Hep C Discussion Forum

Members Login
Username 
 
Password 
    Remember Me  
Chatbox
Please log in to join the chat!
Hep C Discussion Forum -> On Treatment -> First VL results since SOT - thought I'd be happier....
Post Info TOPIC: First VL results since SOT - thought I'd be happier....
Penelope PePod


Senior Member

Status: Offline
Posts: 199
Date:
RE: First VL results since SOT - thought I'd be happier....
Permalink  
 

Thanks, RC.  Yes, those results were 4 weeks into TX.  I get week 8 results day after tomorrow.  I'm sure all will be well, and I'll be able to let out a huge sigh of relief.  I'll for sure post up when I get back from the doc.  Penny



__________________

65;  Dx 1997 1a; VL 1.1m; TX naïve; SOT 7/20/15; 12 wks viek/riba 1200mg

09/14/15 draw: Undetected 8 wks into tx

10/12/15 draw: Undetected at EOT

01/05/16 draw: Undetected at E0T+12
robertsamx


Guru

Status: Offline
Posts: 915
Date:
Permalink  
 

Your numbers all look good.  Your ast & alt are great !!   I know its tuff geting the news your not UND at 4 weeks, but that is still early in your treatment. If the news was at 8 weeks into treatment you might have cause for concern, but  if I understand your  post  correctly  these results are at 4 weeks??   Your on a good protocol. The riba is a little insurance for 1-a . Think of the riba as a security fence to keep out the virus, at least your fence is still up.That along with the Viekira Pak should do the job. In studys- viekira Pak  cured 95 % of type 1a and 1b.  There were 2,300 people enroled in these studys across 25 countrys. You will beat this. RC



__________________

 M-68, 3 Treatments)( SOF-RIBA 2014)(SOF-RIBA-PEG 2016)(HCC 2016) (LIVER TRANSPLANT 8-2017)(VOSEVI-RIBA 2017)   SVR-12. 3-13-18   
Penelope PePod


Senior Member

Status: Offline
Posts: 199
Date:
Permalink  
 

Thanks Jack and Matt - Definitely taking it easy and trying not to worry.  The end is in sight.

Jack - so sorry to hear about the anxiety and nausea.  I haven't had that.  Of course I take at least one Pepcid Complete every night before bed (doc said OK), and there were those few weeks of crying all the time (happy, sad, bored, hungry, whatever).  So maybe I have had some anxiety and nausea.... 

Be well.



__________________

65;  Dx 1997 1a; VL 1.1m; TX naïve; SOT 7/20/15; 12 wks viek/riba 1200mg

09/14/15 draw: Undetected 8 wks into tx

10/12/15 draw: Undetected at EOT

01/05/16 draw: Undetected at E0T+12
Matt Chris


Guru

Status: Offline
Posts: 1782
Date:
Permalink  
 

Hey Penny 

Hang in there, its almost certain that you are undetected by now, Stay well rested and don't push yourself to hard. All will be well in the end.

matt 



__________________

"And in the end, the love you take is equal to the love you make"

61 year old Geno type A1, F4 Cirrhotic, started 24 weeks on Harvoni 12-17-14 ,EOT-5 week = UND, 8-31-15 =UND , SVR-24 Baby YES! 
drummerman


Senior Member

Status: Offline
Posts: 100
Date:
Permalink  
 

Penelope PePod wrote:

Hey DM,

Just plugging along.  Had blood drawn last Monday for 8 week VL, but won't see results until my appointment next Friday.  I just hate this wait, and am very anxious that I'll still be >15 and detected. (I was at 34 at 4 weeks.)  Guess Mr. Riba is just having a bit of fun messing with my head. 

Other than that, I feel pretty good except for the fatigue, even after the riba was cut in half.   But I've got 3 weeks to go and I can do this!

You should have about 2 weeks to go, right?  How are you feeling? 

Thanks for checking up on me. P.

 

I feel ok.  Still feel like jumping out of my skin and having to take xanax to deal with that.  There were a couple of days where I cut my riba down to four...I just couldn't take it and had a lot going on  had to deal with.  It actually helped.  But I don't advise anyone to make that decision on their own....but I sometimes I get quite independent.    Slight nausea everyday.  Running out of breath and panting has gone away (yay!).  Itching has gone away (yay).   Thanks for asking.

  This is my last week!  But I hear it takes 2 weeks to start feeling normal again... that just not right.  But I remember my last tx with interferon... it took at least 4 months to start feeling normal.  It really messed with my head.  So I'll take 2 weeks over 4 months.

keep us posted! 

dm

 

 

 

 



__________________

GT1Adiagnosed in 2007Interferon/riba2008non-responder7-25-2011 HCV RNA-10,783,000 7/6/15startedviekira/riba8/11/2015 - Week 5>15, 9/11/2015  "HCV not detected IU/mL. AST 16 ALT1110/16/16 - 2 weeks post EOT HCV NOT DETECTED AST18 ALT 14
Penelope PePod


Senior Member

Status: Offline
Posts: 199
Date:
Permalink  
 

Hey DM,

Just plugging along.  Had blood drawn last Monday for 8 week VL, but won't see results until my appointment next Friday.  I just hate this wait, and am very anxious that I'll still be >15 and detected. (I was at 34 at 4 weeks.)  Guess Mr. Riba is just having a bit of fun messing with my head. 

Other than that, I feel pretty good except for the fatigue, even after the riba was cut in half.   But I've got 3 weeks to go and I can do this!

You should have about 2 weeks to go, right?  How are you feeling? 

Thanks for checking up on me. P.

 



__________________

65;  Dx 1997 1a; VL 1.1m; TX naïve; SOT 7/20/15; 12 wks viek/riba 1200mg

09/14/15 draw: Undetected 8 wks into tx

10/12/15 draw: Undetected at EOT

01/05/16 draw: Undetected at E0T+12
drummerman


Senior Member

Status: Offline
Posts: 100
Date:
Permalink  
 

Penelope PePod wrote:

Hi everyone and thanks for the pep talk.  Guess I'll quit being a baby, lift my chin off my chest, and be happy.  I'm just so darn tired.  But I'm looking forward to that changing once I get a little more 'red' in my blood.  I don't know how fast the hemoglobin recovers, but I'm sure I'll feel more like myself once it does. 

Penny  

 Whatsup??

Haven't heard from  you in awhile.

 

dm



__________________

GT1Adiagnosed in 2007Interferon/riba2008non-responder7-25-2011 HCV RNA-10,783,000 7/6/15startedviekira/riba8/11/2015 - Week 5>15, 9/11/2015  "HCV not detected IU/mL. AST 16 ALT1110/16/16 - 2 weeks post EOT HCV NOT DETECTED AST18 ALT 14
Groupergetter


Guru

Status: Offline
Posts: 796
Date:
Permalink  
 

Hi Penny,, We know these meds can make you feel rough. Hang in there, things will get better in time. You're doing great, SVR is just around the bend. Be well :)

__________________

1b  Int/Riba relapse @ 48 weeks.  Stop tx Peg Int/Riba 12 weeks ill. Relapse S/O 6/23/14 :(   Started Harvoni 11/12/14  EOT 4/28/15.  EOT+4 UND :)  SVR! 8/4/15  :)     Thankful for every morning.
Scruffy


Guru

Status: Offline
Posts: 500
Date:
Permalink  
 

Hi Penny

Looking good there. Ast and Alt are great!!!!!! Don't worry about the vl of 34, next draw like Tig said will be undetect. Two years ago we would have been upset over a riba reduction but with the new meds its ok. Keep your chin up the med's are working.



__________________

Geno 1a null responder 2004 inter/riba   finished incivek,peg/riba 48 weeks May 17th 2014. undetect weeks 4-12-32.  EOT+7 undetect. EOT+24 SVR!!!!! EOT+!YEAR SVR!!!!
Penelope PePod


Senior Member

Status: Offline
Posts: 199
Date:
Permalink  
 

Hi everyone and thanks for the pep talk.  Guess I'll quit being a baby, lift my chin off my chest, and be happy.  I'm just so darn tired.  But I'm looking forward to that changing once I get a little more 'red' in my blood.  I don't know how fast the hemoglobin recovers, but I'm sure I'll feel more like myself once it does. 

Penny  



__________________

65;  Dx 1997 1a; VL 1.1m; TX naïve; SOT 7/20/15; 12 wks viek/riba 1200mg

09/14/15 draw: Undetected 8 wks into tx

10/12/15 draw: Undetected at EOT

01/05/16 draw: Undetected at E0T+12
Cinnamon Girl


Guru

Status: Offline
Posts: 5629
Date:
Permalink  
 

Hi Penny, everything there looks fine, nothing to worry about!

Your vl has come right down and your liver enzymes, ALT and AST, are fantastic!  As Tig said, it`s standard procedure to lower your riba dose when your Hgb has dropped below 10 and it certainly won`t damage your chances of SVR. 

You`re on course and the treatment is doing its job well, you have every reason to be happy with the way things are going.  smile



__________________

Jill 

(71 yo, lives in UK)

Was Gen 3a, 

24wks Peg Ifn/Riba, Sep 2010 - Mch 2011

UND @ Wk.4, UND @ EOT, 

SVR Nov 2011 --> Still UND @ EOT + 4 yrs.

 

 
zavr


Veteran Member

Status: Offline
Posts: 99
Date:
Permalink  
 

You are right in track, Penelope!! although I remember feeling sad at the lack of ND as well, and no one could talk me out of it. :) in the hope that it will work for you, I really believe the medication has done incredible work. Look at the alt and ast! your liver is happy right now to feel a million times better! :)

Have you noticed a little more energy, perhaps?

 



__________________

Gen 1b, 33yo. Started 12wk Viekira Pak on 2/28/2015. 

Baseline: VL=517K, AST=34, ALT=56. 

Wk4: VL=<15, AST=16, ALT=14.

Wk8: VL=UND, AST=17, ALT=14.

Wk12: VL=UND, Fibroscan: 3.4kPa, F0.

--->Viekira Pak financial and nurse support<---
drummerman


Senior Member

Status: Offline
Posts: 100
Date:
Permalink  
 

yep, 34 is good.
going from 1.1 million to 34! Yeah, I would say you are right on track.

Lucky you got to reduce riba! I hate it.

dm

__________________

GT1Adiagnosed in 2007Interferon/riba2008non-responder7-25-2011 HCV RNA-10,783,000 7/6/15startedviekira/riba8/11/2015 - Week 5>15, 9/11/2015  "HCV not detected IU/mL. AST 16 ALT1110/16/16 - 2 weeks post EOT HCV NOT DETECTED AST18 ALT 14
Tig


Admin

Status: Offline
Posts: 9284
Date:
Permalink  
 

Hi 3P,

Your viral load of 34 is still excellent. Many people aren't undetected at week 4, some aren't at week 8, but at 34 I'm going to bet money that you'll be UND on your next test. Don't worry about that, you're doing just fine. 

Reducing your Riba considering your drop in labs is standard procedure and is expected. You're probably feeling a lot of fatigue with a hemoglobin <10. Everything is indicative of treatment with Ribavirin and is known as hemolytic anemia. It really does a whammy on your blood cells and causes the reductions you see in your lab reports. This is also an excellent sign that the medication is doing exactly what it's supposed to be doing. Reducing the Riba should stabilize them or bring them back up some and your doctor will follow them closely to be sure you continue on as planned. The ALT/AST are great! They are exactly where you want them to be. You're looking good girl!!! Nothing to be disappointed with there :>



__________________

Tig

68yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

Hep C FAQ   Lab Ref. Ranges  HCV Resistance

Signature Line Set Up/Abbreviations   Payment Assistance

 
Penelope PePod


Senior Member

Status: Offline
Posts: 199
Date:
Permalink  
 

Saw the doctor today and got VL results from blood drawn 4 weeks into tx.  I updated my sig line with new results.  34 is good, right?  I saw 15 on lots of other folk's results, including my hubby, and I sort of thought that's where I be.  Am I being silly? 

Also, because my HCT, RBC and HGB have all dropped so much, the doc cut my riba dosage in half, from 1200mg daily to 600mg, and ordered weekly blood work.  He assured me the lower dosage should not jeopardize my ability to achieve SVR, but I wonder.  

Has anyone else had their riba lowered and still reached undetectable?   Is 34 OK? 

My next VL draw is in 2 1/2 weeks, plus 1 1/2 weeks to get results.  It's gonna be a long 4 weeks.

Penny

Hmm, can't seem to update sig line, so here's the info. 

         SOT plus 4 wks    Before TX

rbc           3.25          4.72

hgb           9.7           14.3

hct           29.8          41.9

ast            17            28

alt             14            28

VL             34           1.1m

-- Edited by Penelope PePod on Saturday 29th of August 2015 01:40:34 AM



-- Edited by Penelope PePod on Saturday 29th of August 2015 01:54:41 AM

__________________

65;  Dx 1997 1a; VL 1.1m; TX naïve; SOT 7/20/15; 12 wks viek/riba 1200mg

09/14/15 draw: Undetected 8 wks into tx

10/12/15 draw: Undetected at EOT

01/05/16 draw: Undetected at E0T+12
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.
Hep C Discussion Forum -> On Treatment -> First VL results since SOT - thought I'd be happier....
Legal Disclaimer:

THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.