just embarrassed at how stupid it all was and how glad I was that nobody else got to see me do it (or hear the language I was using). This just isn't like me at all and I know what is likely the cause, Ribavirin and the need to rearrange that cabinet, lol. They claim it can take 6 months to totally clear out of your body once finished, and I believe it. It's nothing to take lightly and we are all wise to remember what it's capable of causing. PLEASE do yourself a favor, right now. Remove all boxes of instant mashed potato flakes in your house. They are particularly persistent and hard to clean up....  confusenowink

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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riba rage is real, im not on peg and 33 days into riba/sofosbuvir and its getting more noticeable. It seems the less sleep i get the more rage kickes in in the afternoons.Sleep and riba dont mix well, its like water and oil. they dont work well with each other.If i sleep 3.5 to 4 hours the rage is less.  and you seem to get stuped on this combo of drugs,  my wife is very understanding and puts me in check when i gey really bad. Im not complaining, im thankful for the chance to kill the hcv.and i cant spell very well now, it will  all get better after treatment    Im grateful for the combo im on, my numbers coming down    RC



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 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   

Tig


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Hi Miss Cara,

I'm sorry to hear that your husband had a bad experience like that. I'm not sure I'm able to answer your question as accurately as it needs to be but I do remember a post left this morning that dealt with the issue is some respect. I'll provide that link and if I find some additional information on the subject, I'll be sure to pass the data on to you. Be sure you mention these issues with your doctor too. These are difficult drugs for us all, your husband is very fortunate to have such a caring person by his side! As soon as this treatment is complete, those side effects should resolve fairly soon.

Tig

http://hepcfriends.activeboard.com/t56969729/information-on-hcv-trials-involving-people-with-co-morbid-me/?w_r=1394415708#lastPostAnchor

Google links on the subject:

Ribavirin and Bipolar Management



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Does anyone have any experience or education on hep c treatment for bi-polar individuals?  My husband has dealt with this for several years (the majority of it being strictly manic, no depression), but has done well controlling the moods over the last year or so without medication.  However, this past Friday, which marked 2 weeks for our Sovaldi/Ribavirin treatment, he had a manic episode unlike one I had ever seen.  It came out of no where and was really intense, but seems to have subsided since then.  It has us both really concerned and not sure what to do.

Any ideas?



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Me, Age 33 * Hep C+ in 2011 via IV Drug Use w/my Husband * Genotype 3A * 770,785 Viral Load * Hubby Layne Age 39 * Hep C + in 2010 via tattoo in Thailand * Genotype 3A * 3,185,000 Viral Load * 24 Week Sovaldi/Ribavirin Started February 21st, 2014!

 

Tig


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Cara,

I had a terrible time with the scalp dryness, blistering and burning. It was awful and I'm still having mild problems with it 3 months post treatment! During treatment, I used a liquid OTC product called "Scalpicin". It's a 1% hydrocortisone solution and it helps the itching a lot. My doc approved it by the way. Be careful you cover your head when you're in the sun. Here in Florida the sun is a constant and exposure to it an exacerbate any current skin problems. Keep a good quality, unscented skin cream close by and keep your skin moist at all times. It will reduce the itching too. If you have a low Hgb, that may be responsible for at least part of your muscle cramping. You should also ensure that you are drinking enough water. Insufficient hydration and these meds can dehydrate you, will cause terrible cramps. They are often noticed more at night by the way! Try to drink 2-3 liters of good filtered water per day. Good luck...

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Cara -   You might have to resort to a corticosteroid product for scalp/skin problems, if your doctor approves. They come in liquid solutions for the scalp, so it doesn't compromise the hair too badly. I've been using one called Clobetasol Propionate. It's helped greatly with the light rashes I've been getting. Just a thought... ;)

wayne



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66 y/o male - Geno 1b - F4 cirrhotic dx 2001 - 16 wk treatment w/ Sovaldi/Olysio/Riba - Und @ EOT+24 SVR

 



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aprileee wrote:

Mila thats pretty much how i feel too. I just avoid annoying places and/or people and remember that this is all happening for a good reason....and although it may not seem like it right now, i am becoming a better and stronger person through all of this. Just stay outta my way until july 9th! Lol :)


 

Cant sleep, again, and thumbing through some of the posts in here.  It sounds to me like we're floating in the same boat as far as the side effects.  One that I've been having, which I haven't seen yet on here, is cramping in my hands and feet--straight up charley horse style.  These are so not fun, especially when they show up just as soon as you finally fall asleep!  And I now have a severely dry and peeling scalp, which I've never experienced and is total pain with super long and thick black hair!



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Me, Age 33 * Hep C+ in 2011 via IV Drug Use w/my Husband * Genotype 3A * 770,785 Viral Load * Hubby Layne Age 39 * Hep C + in 2010 via tattoo in Thailand * Genotype 3A * 3,185,000 Viral Load * 24 Week Sovaldi/Ribavirin Started February 21st, 2014!

 

Tig


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Hi Mila,

While the Interferon does make you feel like anything but good, it isn't known as the cause for the "rage" we often refer to during this treatment. Ribavirin has a well known and unpleasant history of causing the episodes of anger and short tempered reactions to what normally wouldn't bother us. My experience with Interferon and Ribavirin has shown Interferon to be more responsible for the moodiness and depression, if there is any and Ribavirin for the anger and irritability. Some people are fortunate and make it through Interferon without the depression, but I think most people have at least one story about their temper getting the best of them while on the Ribavirin. Fortunately these side effects disappear in time following the end of treatment.

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Mila thats pretty much how i feel too. I just avoid annoying places and/or people and remember that this is all happening for a good reason....and although it may not seem like it right now, i am becoming a better and stronger person through all of this. Just stay outta my way until july 9th! Lol :)

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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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Aprilee... Everything I read seems to blame interferon for the rage, but the nurses I spoke with say other patients on Ribavirin have reported the same. However, I could swear that other people have just become unbearably annoying!!! It's either that, or I'm normally an absolute angel to be able to tolerate them. Right?

Like dustbear, I agree with your message, too! In fact, last night I wrote a rather long-winded and sappy comment about being positive under one of my original posts ("Hey! Everybody on Ribavirin + Sovaldi.") WHY do I go off on these manic rants? Is it the Ribavirin? I feel so jittery and "speedy" and my mind races sort of like I've had too much caffeine but am still really tired... 

 



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aprileee, I love your message! After all the whining I did I am so grateful to everyone here as well.

mila, i can so relate to the irritability! My hubby flicking his nails, just sitting on the couch, or any little thing would drive me crazy. I stayed home and away from friends, and actually walked out in the middle of a conversation! I almost hit my boss, and girlfriend. I was always the nice girl.

It's been 10 weeks since I finished treatment. The riba rage left pretty fast, but reared its ugly head on 2 occasions for no reason at all. I have cut back on the Citalopram from 40mg down to 10mg.



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Geno 1A, since 1981. SOT 1/2013   TX stopped 11/2013 in week 45/48 due to Myositis & Interstitial Lung Disease. Completed 94% of Peg-Inter dbl TX, UND since week 4.  SVR 4/2014!  Still SVR after 4+ yrs!

"Day by day, step by step, breath by breath"



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Thanks mila, you too! So it is the Riba then. I wish my nurses would start reading this stuff! And i know what you mean when you say you wanna kick people in the face. Luckily, i have not done anything like that although similar thoughts have crossed my mind lol. Im trying to just remain positive and think of all the good things and stop focusing on the bad, or extremely annoying!! Just walk away :) I have been meaning to hang this on my wall to see every morning to stay positive, just another corny facebook photo thats been passed around...i cannot post pics to this from my phone so i will type it out.... Thank you God My muscles are sore, but they work. I did not sleep well last night, but i did wake up. My wallet is not full,but my belly is. I may not have all i want, but i have all i need. My life is not perfect, but it is good. Love that, goodnight :)

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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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Hi Aprileee,

I also just started on Sovaldi & Ribavirin and, fortunately, live alone but have been downright nasty...especially to my closest friend who is always helping me. I was NOT like this on interferon. On Interferon I was far too sick and depressed to be mean, though. This is also not my normal way of being; people usually describe me as being "sweet."

I've asked my friends and family to understand, not take it personally, and not create more stress by reacting to me and to even allow me my melt-downs, if necessary--and I try to do my part by controlling myself as much as possible but also by always freely admitting when I'm feeling like I want to jump right out of my skin and kill something (or them for no apparent reason.) For example, last night just my friend breathing was annoying me while he was sitting on the bed by my feet and I had this crazy thought of wanting to kick him in the face really hard. Seriously! I told him exactly what craziness was going on in my head; he's so compassionate and understanding and patient... Anyway, I like to imagine that the rage is a pissed off dragon being slayed, and then just laugh at it.

Hang in there!



__________________

* Gen. 3a * Age 56 Relapsed in 1996 after 48 wks tx of 3M daily units alpha interferon *

24 wk Sovaldi/Ribavirin tx started Jan. 11, 2014 * VL 2.6M b4 tx Undetectable @ 2 weeks *



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I realize that this is an old post, but this really hits home for me.

During my last treatment with Peg and Riba, I was extremely irritable, anxious and cried A LOT. Now I am on the new Sovaldi with Riba and I still feel the same way, only no crying over stupid stuff...im a little stronger (maybe because im more experienced plus happy I don't have to do the shots anymore.) I had a hard time getting along with my husband, sister and mother during the first treatment but this time around my hubby understands what im going through a little better so I think he takes it easy on me now, lol. As far as my mother and sister I just stay away from them now because I think they are toxic to everyone...with or without treatment!

But what my original point was is that yesterday I went to see my nurse and she asked me how I was feeling on this new treatment and I told her, headaches...tired...irritable. She said, that's weird because the Riba shouldn't make me feel irritable...it was the Peg that did it to me the last time. I said oh, hmmm...and then came home and googled it and sure enough, all the websites say that irritability and anxiety are side effects. So what the heck is she talking about??? Some of you say that its a misunderstanding and that its the combo that causes the riba-rage, not the riba itself but I am sure feeling it! Or maybe its just this whole treatment in general, learning more about myself and my family, along with living a healthier lifestyle without smoking pot or drinking alcohol? As of right now I rely on taking my prescribed Xanax to get me through stressful days and to help me sleep at night otherwise I lay there thinking about all the things that could go wrong. Could also be this freezing cold weather that has us all cooped up for so long!

Either way, knowing that my husbands got my back now is a major improvement but I realize that not everyone has that...this forum has been a huge life saver. I have literally learned more from this than I have from my doctor and nurses and I don't even want to think about what kind of state of mind I would be in right now if it wasn't for all of you guys! Thank you so much!! :)



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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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Yes we will both be OK and will weather this storm with little problems. Her work has really taken a toll because of staff cut backs as well this time. In 05 I went through 72 weeks of this hell and it almost destroyed us, we also had to take care of her 91 year old mother for 3 years during the treatment and her bothers an sisters would do nothing to support their mother except demand there inheritances and she wasn't even dead yet. It was a very ugly time but we pulled through and strengthen our vows and love for each other. Fortunately she has very good support consoling that we have both used as a couple before. Well dart 47 tonight 13 1/2 days to go. Thank you all for your time to say kind words of encouragement. I am also blessed with that small handful of real friends that do many things for us.  What comes around goes around. Cheers 



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Don't sweat the small stuff, it will only give you hair loss.



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teddy,

 

if i remember correctly,you're at the tail end of 48 wks... just stay focused , think about the new life you'll have and consider yourself blessed & lucky to have the insight to make it to the end. obviously your wife  cares & loves you dearly for taking stress leave at work. now she gets to see you raw & untamed..... this tx does a number on relationships. it clearly shows you whether the other 1/2 will be w/you for the long haul. just give each other some space,reflect before responding to each other and maintain a level of trust & respect.

 

i recently left my bf of 11 years for he wasn't treating me w/dignity & respect during 2 1/2 mo. of tx. well my riba rage is now so under control and i'm remembering what a great happy person i used to be. for some strange reason i feel like a super hero for having the courage & strenght to do so.

 

remember to walk away  &  reflect prior to speaking during riba rage. don't lash out instead burn off the steam w/ a 15 minute walk.

 

sandy,ucbgal

 



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Hiya's

The first time is was on tx 2004 I had quit smoking for two years. In a fit of sleepless riba rage I grabbed a pack and started smoking again for four years. I've since quit again two years ago.

  Heres what I do now. First I concentrated on what it was like before tx. I keep this memory right up front and easy to reach. When I feel like I'm getting "a little testie" I step back into the pre-tx me and take controll like you would have to with a child. God knows with me taking care of my Mom who asks the same questions over and over I've had a lot of practice.

  Its like the story of the Knights shining and keeping watch over there armor in the chapel the night before the battle. Your the Knight (pre-tx) and your armor is the tx you.

 I hope every one finds SVR at the end of the quest. From what I've read some have even found the Grail traveling the treatment road.

Best wishes to all



__________________

Geno 1a null responder 2004 inter/riba   finished incivek,peg/riba 48 weeks May 17th 2014. undetect weeks 4-12-32.  EOT+7 undetect. EOT+24 SVR!!!!! EOT+!YEAR SVR!!!!



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Teddy, I here ya,

The riba/interferon mental sx are strong and wreak havoc on relationships. My husband is so burned out on my treatment, he pretty much ignores me when I talk about any feelings I have now. I keep having to remind myself to keep my expectations low and remember he's had to listen to my BS this whole time and try to be nice to me. I hope this hasn't done any lasting damage.

All my friends stopped calling about 10 weeks ago. Seems the only people that understand are people on here and my NP>

I'm sick of being ****ty, thinking ****ty and feeling ****ty. grrrrrrrrrrr......furious

keep going teddy, you can do it. Not too much longer. Just a few more days....

In the end it will be just a memory.



__________________

HCV 1A 1980. Dual tx 2003 -UND at wk 11-discontinued due to severe depression

Started Triple 4/16/13 for 24 weeks

UND wk 4,6,8,12,17 & 24

E.O.T. 9/29/13

EOT + 12 weeks=SVR, and EOT +26 weeks=Cured!



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My wonderful wife has suffered greatly from taking care of me and working a  abusive job. She finally crashed and is on stress leave for a month and it has gotten very hard on the both of us living together all day and being so sick with this treatment and her poor mental health we will pull through I'm sure. I will have to have rotor cuff surgery after I recuperate from the sides of the treatment. I hope by Next Summer things will be normal again. 



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Yes, Dominique, that`s a good point, and I`ve read that too.  I should think it`s very likely to be the Peg/Riba combo which causes most of the problems with extreme irritability and anger, along with other sx like fatigue, but I guess `Riba rage` is the most generalised and well known term for it.  Going through any type of Hep C treatment can be a stressful and worrying time for most people, and that in itself can cause irritation and anxiety.

Jack, I really feel for you and your wife.  A long stretch of 48 weeks treatment is bound to put a big strain on even the most solid of relationships.  Thank goodness you`re almost at the end of this at last, and you and your wife will soon be able to recover and heal together.  Keep believing that good times are ahead for you both...you`ll pull through this and be even stronger because of what you`ve shared.

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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I read somewhere that riba rage is a misunderstanding and that it is Interferon mixed with Riba which makes people nervous and depressed ?

I had Riba without Interferon and had no rage at all, but did feel depressed for good reasons.

I must add I am a calm and cheerful personn naturally, so may be it helps. But I did ask people around me who were on Gilead and Abbvie with Riba and without Interferon and they did not experiment rage neither.

Jack, sure you will both put through and even love one another more after this rough time. Courage smile

Do



-- Edited by ios9 on Tuesday 1st of October 2013 06:56:16 AM



-- Edited by ios9 on Tuesday 1st of October 2013 03:47:18 PM

__________________

Geno 1b. VL 17. M. AbbVie Turquoise II. UND EOT 4. 8. 12. SVR.

"Our task must be to free ourselves by widening our circle of compassion to embrace all living creatures and the whole of nature and its beauty."Albert Einstein

 

 

 



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Loopy Lisa wrote:

Why do some peope get Riba rage and others nothing? I am interested in this because I will have to take the nasty stuff!


Hi Lisa, I think it`s just that people have different reactions to Ribavirin, and in fact the same applies to all the treatment drugs.  Some people are lucky enough to have very few side effects, including Riba rage, whereas for others it becomes a more severe problem.  Younger people tend to do better with the sx, generally speaking, and I suspect there are other factors too, for example your own personal situation and how much stress you already have in your life.  With any luck you`ll be fine and have an easy time of it!  smile



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Why do some peope get Riba rage and others nothing? I am interested in this because I will have to take the nasty stuff!



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Genotype: 3b

VL.�over 15, 000 000

Failed TX 2014: Interferon/Riba.

Cured using Sof/Dak combination.

I can eat cake again! <3 



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Hi Tracy,

'Riba rage' is the name we give to one of the unpleasant side effects of Ribavirin. The severity varies from person to person and is often not recognised by the patient.  It means being easily annoyed by trivial matters, often causing an angry, sarcastic response ( even violent).  Patients become intolerant of tiny matters that normally wouldn't worry them.  It often places a big strain on relationships. Once the patient realises Riba is the problem, they often can modify their behaviour, and avoid situations that could lead to confrontation. It rapidly subsides when treatment is finished. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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What is riba rage?blankstare



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Tracy Scanlon


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I WAS LUCKY THAT THIS TIME AROUND I KNEW IT WAS RIBA RAGE AND COULD HELP PUT IN IN CHECK.



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wow...couldn't have said it better myself!



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33 years old Genotype 3a NO luck with Peg & Riba in 2013 but am undetected after 2 weeks of Sovaldi with Riba 2014 :)



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i hear ya. i had yo up my dose of lexapr. and my boyfriend is always telling me im irritable.  and yeah, everyday i go to work somebody tells me "wow, you look tired..."  i take it as a nice way of saying" wow you look really ****ty"....im used to the constant bags under my eyes, i have to relize other people are not and take it with stride!



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genotype 1a

Started treatment 4/12/13 with ribavirin and peg-intron. Started Victrelis 6/19/13. (triple therapy)



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Me too, lol!

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Seriously?


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Yeah the rage has got me too...people are looking at me lately thinking....did she just say that?  Oh and people at work are asking me "are you ok...you look pale...you look tired...." DID I ASK YOU HOW I LOOK?  Do I care what your opinion is?  NO...so just leave me alone....these are my co workers...uneducated bunch of monkey's....lol  see what I mean?  And this is not me, I am the nice one, the happy one, the silly one....hope I come back...



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 geno 1, started peg and riba 7/5/13, now 29th day is vicrellis ***tonib VL started 6 million, after 5 weeks 374,000, after 8 weeks 150,000....the big test for VL is 9/27 at 12 weeks  TAKEN OFF THERAPY JUST NOT WORKING FOR ME...12 WEEKS STILL HAVE 9000 VL

Tig


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Here's a little information for those being treated with IFN based therapies. Rage and depression can be the result of any or all of the drugs currently being utilized in the triple drug treatment regimens.

http://ajp.psychiatryonline.org/data/Journals/AJP/927068/592.pdf.gif



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Thank God, I am not alone on this. I used to kid around about my BS level being low, but there are some days I cannot stand myself.

Thank you all for sharing your experiences with us.

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