I started my treatment of sovaldi and ribavirin last Saturday and had no side effects until the past 24 hours. My skin has been crawling since yesterday and feels really prickly as if someone rolled me in fiberglass dust or something. Is this a known side effect of ribavirin? My dentist gave me a prescr...
Hi folks, I started this trial about 9 weeks ago and end treatment at the end of this month. Is anyone else in this trial? Its very intensive in terms of clinic visits but seems to be having good results. Karen
Hi Everybody..... It has been a while since my last confession................... Anyway, Been left fallow now for over 12 months after TX failure (12 months Inter/Riba Type 3c) No further TX allowed in this area. I seem to have developed rapid Arthritis Symptoms, pain, restricted movement in elb...
I had my treatment last year and it was succesfull. My friend had also treatment, he was going to be in medication some months, so it was easy genotype. He had something wrong with his hearth and blood. He died an hour ago because of side effects about his treatment. I am just cryin for him. Why him?
I am 2 weeks into the lead in phase of 4 weeks for Victrelis. The plan was 4 weeks lead in then 44 weeks of peg/riba/victrelis.. Went to doc today and nurse told me doc got a report from VA saying Incivic has higher rates of response in VA treatment (for cirrhotic)and they are going to continue the 4 weeks l...
New member and my first post. Gilead - LoneStar-3 Open Label Study of Sofosbuvir/Ledipasvir Combination with Ribavirin or GS-9669 250 mg or GS-9669 500 mg in Treatment Naïve or Treatment-Experienced Cirrhotic Subjects with Genotype 1 HCV. (Not posted on clinical trials.)Just started this...
Idenix Pharmaceuticals Announces Initiation of Phase II All-Oral Combination Study of Samatasvir (IDX719) and Simeprevir (TMC435) for the Treatment of Hepatitis C Virus (HCV) InfectionIdenix Pharmaceuticals, Inc...today announced the initiation of the phase II HELIX-1 clinical trial eva...
Hi all, My fatigue is increasing to the point that some days I can barely do anything. I'm hoping to do the newer dual treatments when they are approved in 2014 but until then, I'd like to continue with my life. What do you all do to help with fatigue symptoms? Laying on the bed all day doesn't seem to be a...
Hi everybody, well the labs are back and it's official - UND! my blood work is splended - WBC 4.3; RBC 4.18; HGB 14.0; ALT 26; AST 22; platelets 234 mcv is still high at 99. breathing easier and oh so very grateful for the blessings in my life.
I am about 9 days into Incivic and am experiencing the common butt burn, OUCH. Have found that using gummi fiber helps considerably but read on I-net that it slows absorbtion with some drugs. It lists several drugs but cant seem to find any thing specific to Teleprevir. So I am wondering if any one ha...
Just saw my Dr today & he was all excited about the new "game changer" - (ya right I thought). He told me about the FDA approving Sovaldi (sofosbuvir) with Ribavirin & he could get me on it today if I wanted. He was way more excited about it than I was since I'd be the one who'd be feeling l...
Hi all,Most of you have normal enzymes, but for me this has never been the case. I've just had some blood work done, and my ALT is 'just' within the normal range, for the first time since I started keeping records, in 1988. It's hard to predict how cirrhotics will respond to SVR, but I'm fairly happ...
INGELHEIM, 16 December, 2013 - Data show that Boehringer Ingelheim`s second-generation protease inhibitor faldaprevir, when used in combination with pegylated interferon and ribavirin, was effective even with the presence of naturally-occurring mutant variants of the hepatitis C virus (H...
I have not been posting much. Really have not felt well during treatment. Then 5 days after my last pill, 10/31/2013 another tragedy. My girl friends 22 year old passed on, unexpectedly. So I really don't no how much is from tx or how much discomfort is related to Travis's death. I just know now I have PH...
Over the last day and a half I've noticed the increasing discomfort in my right ear. Actually it's quite painful inside, outside and the eustachian tube is bubbling, popping and beginning to close I suspect. I had problems years ago with terrible external ear infections primarily but the occasiona...
Hi all, this is my first post. I was diagnosed in early 1993. I was young and resigned myself to the fate of an early death. I lived recklessly with drinking and drugs but after about 5 years passed, I realized I was healthy and had no symptoms. I got proactive and saw a doctor, the doc said I was undetecta...
Yesterday I had an appointment with my hepatologist. He check my viral load ( in 8 months up to 1.300.000,from 800.000 , do you know if this is significant? ) . Another lab test, normal.We commented, about future treatments with sofosbuvir ,when approved in Europe, and the possibilityof waiting ....
Just got the result today, and we both are really happy about it. Only 3 more months until he achieves SVR. Plus, he is not having any side effects post treatment and is back to his pretreatment self! ~ Carol
I started out on the dbl drug tx 48 weeks. After 4 weeks my VL went from 3m to 280k. They told me to take a break while they see if they could get me the third med. Judging by the amount of med left on the script looks like it was 6 weeks. With the third med I was undetectable at 4 weeks and again at 12 weeks <5. To...
tomorrow is my EOT and last 4 ribo pills!!!!! yippee. have consumed 100% of the inciveck and pegasys,but only 83% of the anemia causing ribo. my hemo is holding at 7.8 w/ 2 procrits/week !!!! am still und and will march onward to the coveted SVR. ast/alt/ggt are 33/40/40,while ferretin is still in 160...
Hello, I am on the Sapphire Trial and after 3 months discovered I was on the placebo and am now into my fourth week of the real meds. Strangely enough I felt pretty appalling throughout the placebo - general malaise, aching body etc. Guess it was the virus. I am also getting side effects from the real meds...
Sovaldi (sofosbuvir) - Full Prescribing Information, from Gilead Sciences.http://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf
Hey All I was reading some of the news in about Sovaldi and this topic about Gilead getting approval for GT-1's being able to either receive treatment for 24 weeks with Ribavirin only or 12 weeks with peg & Riba. Like the article reads, I don't remember any hard data that suggested that 24 weeks with...
I started the second therapy (Ribavirin+Interferon+Telaprevir) in Norway, but during the therapy moved back to Latvia, and have now two different recommendations from doctors regarding the therapy length. Norwegian doctor says that therapy can be finished after 24 weeks while the doctor in La...
I have 2 WK post EndTrial visit 2morrow. Tx SEs continue- stomach churning on laying down, all night, continues. Problem sleeping w stomach rumbling all night. BTW, anyone been hearing how the pre-SAPPHIRE, P2 (AVIATOR) are doing with SVR. Those trial folks s/b ~40 weeks.
>>>EOT<<< The day has arrived! Last night at 11PM I ate the last 4 capsules of Victrelis. That ends my 28 week course of Triple Treatment. At midnight I had a small personal celebration and turned off all of those damn alarms I had set on my smartphone as medication reminders. I look...
Hi all,Continuing my post-Rx saga, today I saw a Rheumatologist about my post-Rx aches and pains. It took 2.5 months to get an appointment and he looks after liver patients from most of the Hepatologists in Brisbane.After checking my Xrays, blood tests and physical examination he concluded I had r...
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