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Hep C Discussion Forum -> On Treatment -> Old injuries & Tx
Post Info TOPIC: Old injuries & Tx
Cinnamon Girl


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RE: Old injuries & Tx
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Oh goodness, sorry to hear this, Brian.  Did he advise you to rest it?  Take care and I hope the pain has eased up now, Jill xx



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
gatekeep


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Yesterday I went to my Vascular surgeon. He told me I have a acute varicose in a secondary vein. I was given a Heprine type x2 daily injection to thin out my blood. He can't see why treatment would cause this. Brian

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
Judy S


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Sorry to hear, Brian.  Glad you're feeling better today.  Yes, Vernon is right; I have noticed several issues that reared their heads during tx with Intron, Riba, & Vic.  Old injuries that I was able to manage for years felt like new ones.



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Geno 1a; VL 4.7 million in Feb 2012. Started PegIntron & Ribavirin 3-9-12. Added Victrelis 4-6-12. UND since Week 8. Stopped tx Wk 23. UND 4 Wks post-tx. Relapsed 12-weeks-post.

52 y/o F, started Epclusa 11-10-19, F0/F1.  EOT 2-1-2020. UND. All liver function tests normal.
gatekeep


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Spent 8 hrs at the emergency room last night because of the ankle. They told me I had cellulosic infection. I was given 2 antibiotics another ultrasound and complete blood count. I have been out of work for a week because I can't walk. Today I feel a bit better. My GI's NP called to say the infection swelling and high temp. Was all Tx related.

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
12Step Guy


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Doesn't treatment lower or compromise our immune system and make us more susceptible to all sorts of things? I assume that a variety of things that our immune system was containing will now be more forthcoming or noticeable? Could this explain why my normal aches and pains are worse?  



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Genotype 1a, IL 28 = CT  Interferon and riba 48 wks in 99, Daily Peg and Riba 18 months in 2007, Started Incivek, Peg, Riba 6/21/12. 4th stage cirrhosis. Last Dart will be May 23 2013.
gatekeep


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Went to My primary he got me right into a ultrasound. They didn't see any DVT but I have to get surgery on my secondary veins sooner rather then later. I've had flare ups before in this ankle but it usually goes back to normal over night. Right now I can barley walk due to pain. It's been three days.

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
mallani


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Hi Brian, I can't see how an old DVT would cause problems. However, anything is possible on these meds. For the last few weeks I've developed some swelling and pain in my hands and wrists. I've had to take my wedding ring off, and my watch is suddenly too tight. My albumen is normal so I'm not worried about it. See your doc if it gets worse, but really, nothing surprises me anymore about Sx. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
news


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Some swelling of the ankles is not uncommon in cases of liver disease. I noticed mine got worse and better, back and forth, during treatment. I also used surgical stockings at times, although I have not needed them since treatment ended. This is one of those things that should be reported to the doctors and monitored carefully, but not worried about (in my opinion). From where I am sitting yours looks like a perfect treatment, with obvious signs of response and effectiveness. I know you are miserable, but I'd be willing to bet you are getting well.

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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!
JoAnneh


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Those pains should hopefully calm down as you adjust to med, especially after u get past Invicek.
Try to rest ur ankle more than normal right now too. You are almost 1/2 way finished with Invicek.
Relief is coming just rembwred you are enduring this to prevent
Liver transplant etc.....
Rest as much as possible and drink lots of water
JoAnne



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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
Margo


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Interferon may cause unusual bleeding and bruising. Please inform your doctor so he stays on top of things.

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Geno 1b, relapsed in 2009 a week before my treatment was to be over. Started triple therapy on April 28th, 2012. UND at week 4,8,12,24,3 months post tx.
Cinnamon Girl


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Hi there Brian, I have seen people saying this sort of thing before, that tx has exacerbated old wounds and health problems.  It does seem to find our weakest points somehow.   Having said that, it would probably be a good idea to have it checked out just to make sure it`s all ok.  Are you doing or taking anything to help with the pain and swelling, apart from wearing the compression stocking?   Sorry you`ve got this to cope with as well as tx, hope it eases up.  All best, Jill xx



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
gatekeep


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I had a blood clot in my ankle 26 yrs ago. I've been on treatment now for 7 wks. I sometimes wear a compression stocking to help with the swelling. The past couple of days I've had unusual pain and swelling in the area where I've had trouble in the past. Will Tx make worst old injuries or bring forth old troubles?

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
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