Hep C Discussion Forum

I've found no documentation that would indicate the likelihood of weight gain or weight loss as a result of these medications. I do know that the treatment I was on, was responsible for my weight loss over the last year. I have been experiencing some considerable discomfort following the end of treatment last December and as all of us should do following EOT, we need to continue to see our primary care doctors. The first few months of treatment I noticed a steady drop in weight and by the EOT, I had lost over 50 pounds. I know it wasn't because I wasn't eating, because I ate more while I was on treatment than I ever did before! I was on the Victrelis protocol and had to eat at least three times per day with the medication. But I still lost weight and it was a concern of my hepa doc throughout tx. 

As I mentioned, I've been experiencing some increased pain in my hips and large joints since EOT. I saw an orthopaedic specialist this week, along with my hepatologist and PCP, trying to determine what's going on. The XRays are showing mild evidence of arthritis, and some signs of bone spur growth that wasn't there a year ago. The physical limitation in my right hip is profound and the hepatologist and orthopod both agree that it's likely evidence of an interferon induced immune response. But they both admit that there isn't a lot of information out there on it when dealing with HCV patients. It's disappointing for me, because it's very uncomfortable. There's little they can do outside of monitor it and have prescribed Naproxen for the inflammation. The weight loss was mentioned and I've actually continued to lose weight, in spite of a normal diet and increased activity since EOT. I can only attribute it to treatment and the death of the virus. What other reason for the significant loss of weight is there? I know it wasn't a weight loss program I would recommend provided there is an easier way, lol! I'm hoping that it isn't a trend that continues and the weight loss levels out and stays stable. Currently I'm kind of enjoying being able to eat what I want without the punishment on the day I have to hit the scales!

Tig

It may just be your body is functioning better and absorbing more nutrients from what you are eating, I put on weight about 10lbs since starting tx and finishing tx from where my weight leveled off after losing so much from malnutrition of the ESLD , I have a better appetite so naturally you eat, then if your digestive system is working better due to better liver function I would think it would be somewhat natural to gain some weight.

just my 2 ¢

Duane