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Hep C Discussion Forum -> On Treatment -> fatty liver
Post Info TOPIC: fatty liver
Huey


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RE: fatty liver
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mallani wrote:

Huey,

MRI is much more sensitive than CT. With CT I've tried all the attenuation protocols for liver-spleen differentiation, and have been sadly mistaken when a biopsy or MR is done.

Tim: Fatty liver (NASH or NAFLD) is common, and by itself can lead to cirrhosis and/or HCC. Your GI is generous- a BMI of <28 is better. Cheers.

 Thanks I will keep that in mind, Ct is what the nurse wonted, so it is what she got.



__________________

  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
Isiscat2011


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Huey wrote:

 I hope your right about those spin-echo sequences.  I wish to avoid a biopsy.  If this CT tells us enough, I will not do any biopsy.

I don't think you will need a biopsy, Huey.  They can tell a great deal by MRIs and CTs with contrast.  I wouldn't have another biopsy unless there was no reasonable alternative.



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
Isiscat2011


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I was recently diagnosed with type 2 diabetes but it is just on the cusp (my hgbac1 is 6.5 or 6.6).  At about the same time my last MRI showed the beginnings of fatty liver.  

My BMI only runs about 22 so my PCP said not to lose weight but to take Metformin for the diabetes.  

I decided not to take the Metformin because I think my glucose will correct itself when I SVR (in the very near future I hope).  I have gone to a low-glycemic diet, though.  My non fasting glucose only runs about 130.  Now I have to tell my PCP that I'm not complying with his instructions to take Metformin.  I hope this wasn't a bad decision on my part; I just don't want to get started on diabetes meds and Metformin can be bad for the liver.  

Does anyone else here use Metformin who has cirrhosis?  



__________________

Diagnosed in 2011, Incivek triple in 2011, tx discontinued, Genotype 1a, CT, VL 7mill, cirrhosis dx in 2012, age 67, waiting for new DAAs.
mallani


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Huey,

MRI is much more sensitive than CT. With CT I've tried all the attenuation protocols for liver-spleen differentiation, and have been sadly mistaken when a biopsy or MR is done.

Tim: Fatty liver (NASH or NAFLD) is common, and by itself can lead to cirrhosis and/or HCC. Your GI is generous- a BMI of <28 is better. Cheers.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
hrsetrdr


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Hi John,

My gastroenterologist warned me that I was at increased risk for HCC if my BMI was over 30. I stopped eating(not really), along with stopping drinking, smoking, using salt and suger,,,and stopping every other thing that I enjoyed...that was bad for me. Seriously, I did commit to eating healthier and exercising, which got my BMI down much closer to 'normal'.

__________________

"hrsetrdr"=Tim

Treatment halted on Aug.8,2012 due to vision problem.  6 month post tx labs

Aug.2013 SVR

Be strong when you are weak, brave when you are scared, and humble when you are victorious.
- Unknown

 

 
longld


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Was teasing my Liver doctor about her retiring after HepC is eradicated with all of the new treatments - she stated that fatty liver promises to be a bigger issue than HCV ever was.



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62 Yrs Old, CHC Geno 3, Cirrhosis, Kidney Transplant (13 yrs), On Sovaldi/Riba Treatment (24 week) since Feb 01,2014

Viral Load 7M on 1/8/2014,  UND at EOT 7/18/2014
Huey


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mallani wrote:

Hi John,

Using the latest spin-echo sequences, MRI is almost as good as biopsy at detecting fatty liver. Accumulation of fat in hepatocytes is common, but we should try to reduce it, as it causes hepatocyte damage. It is common in overweight patients and particularly in diabetics. Try to lose some weight. Fatty liver accelerates fibrosis progression and gives an increased risk of HCC.

 I hope your right about those spin-echo sequences.  I wish to avoid a biopsy.  If this CT tells us enough, I will not do any biopsy.



__________________

  HCV Genotype 3a , now Psot-Tx was on S/riba. First VL was 5.8 mil on 7-5-13 then "und" at 3.8 weeks. 06/13/14 still und. off meds 3 days back on 7/29 Last pill 08/10/14 SVR+4

 
mallani


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Posts: 3398
Date:
Permalink  
 

Hi John,

Using the latest spin-echo sequences, MRI is almost as good as biopsy at detecting fatty liver. Accumulation of fat in hepatocytes is common, but we should try to reduce it, as it causes hepatocyte damage. It is common in overweight patients and particularly in diabetics. Try to lose some weight. Fatty liver accelerates fibrosis progression and gives an increased risk of HCC.



__________________

Geno 1b, IL28B CT,  x3 prior relapser,  ex-cirrhotic, 75 yo, did 48 weeks with Victrelis/Peg./Riba.  VL 1.28m at start, UNDET. at 8 ,12 ,16 ,24 ,30  and 48 weeks.  EOT 15 Feb 2013 , UNDET. at EOT + 28 weeks. SVR!  Still Undet. at EOT +5 years

Malcolm
JLynch30


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My latest MRI says fatty liver - I am a little overweight - how dangerous is this for our liver?



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John   non-responder  

Undetected at week 2 on solvaldi/rib/interferon:  stayed through week 12 but virus came back as soon as I stopped.  on   Harvoni and ribravirin 24 weeks undetected after two. 8/2/15  12 week EOT  UNDETECTED!  SVR

1991-2015 RIP

 
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