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Post Info TOPIC: anyone relapsing on siolvaldi?
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RE: anyone relapsing on siolvaldi?
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I relapsed between week 4 and 12 EOT. I did the Sofosbuvir/ Ledipasvir FDC for 12 weeks. Also I was  UND at week 4 -12 while on the meds. 

Im taking the FDC again for 24 weeks  and went UND 4-8 weeks. Waiting on my 12 week blood work now. I guess we will see.



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ION-3 Trial- Sofosbuvir/Ledipasvir 12 weeks.. UND 4 weeks, relapsed 12 week EOT. 

3-4 on Ischank scale

 

Retreat ION-3 Trial- Sofosbuvir /Ledipasvir 24 weeks

GT-1 (1-31-14) Week 1 VL 62 -Week 4,8,12,16,20 UND EOT 7-18-14

Tig


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Hi John,

We've been discussing this recently and since this is such a new treatment protocol, the real time documentation on relapse rates simply doesn't exist yet. You have to resort to the reports provided by the study literature provided by the manufacturers.

Tig



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Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Hi .. I asked the same question and I think because this combo of meds is fairly new no one really knows yet... We might have to wait a few months to find out. 

 



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G1a prior tx 2005 with peg & RIBA -quit due to bad side effects. Follow up visit showed it was back. Current tx Olysio/sovaldi 673,000 vl on 3/21/14. May 1st undetected vl. EOT 12 weeks undetected!


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everyone seems to be achieving undetectable levels but is anyone relapsing?



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 

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