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Hep C Discussion Forum -> On Treatment -> GenoSure Test
Post Info TOPIC: GenoSure Test
Caryn


Senior Member

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RE: GenoSure Test
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Thanks for your response Malcolm! I wonder why they would give me this test before treatment?  and congratheft getting to the finish line!



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1a, CT. Incivek triple 1/2013, vl 810 @ 2 weeks, 610 @ 4 weeks, 3000 @ 8 weeks, tx stopped. 

4/2014 - tx with Sovaldi/Olysio/Riba. VL 39 mil. - VL 230 @ 1 week, VL 40 @ 3 weeks, 5 weeks UND, EOT - UND, EOT @ 4 weeks UND, EOT @ 12 weeks UND!
mallani


Guru

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Posts: 3398
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Hi Caryn,

Labcorp have made this available and LanaiSurferGirl did a post about it some time back.

Basicly it is an assay to check mutations at the NS3/NS4a viral site. At the moment it only measures mutations against Victrelis and Incivek.

RAM's are Resistance Altered Mutations, and your test shows you do not have any, and that you are sensitive to both Victrelis and Incivek.

This will be the case for all patients unless they have had Rx with Victrelis or Incivek, so I'm not sure how useful it is. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
Caryn


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Posts: 305
Date:
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Has anyone had one of these done?  Here is a short summary of my results.  If anyone can explain, that would be great. This was a test done before I started treatment, but just posted to the labcorp website. 

 

PI
    Boceprevir      Victrelis    Sensitive

       NS3 RAMs*: None

       NS4A RAMs*: None
    Telaprevir      Incivek      Sensitive

       NS3 RAMs*: None
       NS4A RAMs*: None


__________________

1a, CT. Incivek triple 1/2013, vl 810 @ 2 weeks, 610 @ 4 weeks, 3000 @ 8 weeks, tx stopped. 

4/2014 - tx with Sovaldi/Olysio/Riba. VL 39 mil. - VL 230 @ 1 week, VL 40 @ 3 weeks, 5 weeks UND, EOT - UND, EOT @ 4 weeks UND, EOT @ 12 weeks UND!
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