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Hep C Discussion Forum -> Liver Transplant -> Labs
Post Info TOPIC: Labs
sailing shoes


Veteran Member

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Date:
Labs
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Ahhh Boxers ... what a mess, eh? I had a lingering cold right after the transplant. I can relate. Some thoughts:

Recovery isn't linear, there are lots of ups and downs along the way.

Recovery takes a lifetime, in that we have to be vigilant and watchful forever. That doesn't seem to end.

You're in the critical first few months, when your entire system is reacting to the shock and stress of the
invasion and is trying to accommodate and stabilize. You put it so well - there is a rear view mirror in your
future. You'll get there.

Actual rejection is rare. There are established procedures and protocols to keep the immune system in
check and keep your new liver onboard. My enzymes spiked once, then settled back on their own.

As Tig, et al, pointed out, you have a cold, a lingering cold, that stresses everything. You just have to wait
it out. And not pass it back and forth with your hubby. (doesn't he have tomatoes to look after?)

It takes a long time, Boxers. That's from my short-term perspective of 20 months post. I'm beginning to agree with Bob Dylan's line, "you can always come back, but you can't come back all the way." Something like that. By the time you get back, you're that much older. The 21 year old indestructible girl is definately in your rear view mirror.

Good luck with labs. You mentioned kidneys and enzymes were heading back to normal. I always try to drink an extra ton of water the day before labs. I just wanna get a good score, a passing grade. And besides, it's always good to flush the kidneys.

Hell, you already know all this.

Side note, my granddaughter just stopped by on her way back to college. She had her brand new 10 week old puppy with her. Her un-vaccinated, un-wormed, un-trained 10 week old puppy from a back-yard breeder. I truly love dogs, and puppies are the best, and I love my granddaughter to pieces. But I irrationally freaked out at the thought of being around a little germ bag of an un-wormed pup. There was a worm incident and I couldn't relax for the three days till they left. I'm still a bit shaken by the realization of my vulnerability.

But I'm still here, on the right side of the dirt, as my little brother used to say.



__________________

70 YO M, Dx 1999, 1a, cirrhosis; Pegasys/Riba Neupogen Aranesp in 2001, partial responder; PegIntron Riba 2002, partial; Phase 2 Clinical Trial Pegasys/Valopocitabine 2004, relapse at EOT; Sovaldi/Olysio 2014, SVR; HCC 2015, TACE 2016, Transplant 2016
Canuck


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Too much going on Boxers, you are right, it's still too fresh, too new, you are a brand new newbie NOT to be be reactng with a bit of worry to tweeks, changes and how you are feeling, who would NOT, I would have never been as calm, and brave and forward looking and thinking as I see you and RC and SS being! You have been through so much and still have all this work to get through, but look at you, you are getting there, home and recovering and doing it come hell and high water (and troughs)!

I think Tig is right, just about drugs affecting ALT, and I read that lots of transplant people have some of their LFT's that just run a little high, sometimes always ever after, and the post-transplant before and after change/gap in your ALT is NOT canyonous.

You have a compromized immune system (not your fault - theirs, as it is part and parcel effect of the meds/treatment you are on), you have been through horrific prolonged duress/stress, major body and mind warp surgery, your body is VERY busy with drugs and healing, and you are fighting some coldish thing, and so many new things and situs have been thrown at you all at once continuously for weeks and months now, no wonder you are at a distinct disadvantage to be feeling a little concerned from time to time.

Keep on, with what you are supposed to be doing, moving, healing, eating, drinking lots, sleeping, resting, keeping occupied. 

Nice the tac is back in the wanted correct zone again, and that the GFR followed suit that quickly. You are not mission impossible, you and RC and SS are living proof that anything is possible - mission possible! Just requires tweeking. Holy cow, I am still amazed at the thought of what a miracle this really is. 

We are all going to chip in a get you a REALLY big rear-view mirror. wink C.

Related image



__________________

HCV/HBV 1973. HBV resolved. HCV undiagnosed to 2015. 64 y.o. F. Canada.

GT3a, Fibroscan F3/12 kPa - F4/12.6 kPa, VL log 7.01 (10,182,417), steatosis, high iron load.

SOF/VEL with/without GS-9857 trial - NCT02639338.

SOT March 10 - EOT May 5, 2016 - SOF/VEL/VOX 8 week trial.

 

(SEE UPDATES IN BIO)
Hoodietree


Senior Member

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Youre very gracious boxers. I sincerely hope your liver tests start showing signs of improvement pronto. are you taking any supplements or doing any nutrition programs? that can of course be very tricky and filled with conflicting info. Im praying for you and hoping for the very best. 



__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 
boxers


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Hoodietree, yes I was treated successfully with Harvoni in 2015 but I was already decompensated....esophageal varices with bandings, HE, Tips procedure, umbilical hernia, paracentesis, going down hill but unbelievably I felt pretty good. My liver had too much damage to come back. Wish Harvoni had been around 10 years ago. I am so happy for the people that get this option...a true blessing!



__________________

65 yo female

dx. 1996

TX with interferon/riba 2001..failed

Uncompromised 2015

TX with Harvoni  2015..virus undet.

Meld 14 7/2017  TIPS 1/2017

 

TP 5/12/18 
boxers


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Iris, I did the Harvoni for 12 weeks and was SVR before transplant. They do test donor liver when they receive it but I doubt they have the results that quick. Good question.

 



__________________

65 yo female

dx. 1996

TX with interferon/riba 2001..failed

Uncompromised 2015

TX with Harvoni  2015..virus undet.

Meld 14 7/2017  TIPS 1/2017

 

TP 5/12/18 
boxers


Veteran Member

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Posts: 75
Date:
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Observer, yes they have drawn labs with the cold but they don't seem concerned. I am the one that usually poo poo's symptoms...don't like it when they do.

 



__________________

65 yo female

dx. 1996

TX with interferon/riba 2001..failed

Uncompromised 2015

TX with Harvoni  2015..virus undet.

Meld 14 7/2017  TIPS 1/2017

 

TP 5/12/18 
boxers


Veteran Member

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Posts: 75
Date:
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I do have allergies but that has been going on for 25 years. My concern with the labs is that they don't take a dip, it is just progressively going up. I wish I knew what a concerning or critical "up" is in the post transplant world. I am going to have new labs Wed. and Doc. on Friday. Fingers crossed.



__________________

65 yo female

dx. 1996

TX with interferon/riba 2001..failed

Uncompromised 2015

TX with Harvoni  2015..virus undet.

Meld 14 7/2017  TIPS 1/2017

 

TP 5/12/18 
Tig


Admin

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Posts: 9270
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Hi Boxers,

That cold has been plaguing you and your hubby for too long! I hate having to deal with those hangers on type colds. Ugh... Is there a chance allergies could be getting you as well? This is an awful time for us here in Florida. Everything is blooming and the palm trees are the worst. I’ve never seen anything dump pollen like they do. Clouds of yellow crap everywhere. Then there’s the pine trees...

What is your doctor saying about the LFT elevations? Until they get things stabilized and your medications figured out, I imagine those enzymes are going to fluctuate. Medications by themselves can cause wild fluctuations in your enzymes. I hope once they can get your levels figured out, the labs will begin normalizing.

It would be interesting to see the photos of your old liver and the tumors. I’ve seen a few of RC’s MRI’s and he was a real tumor factory. They would ablate one and two more would pop up. You both received your transplants just in time! 

How are the tomatoes? How about that big thing in the manure pile? Be careful of that thing, it could reach out and grab you, lol! 



__________________

Tig

67yo GT1A - 5 Mil - A2/F3 - (1996) Intron A - Non Responder, (2013) Peg/Riba/Vic SOT:05/23/13 EOT:12/04/13 SVR 9+ years!

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Observer


Guru

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Well darn those pesky LFT s .  What does your team or nurse or whoever is guiding you through this have to say about the slightly elevated numbers? I was wondering if your blood was drawn while you had that nasty cold and if that cold affect them?

So glad youre keeping us in the loop boxers

 



__________________

61 y/o, Infected via transfusion Oct'83, GT-1a, F-4 cirrhotic,
tx Holkira pak/moderiba 12 weeks

4 years.... successful dragon slayer 
Iris Dragonfly


Guru

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Boxers, I apologize not being up on your journey, i was wondering if you did the Harvoni before or after your liver transplant? Is it possible you may have to do the treatment again if the new liver had become compromised somehow? I feel for you, i cannot say Don't be afraid,  I would be right there with you, stay strong, yell when no one is looking if you need to.

Wishing you the very best.

Iris



__________________

in the silence of the woods, you will not be alone- Chief Seattle

60 years on planet, Female, diagnosed 1978 as non-a non-b, VL 8mill+, Fibro f-1f-2, Genotype 1a, treatment naïve....UNTIL 7-01-18  !!!! started Harvoni 12 weeks. :)

4 weeks=UND, 8 weeks=UND, 12 weeks=UND (EOT= 09-23-2018)
Hoodietree


Senior Member

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Boxers do I understand correctly that you were successfully treated in 2015 and have been trying to get your health back ever since? Im too new here to offer any insights but Im sure the veterans can help you. They are an invaluable resource. Hang in there my friend I pray all good things for you. 



__________________

F, 51, GT3, HCV since 1989, no alcohol since 1999, Fibrosis score F0-1 (.36), VL 216,000, ALT 23, AST 26, Epclusa SOT 7/26/18 EOT 10/18/18. Thank you God. 
boxers


Veteran Member

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Well having trouble controlling my Tac. levels  (12.4) and kidney function going down (GFR 51). They assured me today it was not that serious, just the game you play adjusting meds...tsk tsk (to quote Sailing Shoes). Did request my pathology report and pictures, they have no pics but they printed the report and forgot to give it to me. My nurse coordinator told me to contact the pathology dept. to see if they would give me photos, and if I get them to Interestingly, I had three more tumors in my liver so I guess it was time to go....lucky me! Still fighting this crappy cold, 2  1/2 weeks and now my husband has it. Attaching this graph of Tac. levels to give you an idea of how wild it is.  I this a week ago (7/18)....must not have sent...oops!

Well today is 7/27 and now my liver labs are off, ugh! July labs: ALT  39-54-now 95  normal (14-54)   AST  24-37 now 52  normal (10-45). I will get a repeat lab next Wednesday. On the bright side my Tac. level is now 7 and kidney function normal. They increased my myfortic to 4 (180mg tabs twice a day) for the increased liver enzymes. I wish I was RC and the rest of you that are looking at this in the rear view mirror. Still to fresh not to be a little scared. Anyone else have trouble with your enzymes? RC are you getting your energy back? this roll on my waist and stomach makes me feel like the Michelin man...lol!



__________________

65 yo female

dx. 1996

TX with interferon/riba 2001..failed

Uncompromised 2015

TX with Harvoni  2015..virus undet.

Meld 14 7/2017  TIPS 1/2017

 

TP 5/12/18 
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