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Hep C Discussion Forum -> On Treatment -> Missed dose
Post Info TOPIC: Missed dose
Bills


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RE: Missed dose
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Malcome please don't beat yourself up too much

I've seen lots of instances here where reductions in meds is absolutly necessary and quite a few missed doses  I think we'd see alot more breakthrough relapse If missing (a) dose would be that critical  Most of these people are UND and Post UND and SVR 

Ok? Bill S



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Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial  in Aug 2011 -July 2012 into Incivek relapsed  Feb 2013 Had 72 weeks on interferon & Riba.

hrsetrdr


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mallani wrote:

Thanks guys, appreciate the responses. This is when I find the Forum such a Godsend, as my wife really couldn't understand why I was so upset.

 Malcolm,    For all of us, the stakes are so high- we have alot riding on this treatment, not just for our physical health but we are pumped mentally & emotionally...I totally understand the feeling that some "minor" mistake could potentially derail months and months of effort and sacrifice.     

I don't think that there was any harm done, just the level of the poison in your system fluxuated a bit. 



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
js2012


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I use RXmindme on my iphone which is free app exactly for that but i have to travel across 7 hours time zone every few month which is completely messed up my schedule.  Took me a while to figure out how to calculate all the time difference.....and than again.

I cant imagine my life without all the stress of "can't forget to take my meds". Must be so different.



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Gyno a1, VL before start: 800K, F1-2

Started 48 weeks of Pegasys+Ribavirin+ Victrelis on July 6, 2012 

VL @8 weeks=UND

VL @24 weeks=UND

 
onabugeisha


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I worried that i had thrown up my riba and considered taking more.  But chose to wait.  I hope i did right.  I should set alarms also.  I have forgotten the pm dose up to 4 hours late.  I think after that many doses not missed you were probly still on track.



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     Gen2-diagnosed 2012  probly infected 1982   tx started 10-19-12   peg/riba  24 wks
JoAnneh


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Welcome to the rest of the Hep C clan Malcomb!
I missed Invicek dose which my doctor told me,
Never miss a dose; if your arm gets cut off
And it's between getting your medicine
Or your arm. Leave the arm, you can get another!
So like you I freaked when I missed a dose
And took it immediately! Alan helped me
Figure out what to do! I was panic!
We are all trying to do everything perfectly
As we don't want to blame ourselves
If tx fails.
I flex an hour every now and than on
RIBA. The RIBA company nurse suggest
I take RIBA at 8am and 4pm to help me sleep.
I didn't change I take it 12 hours apart.
I use mild sleep aid anyway:)
JRC sure saved you from future worry!
He missed dose and is SVR! Celebrate!
Xxoo, JoAnne




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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
Bouba


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Malcolm, just for your peace of mind (you surely know that). Its not that crucial as with Incivek being a shorter course and a higher importance of an intake interval.

A quote from Merck

If you miss a dose of VICTRELIS and it is less than 2 hours before the next dose, the missed dose should be skipped.

If you miss a dose of VICTRELIS and it is 2 or more hours before the next dose, take the missed dose with food.

      Take your next dose at your normal time and continue the normal dosing schedule.

 

You did right, no harm done. Keep well!

 



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58 yo male, HCV since 1981. Gen 1B (IL28B, CT). Diagnosed 1999,  VL before tx 100'000. Biopsy A2, F3 fibrosis. Naive, SOT (with Incivek) Oct 26, 2012. UND @ week 4, 12, 18, 24, UND 12 and 24 weeks post-RX
mallani


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Thanks guys, appreciate the responses. This is when I find the Forum such a Godsend, as my wife really couldn't understand why I was so upset.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
jrc


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Malcom i too missed a dose and had no issues, in fact twice i threw up a full dose instantly (Yuck). I was able to achieve SVR and im sure you will too.



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Geno 1 A Started Tx w/ Victrelis  8-3-11, Viral Load  21.2 Million,  Und Weeks 4 Through 28 ,End Of Tx 2-15-2012 !SVR
krowdog


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Oh, I know Malcom!  I was SOOO OCD about my doses, but I blew it too.

In fact I wasn't sure WHEN I screwed up...I just had 2 extra inciveks one morning.  I just took them right then and there, since that was the first I noticed the extras.

I then had the right amount, but 3 weeks later at the end of TX, I was 2 Inciveks short ??!!

I have a lot of respect for you 48 weekers.  It was all I could do to make 24.

Hang tough Malcom,

Brad



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(Geno 1a, Incivek Triple Tx, 6 month post TX - 9/20/2012 = SVR!!!)
Mary Jane


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Malcolm...It will be ok,  as the others said don't be so hard on yourself, you've had long journey my friend. I missed a dose the night I got my transfusion and I asked the Doc what to do, and she said just like your're doing try to make it up towards the end, but do NOT double up on the meds.. hang in there ..MJ



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Do not go where the path may lead, go instead where there is no path and leave a trail.Ralph Waldo Emerson

1a - VL 22 million  F2- IL28B- CT / Inck-Riba- Peg triple therapy 9/15/12 UND 4/8/14  8 wks BT ..3/1/2013 done! 3wks Post UND
Phil G


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Malcolm, I was also 3 hours late for one dose. And it was indeed panic waking up and trying to read the fine print instructions with those dried out eyes. If I remember right, if less than 4 hours late, take it and resume the regular schedule. So you were also late, but not missed. I am near certain that 99.9% compliant is going to be OK.



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Geno 1A, VL 1.9 mm, SOT 12/2/11 - Pegintron/Ribavirin/Victrelis, UND since wk 8, EOT 6/15/12 (28 wks), SVR 11/30/12
Shep


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Malcolm--please do not be so hard on yourself. You are doing fantastic. It's all brain fog

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Diagnosed 1996 genotype 1b VL alot tx starting 12/23/11 Victrelis UND week 8!!! 28 weeks of tx

Completed tx 7/6/12--still UND!!!!
Biggyb


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mallani wrote:
The Vict. and Riba pill load for 48 weekers is very difficult.

 Very difficult, i was about half hour late once on Vict. and 3 hours late once on Riba. I wouldnt really worry about it. You been doing really good .



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~
mallani


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Well, it had to happen! After 37 weeks of not being even 5 minutes late for a dose, I forgot my 3pm Victrelis. I have 2 alarms for the 7am and 11pm, but have got a bit casual about the 3pm. I discovered the error at 6pm and had sheer panic and disbelief! After gulping them down, I had to work out how to get back on track . Decided on Vict. at 1am, 8am, then back to 3pm. Easy to say I was watching an exciting end to the 2nd Cricket Test, but it a timely wakeup call. The Vict. and Riba pill load for 48 weekers is very difficult.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
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