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Hep C Discussion Forum -> On Treatment -> should i extend treatment?
Post Info TOPIC: should i extend treatment?
LanaiSurferGirl


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RE: should i extend treatment?
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Hey, I did an additional 12 weeks of treatment but I had to stop ribavirin for 2 weeks and be on a reduced dose of it fo another 4 weeks due to severe anemia.  If your treatment has gone well so far and you have had no bumps in the road I would investigate all options available to you.  There is evidence to support the longer treatment helps if you have cirrhosis.

good luck,

Meghan



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geno 1a, mother & brother also hep c +...mom got a blood transfusion and passed it along.  Started tx with incivik 11/23/11 and brother started 2/8/2012.  Both of us und. at 4,8,12 and me at 24.  I am going 36 wks and brother is going 48 weeks.
Bills


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As for me The more I think about it the more  I am on the fence, I'm listing to my gut about this now   I have about another 8 weeks before I have to make that decision   I'll just see how things go next  8 weeks to decide I can go as long as I want after that or stop



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Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial  in Aug 2011 -July 2012 into Incivek relapsed  Feb 2013 Had 72 weeks on interferon & Riba.

hrsetrdr


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cmerduran wrote:

you know, standart treatment period is 24weeks at triple therapy if you succeed rapid response..
i got UND at 23rd day, my last test was at 12th week and it was UND also..
now i am at week 17...
but at last meeting my doctor told me that he wanted to extend tx 8 more weeks to guarantee SVR because i tolorate tx very well (total 32 weeks) 
should i extend tx? i cant decide.. 

 I had to quit tx at week 16, due to Pegasys causing autoimmune damage to right eye's optic nerve.   I testd UND five weeks afterward; I won't get another VL test until March.

I would have preferred to continue tx to maximize my odds to achieve SVR...just my 2 cents worth.



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"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
cmerduran


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yesterday i had a meeting with Prof.Dr.Ulus Salih Akarca,, who is specialist about hepc... he worked also during lab studies of protease inhibitors.

i asked same question to him.. according to doctor if a patient succeed RVR (4 and 12weeks UND) with triple therapy then extending treatment has no positive effects on SVR.. and he adviced me to stop therapy..

i am going to wait until the end of treatment and then decide what to do.






__________________
Murat
28.07.12: HCV-RNA +, VL:7.1m, 1b
02.08.12: incivo-riba-pegasys started
24.07.13: HCV-RNA: WEEK 3, 12, 24, 36, 50 UND(SVR!!)
*all men have fears but the brave, put down their fears and go forward... sometimes to death, but always to victory.
Bills


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That extra 12 weeks seems like it will be forever and such a shock   I was told after breaking though@ 48 weeks   I might get away with another 24 weeks  triple  I cried when I had to take shot 49  now I'm told 48 would be better and they want me to do 48 I'm so scared of breaking through again I'm accepting the sentence. It makes me sick just thinking what if this doesn't work either I've already got 64 weeks in If I stop mid stream and break through  I will loose it  Funny thing there is no guarantee I hope I hold out and hope it works  



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Bills

Harvoni started 12-12-14 for 24 wks PrevTX Geno 1 stage 3 cirrhosis - non resp Int/ ribv. Started Trial  in Aug 2011 -July 2012 into Incivek relapsed  Feb 2013 Had 72 weeks on interferon & Riba.

news


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I did an additional twelve weeks, for a total of 36, and I am glad I did. If the doctor wants you to do it, I think you should.



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Geno 1A  Started Pegasys/Ribavirin/Incivek Nov. 20, 2011 .  Completed July 28, 2012 (36 weeks). For a treatment history, see:  https://jshare.johnshopkins.edu/xythoswfs/webview/_xy-9921874_1

SVR on January 14, 2013!!
kiwi


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cmerduran wrote:

you know, standart treatment period is 24weeks at triple therapy if you succeed rapid response..

i got UND at 23rd day, my last test was at 12th week and it was UND also..

now i am at week 17...

but at last meeting my doctor told me that he wanted to extend tx 8 more weeks to guarantee SVR because i tolorate tx very well (total 32 weeks) 

should i extend tx? i cant decide.. 

 i would listen to my doctor. good luck



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kiwi. genotype 1. started pegasus and riba on 10 nov. VL 17.6 million. (4 weeks VL 1368)  week 15 UNDETECTED... :)
marktrux


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When my Dr. and I met at 24 weeks we discussed ending treatment then and the advantages of extending treatment. He explained that all the current SVR numbers are based on a full treatment coarse of 48 weeks, not on a shortend coarse. He left it up to me to decide, and i chose the full 48 week coarse. Considering the fact that the worst 12 weeks(incivek) were long since over and the fact that Interferon and Ribaviran have been used for many years with minnimal long term adverse side effects. It may just be me but i've had treatment fail three times before and i dont want to have to go through this again.



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KCCO

 

 
12Step Guy


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Cmerduran , I would consider what the longterm possiblities are. If you relapse how likely is it that you're able to particapate in a trial of one of the new combo's, if it is likley I might stop at 24 weeks.  But on the other hand it is unlikely that you can access the new drugs, I'd extend and get the biggest bang you can out of this Rx. 

Capt. Butt Rash



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Genotype 1a, IL 28 = CT  Interferon and riba 48 wks in 99, Daily Peg and Riba 18 months in 2007, Started Incivek, Peg, Riba 6/21/12. 4th stage cirrhosis. Last Dart will be May 23 2013.
mallani


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Hi Murat, this is up to you and your doctor. If it was me, with your excellent response, I would follow the protocols and finish at 24 weeks. These drugs may have long term side effects, and the sooner you can get off them the better. What is your doctor's evidence that another 8 weeks would alter your SVR chances? Good luck with whatever you decide. Cheers



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Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
JoAnneh


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Hi! I am doing 48 weeks!
You have come this far, why not go all the way!
If it comes back, you will be able to say to
Yourself you did everything you could!
I say follow doctors order.
JoAnne

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JoAnne

Genotype 1a, Triple therapy w/Invicek started May 19, 2012

DET 4 wk. UND 2,6,12,24 48 treatment. Achieved SVR 2013!
cmerduran


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you know, standart treatment period is 24weeks at triple therapy if you succeed rapid response..

i got UND at 23rd day, my last test was at 12th week and it was UND also..

now i am at week 17...

but at last meeting my doctor told me that he wanted to extend tx 8 more weeks to guarantee SVR because i tolorate tx very well (total 32 weeks) 

should i extend tx? i cant decide.. 



__________________
Murat
28.07.12: HCV-RNA +, VL:7.1m, 1b
02.08.12: incivo-riba-pegasys started
24.07.13: HCV-RNA: WEEK 3, 12, 24, 36, 50 UND(SVR!!)
*all men have fears but the brave, put down their fears and go forward... sometimes to death, but always to victory.
gatekeep


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Sounds like you had a great TX. I would go for the longer Tx just so you know you have done it the way it was prescribed.

-- Edited by gatekeep on Sunday 18th of November 2012 03:20:43 PM

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25 yrs HepC. type 1a geno. 6mill viral load,3.5 out of a 4 liver biop.started Sept.19, 2012,Tx.Rib.,Incivek, Peg,4wk. Vl 61,undetected @12 wks,undetec.Wk 24
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