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Post Info TOPIC: Started treatment Monday


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RE: Started treatment Monday
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Now at day 10 and feel fine.  The after effects of the pegasys were much less this week, and the orals don't seem to bother me at all.  Riba-600mg (3 x 200) twice a day, GS-7977 400 mg once a day.  I sleep fine, have a good appetite, and , uh , I forget the rest.  (LOL) Onward through the fog!!



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genotype 1a, viral count 7 M

7/12/12 started triple with GS-7977(400 mg 1/day), Peginterferon and Ribavirin  12 wk  trial

11/2012 no svr

12/10/13 new trial with sofosbuvir/ledispavir combo and riba12 wks

3/10/14 UND

3/16/15 still UND, and feeling great



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Great to hear you're doing so well. Early days though, takes a while for Peg and Riba to rear their ugly heads. Could be that the antiproteases are the culprits in our case, both with direct effects and potentiating the Peg and Riba. The antipolymerases may be much kinder.  Be interested to hear how you go, with Hb, WCC, platelets etc.



-- Edited by mallani on Friday 27th of July 2012 03:24:55 AM

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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Most likely 600mg (3x200mg) twice a day.



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All Done Poisoning the Dragon that Used to Poison Me

Genotype 1b  Incivek Combo



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Is that 1800 mg ribavirin twice a day?

And many find that the second day after the shot is the worst. That's sometimes the case for me, but the side effects are so variable.

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Type 1B - Unknown for 30 years, diagnosed September 2011, started treatment February 2012

8 weeks Incivik - stopped early due to rash.

Continuing Pegasys and Ribavirin until January 2013 - 48 weeks

Undetectable from week 4 --> present



Guru

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Scout wrote:

Good luck, hang tough.  it'll get better, then worst, then suck, then boring, then better, etc. Welcome to the world of the fog.


 This is it in a nutshell, welcome to being "on treatment".  



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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Good luck, hang tough.  it'll get better, then worst, then suck, then boring, then better, etc. Welcome to the world of the fog.



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Geno 1a, Viral load at 2 4, 8, 12 and 16  weeks, UND, Triple therapy Incevek done,   Peg & Riba Done, UND and making plans for the future!!



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Hello, Vern

I guess you'll be like so many of the rest of us. You just never know from hour to hour what sort of sideeffects you will be dealing with. Sometimes there will be several nice days in a row. Whole days. Then sometimes it will go back and forth a few times in one day. Good thing is you seem to be handling it OK.

And Rocky (forgot to look at your real name before I started this response),

I did the same thing with my injections, but I only moved it one day. The docs were fine with that, but they said I couldn't move it back. It had to stay that way. I hope your treatment works out smoothly, and the beatings are few.



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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!



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Hope it stays mild for you. I thought GS-7977 was going to be used without Pegasys?

I take my 5th shot on Thursday, Incivek and Riba. Having all the expected sides, but now much more dizziness when I stand up or get out of the truck. My nausua comes in waves, I can feel fine all morning, then it moves in like fog across a bay.



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Genotype 1a, IL 28 = CT  Interferon and riba 48 wks in 99, Daily Peg and Riba 18 months in 2007, Started Incivek, Peg, Riba 6/21/12. 4th stage cirrhosis. Last Dart will be May 23 2013.



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Monday I started my treatment.  Pegasys 180 ug weekly, 3-600 mg RBV am and pm, 1 400 mg GS-7977 each am for 12 wks.  They gave me a granola bar to eat, handed me the pills, then gave me the syringe and told me to do it.  Summoning up all my male courage I stabbed myself in the stomach, and was amazed that it didn't hurt at all. 

Monday really felt no effects at all.  Tuesday had joint aches, but was ok until the PM, then it felt like i was having fever and chills.  Crashed on the couch for a couple of hours, then felt fine.  Today, Wednesday, feel fine. No site reaction to the shot.

They are going to let me back my shot up a day each week until I get to Fridays

 



__________________

genotype 1a, viral count 7 M

7/12/12 started triple with GS-7977(400 mg 1/day), Peginterferon and Ribavirin  12 wk  trial

11/2012 no svr

12/10/13 new trial with sofosbuvir/ledispavir combo and riba12 wks

3/10/14 UND

3/16/15 still UND, and feeling great

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