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Post Info TOPIC: Good post-Rx labs for a cirrhotic


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RE: Good post-Rx labs for a cirrhotic
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Thanks for this post.  I was wondering about those levels and how they would shake out after tx.  You are an inspiration - what a long journey to normalcy!



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1a, 35+ years; liver cancer survivor 7-2012 surgery; triple therapy 12-2012 (Interferon, riba, victrelis) - end 48-week treatment Nov. 29, 2013 - post tx 24 weeks undetected - SVR.



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Malcolm,

I'm happy to see your good report, it's amazing that you're already 10 months post-tx, so glad that you're decades long fight is finally paying-off.

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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 



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So pleased it's all coming together so well for you Malcolm.  Caroline



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My husband had genotype 1a, 46yo, started triple therapy (peg/rib/vic) 23rd July 2012, VL prior to treatment 14 million, UNDET 12, 24 weeks, EOT 24th June 2013, EOT +1.5 weeks UNDET, EOT +12 weeks & EOT +27 weeks UNDET; SVR January 2014



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Good people deserve good things, what a nice Christmas present for you and your family Kind of look at you and Cinnamon Girl as great inspire rs just joking, when I grow up I just want to be like yous but right now  am battling a cold front and windchill but better than too much snow, Merry Christmas and more health and happiness for yous in the new year 

Bill and his girls



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Geno type 1  rib and peg September 2012 , 5 weeks tripple and viral down to < 15 und april Aug 25 finished stay at peg 3 rib and eprex + blood transfussion finished treatment Aug 25 2013



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Congrats to you! These results look great! (And so do you!!) Thanks for all you do on this board! Have a wonderful happy healthy holiday and new year! <3 xoxox

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 geno 1, started peg and riba 7/5/13, now 29th day is vicrellis ***tonib VL started 6 million, after 5 weeks 374,000, after 8 weeks 150,000....the big test for VL is 9/27 at 12 weeks  TAKEN OFF THERAPY JUST NOT WORKING FOR ME...12 WEEKS STILL HAVE 9000 VL



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life is good in your neck of the woods!!!! third time is a charm and you deserve it ! what dedication & determination you've mastered.

 

sandy,ucbgal

 



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Congratulations!!  Your Hgb sure looks nice.  Had to be really rough during Tx with your labs dropping so low.  My pre-TX labs were about the same as yours.  These new meds are really great--I am almost normal in all areas and still have 4 weeks to go.    

Enjoy your golf with your new found energy!!

SuziQ



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Geno 1A  Age 82 Treatment naive Cirrhotic Told I had liver disease in 1966. Diagnosed as Hep C 1999.Started Merck clinical trial with Riba on 9/9/2013 Week 1 and 2 <25  Weeks 4, 8, 12,16,18 UND.  EOT Jan 14,2014  EOT +12 UND   JULY 1 2014 EOT+24= SVR



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CONGRAGULATIONS!!



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Thanks Malcolm,



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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What excellent news, Malcolm, you must be delighted with these results!  How wonderful to see the difference now at 10 months post tx... all those weeks and months of struggling with difficult side effects were worth every moment! 

So pleased for you!  smile

 



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Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 



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Thanks guys.

Bob, GGT is Gamma Glutamyl Transpeptidase and is the most non-specific of the liver enzymes.  It is released from hepatocytes in many conditions.  It can be raised from smoking, age, arterial degeneration, caffeine, alcohol and virtually any drug consumption. If the ALP is raised as well, this is good evidence of liver disease.  It is used in the FibroTest (Fibrosure) for liver fibrosis, which is why I think this test is pretty useless. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm



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Looks good, platelets enzymes are very good. I never seen GGT on any of my blood tests.



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58 yo..Relapsed in 99 and again in 2004. Started triple therapy with Victrelis July 22,2012.  genotype 1a. week 8,12,16,24 VL Undetectable..E.O.T -- 6-22-2013,,,EOT + 24., UND. 

SVR !!!

 

~Bob~



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Hey Malcolm 

Considering all things, age, duration of infection, amount of previous treatments I say those numbers are good and will only get better with time and good circumstances.

matt



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"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 

Tig


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That looks excellent Malcolm! You've earned every one of those great numbers. I can only imagine how good that makes you and your family feel when you see those great improvements. As you say, "Cheers Mate!"



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Mallani,

Looks good buddy, looks like a heckuva ride there.!!! Am happy for ya brother!



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John


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Hi all,

Most of you have normal enzymes, but for me this has never been the case.  I've just had some blood work done, and my ALT is 'just' within the normal range, for the first time since I started keeping records, in 1988.      It's hard to predict how cirrhotics will respond to SVR, but I'm fairly happy so far. 

                           GGT    AST    ALT    Hb    Platelets

Dec. 2011             134     128    142    16.2    166k     (pre-Rx)

Dec. 2012             182     100     91      7.9     46k     ( after 10 months of triple Rx)

Dec. 2013              46      38      44     15.9    159k     ( 10 months post-Rx)

So, fellow cirrhotics, there appears to be hope. Cheers.



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm

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