Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> Clinical Trial Participants -> Side effect
Post Info TOPIC: Side effect
Biggyb


Guru

Status: Offline
Posts: 820
Date:
RE: Side effect
Permalink  
 

Great news Veronika, now the recovery process. You will now start to feel a little better every week...Good Luck !!



__________________

58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~
veronika


Member

Status: Offline
Posts: 8
Date:
Permalink  
 

Hi Suzi,

Thanks for your kind words.  I hope that your coordinator prediction becomes true. We will see. Please keep inform us about you. 

I very sympathize with the Merck compony working without making a big noise, may be there therapy will be the winner.

Veronika



__________________

Veronika

Infected with Hep C Genotype  1/b  may be 50 years ago from series of transfusion or working as a neonatologist for 30 years. I got 2 Interferon+ Riba treatment from 2007 , relapsed twice. Started Abbvie combo in August
veronika


Member

Status: Offline
Posts: 8
Date:
Permalink  
 

Dear Matt,

 

Your advice just came in time. I was thinking wich supplement should i take.  The only alternative treatment what I tried it was the Sylibin phitosome ( sylimarine product).  It was told to have some scientific evidence. Several product was told to be useful for liver and `hep `C virus. Several times I ordered it and the end I did not dare to take it.  So I have lot of unnecessary product in my desk. I still tired by the afternoons so no danger to overload myself with good programs. I still work 20 hours in a week- it is highly enough. 

Thanks



__________________

Veronika

Infected with Hep C Genotype  1/b  may be 50 years ago from series of transfusion or working as a neonatologist for 30 years. I got 2 Interferon+ Riba treatment from 2007 , relapsed twice. Started Abbvie combo in August
Matt Chris


Guru

Status: Offline
Posts: 1781
Date:
Permalink  
 

Hey Veronika

Congrats on your making it to your last week, you are well on your way to many more good days. With your early 2 week UND status your odds are greater than most in acheiving SVR. 

Best advice IMO try not to burden yourself with extra social schedule and your body with extra supplements. (My mistake)  Let your body settle in with its new dynamic and take over its normal functions.

Hoping the best for you.

matt



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
hrsetrdr


Guru

Status: Offline
Posts: 940
Date:
Permalink  
 

Veronika, Glad to hear you've completed the treatment, now hoping for your recovery and SVR.

__________________

"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
suziq


Senior Member

Status: Offline
Posts: 327
Date:
Permalink  
 

Hi Veronika,

Congratulations!!!! Now you get to face the major side effect of the new treatments--Waiting for final results.  Definitely causes anxiety!!!

I am in week 9 of Merck trial. Was UND at week 4--don't have week 8 results yet. The previous Merck trial showed great results at the Liver conference.  The new trial I am on tests cirrhotics, null responders and those with HIV. 

My coordinator, who works with several drug companies at the study center, said with the new meds that once someone is UND the chances are very high that they will be SVR.  Hope she is right for both of us.

SuziQ  



__________________

Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR
Cinnamon Girl


Guru

Status: Offline
Posts: 5629
Date:
Permalink  
 

Well done, veronika, you must be so happy to have finished your 12 weeks now!  I hope you start feeling better from the side effects very soon, and all the best of luck with your results!  You`ve responded very well to this Abbvie combo right from the start, so let`s hope the virus is gone for good this time around!!  smile  Keep in touch!



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
Zlikster


Guru

Status: Offline
Posts: 791
Date:
Permalink  
 

Congrats! good results too! :) hope you recover soon...



__________________

GT 3 dg. 08-2012 / FibroScan: 5 kPa F1 / FibroTest: F0-1 A1 / SoC TX: PegInt 120mcg+Riba 1000mg UND from w8 relapse EOT+4w
01-2016 Sof+Dac+Riba UND from w8, SVR24!
JIme


Guru

Status: Offline
Posts: 733
Date:
Permalink  
 

Congrats! It is a great feeling to be done.

__________________

jim

GT1a, St2 Lv2 last biopsy 2002, VL  11.4m,  start triple tx 9/30/11

VL 470 @4wks.....VL 22,000 @8wks  stopped tx

Round 2-  Started 3/16/12   PSI-7977, BMS-790052, Riba Undetectable day 14

Did 24 weeks Still UND 12 weeks post tx, SVR24!!!!!!! 2/14/13

 

 

 

 

 
mallani


Guru

Status: Offline
Posts: 3398
Date:
Permalink  
 

Hi veronika,

Congrats on getting to the end. With your previous results I don't think you have much to worry about. Hope recovery is easy. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
veronika


Member

Status: Offline
Posts: 8
Date:
Permalink  
 

Hi everybody,

 

I finished yesterday the 12 weeks treatment of Abbvie Malachit .  Now the countdown for SRV starting. As far as I checked my chance is 90% to forget the Hep C. Much better than win the lottery. 

Early this week from Nov 1-5 was held on the AASLD annual congress in Washington. Most of the abstract focused on new treatment option of Hep C. Quite promising data . If you have time check it. 

Veronika

 



__________________

Veronika

Infected with Hep C Genotype  1/b  may be 50 years ago from series of transfusion or working as a neonatologist for 30 years. I got 2 Interferon+ Riba treatment from 2007 , relapsed twice. Started Abbvie combo in August
veronika


Member

Status: Offline
Posts: 8
Date:
Permalink  
 

Dear Matt,

 

Thank you so much for your help.  It is really strange sometimes that I wake up with full of energy and by 2 pm. I feel like an empty battery. I work once a week late afternoon . But anyway I don't mind being down temporally if the drug will kill all the viruses. This one is my third series of treatment. The two previous failed to have permanent effect. The virus returned after as soon as the treatment was finished.  



__________________

Veronika

Infected with Hep C Genotype  1/b  may be 50 years ago from series of transfusion or working as a neonatologist for 30 years. I got 2 Interferon+ Riba treatment from 2007 , relapsed twice. Started Abbvie combo in August
Terry


Senior Member

Status: Offline
Posts: 123
Date:
Permalink  
 

Hi Veronika     There shows two arms to that study but assuming you are on the arm A you would be taking the ABT450r/267 , ABT333 and The Ribavirin. I am on the Abbvie turquoise II 24 week with the same drugs and not to worry the Ribavirin does wear you down and make you very tired at times. Try and get as much sleep as you can because that sure helps with the side effects. Take care Terry



__________________

Geno Type 1a stage 4 cirrhosis EOT 52 weeks SVR !!
Matt Chris


Guru

Status: Offline
Posts: 1781
Date:
Permalink  
 

Hello Veronika

Welcome to the forum you have found a good place.

Its good to hear your received UND at weeks 2 & 4 , that is a very good indicator for success.

As far being tired in the afternoon this is a common issue with the Abbvie combo drugs. I was on the same treatment and I generally had a tired feeling later in the day so don't worry about that. These Abbvie drugs are much easy on the body with a lot less side effects than standard care with Interferon.

Keep up the good results , all the best 

Matt



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
veronika


Member

Status: Offline
Posts: 8
Date:
Permalink  
 

I finish the  42. day of treatment today, being on Malachit II study ( 12 weeks of Abbvie combination for previously non-responders).  I got the  UND result at week 2 and 4. However I don't have significant anemia I feel very tired by afternoon. Is it common side effect or I am to sensitive and looking myselt too carefully?doh

 



__________________

Veronika

Infected with Hep C Genotype  1/b  may be 50 years ago from series of transfusion or working as a neonatologist for 30 years. I got 2 Interferon+ Riba treatment from 2007 , relapsed twice. Started Abbvie combo in August
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> Clinical Trial Participants -> Side effect
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.