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Hep C Discussion Forum -> On Treatment -> Weekly fluctuation of Sx
Post Info TOPIC: Weekly fluctuation of Sx
Fajah


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RE: Weekly fluctuation of Sx
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Post Incivek

Friday night shooter

Sat mostly ok till later in the afternoon...slugish and yucky

Sunday mostly slugish, Sunday night typical low grade fever some loss of voice, crupie

Monday - Friday     better to best and best is not so wonderful, but the high point

 

Incivek, a real crap shoot to include week to week variances

Fajah



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Fajah You know, the Father, Freaky Deaky Dutch

186,000 miles per second (299,792,458 meters/sec), not just a good idea, its the law.
Bloomster


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My husband takes his shot Monday evening and does feel extremely off for 2-3 days.  I think he is coping well though and has had minimal time off work.  So that has been great for keeping his routine going.

He is coming up for his week 12 blood tests on Friday, so it will be 2 more weeks on top of this until we find out if he is undetected.  We do feel confident, but it will be good to see the results in black and white as, you may or may not remember, my hubby's week 4 viral load test was rendered unusable due to machine malfunction. 

Glad to hear you're tracking along ok.  My hubby must be about 18-19 weeks behind you.



-- Edited by Bloomster on Wednesday 10th of October 2012 06:26:52 AM

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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014
kiwi


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yup. i was a thursday shooter (omg was omg) but friday, not too bad. sat sun, bleh. mon bleh... tues not bad, wed thurs starting to come right, then BAM, back to shot night... yup i sure did have a weekly cycle... my friends knew, i knew...

hang in there tho mate.

 



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kiwi. genotype 1. started pegasus and riba on 10 nov. VL 17.6 million. (4 weeks VL 1368)  week 15 UNDETECTED... :)
Phil G


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I was a Friday 5 pm shooter. Friday night was OK, generally busy and out and about, and turned in early. It started Saturday morning, initially around 10 am and got progressively earlier. It was over by Sunday noon. I kind of judge it by how much tylenol I took, typically 500 on Friday, 1500 on Saturday, 1000 on Sunday, and just occasionally during the week. The severity was unpredictable, sometimes fairly functional on Saturday, other times couch ridden. The frequency of naps alos increased throughout tx. That's the only thing I miss. 



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Geno 1A, VL 1.9 mm, SOT 12/2/11 - Pegintron/Ribavirin/Victrelis, UND since wk 8, EOT 6/15/12 (28 wks), SVR 11/30/12
gatekeep


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I also take the shot on weds. Thurs. good, Friday bad, sat., thought I was going to die due to the rectal trbl. Today Sunday like nothing ever happend. I feel it's a day by day thing . I hope after incivek is over things will improve.

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
hrsetrdr


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Malcolm,

I remember the cycle, Sat & San actually uneventful, but Mon thru Wed feeling like trash.

If anything at all was going to get acomplished that week, it would be on Thurs or Friday(before the shot).



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
news


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I noticed a weekly cycle right away, and blamed it on the shot. Like most of the others in this thread, I didn't feel the shot right away, but it crept up over the next two days. The funny thing is, and I have not heard others say anything about this, but the cycle slowly "mutated" from month to month, so I had weeks where shot day was good, bad and in between, and every other day of the week would change accordingly. It was a slow change in the pattern of the cycle. Kept life much more interesting.

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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!
country1960


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Same  here Mallani,, Do mine on wed. Dont hit till thursday night then feel like crap till tuesday, friday and sat seem t be the worse I'm in week 9



-- Edited by country1960 on Saturday 6th of October 2012 09:51:24 PM

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GENO 1A,  VL 600,000 DIAGNOSED 2007 PROBABLY INFECTED IN THE 80'S

UND @ 8 weeks!!! WEEK 12 STILL UND

doing triple tx Vict,peg, riba
Biggyb


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Same here..Take shot on Sundays about 3-4 pm..not bad Monday morning,,into the afternoon yuck..tuesday forget it. wednesday better, thursday still kinda yucky but can do stuff..friday pretty good, Saturday better..Sunday the best, then the shot and ready for Monday.....Gotta do this One day at a time...And dont think about how much longer i gotta do it or i get depressed.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~
mallani


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Does anyone else have a distinct weekly pattern in their Sx? Since about week 10, I am rubbish on Monday, Tuesday and Wednesday. I improve somewhat on Thurs., Fri., and Sat.  I presume this is Inter. related but not sure why ( we are supposed to have a fairly constant blood level). The severity of the Sx also varies from week to week. 4 weeks ago, Spring had arrived and I was generally feeling a bit better even on the bad days. However this week has been dreadful- on Tues. I stayed in bed all day and slept for 18 hours, and on Wed. I almost went to have an urgent Hb check. My head was spinning, severe headache, couldn't stand without support and short of breath at rest. I admitted to my wife that unless things changed, I was considering stopping Rx. Next day (Thurs) felt OK again. It really makes it extra difficult when you don't know what each day will bring. Suck it up, Malcolm.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
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