Gilead's exploration is ongoing re: RAVS and development of using of other possible alternate NS5B drugs like SOF and GS-9190 in combo therapies.Early trials on GS-9190, comparing classes of a "non-nucleoside inhibitor" (NNI) and "nucleoside inhibitors" (NI's) in newer DAA double and triple...
Hi all,Tig has a Sticky on Extrahepatic manifestations of HCV, but I'll add to this, using my personal experiences.Back in 2013, during my 48 weeks of treatment, I started getting some numbness in my feet. No big deal.This has slowly become worse and extends to just below my knees and has also started...
Dear Fellows, I was diagnosed HCV patient in 2007 and in 2008 i took successful treatment and PCR got negative. Since than all lab results are normal except ALT. It remains always between 55-70. Can anyone suggest why ALT is not showing normal range and what could be the reason of high level. My recent r...
Hi all,When the Molecular Pathologist rang me with my VL results last week, we had a chat about the VL testing.In March 2016, Australia gave access to Sovaldi, Harvoni and Daclatasvir to all HepC patients for a few dollars a course. My Lab is a private one, but does half of the VL testing for Queensland....
Liver Anatomy/SegmentsNever studied up on anatomy of the liver much, just vaguely knew there were left and right lobes, "roughly" where the gall bladder sat in relation to the liver, common bile duct connection, location of pancreas, etc., the most rudimentary familiarization of what is the CROW...
Thank you for the warm welcome. Well, basically to sum my life up briefly. Got married at 18 to a soldier (that was 21). He got "alerted" on our honeymoon (about two hours after getting hotel) and the next time I seen him was 14 months later. He got out of military in Sep 02. I was diagnosed with Hodgkin's ly...
France gets larger discount on Sovaldi than its neighborsNov 20 2014, 12:04 ET | By:Douglas W. House, SA News Editor France's hard line negotiations with Gilead Sciences (GILD -0.1%) over Sovaldi (sofosbuvir) pricing paid off. The agreed-upon price per box will be 13,667 Euros which is 5,...
Man I'm in a fog today. I forgot my ribavarin and sovaldi at 7 am. I take my second dose of ribv at 7pm. Since I forgot this mourning do I need to take both now? -- Edited by Ivery on Tuesday 9th of August 2016 08:00:14 PM
hi all .havant been on line for awhile.i got rid or the virus 18months ago.my liver was to badly damaged and i went on transplant list 2 months ago.amazingly i got the phone call two and a half wks ago that they had a liver for me.im now bk home recovering from op.at last after 9yrs of tx i am finally free to ho...
Hi-I am Hep c 2b -found out after 9/11/2001 when I donated blood. My ALT and AST are high I just got Fibroscan Compensated cirrhosis. I do not understand if Epclusa is highly tolerated without side effects and all genotypes -why it is not available. Also see that there are people taking it maybe trials?...
Hi gang ... I also just wanted to mention that I am currently on Day 48 of treatment (I know right?!) and I haven't been scheduled for any blood tests yet! I'm feeling a little worried as I notice you all having periodic blood tests. So I will be calling my GE tomorrow to ask him about this. I only ask as I a...
Just got "The Phone Call" from the pharmacy this morning ... ... I've been Approved for Sovaldi - Ribavirin and it will be here tomorrow ... *** Hark ... The swordsmith has finished my new sword and is sending it forthwith, via royal courier.... YaHoooo!! Ladies and Gentlemen, "Let...
I will arive @ my destination in one hour. It's been a very smooth ride for me. Thanks to all the support on the train. It was all of you who who makes the ride go fast and easily. Go tomorrow for labs. Mike
The current AASLD summary of recommendations for patients with decompensated cirrhosis:UNIQUE PATIENT POPULATIONS: PATIENTS WITH DECOMPENSATED CIRRHOSIS
Hi! I'm on my first week of Harvoni. So thankful i got insurance approval & copay assistance from Gilead!! I experienced the expected increased headaches and fatigue. Having a tough time - but of course, if I stop & make myself compare it to IFN, it's a "walk in the park." I took 1/2 Advil or 1/2...
I've noticed a lot of people here say they've given up drinking totally after they've completed their treatment. Is it bad to have a couple after work on a Friday evening? is there any evidence that drinking could wake up the virus if it's maybe undetectable but really still lurking? I wouldn't even t...
hello newly diagnosed at the beginning of July and still don't know my genotype yet. Initial viral load was 10 million going up to 12m on the 2nd test. The problem is the ALT reading. results of 4 tests to date are; 1st test - 153 2nd test - 93 3rd test - 1000+ 4th test - 1300+ Since diagnosis i haven't been d...
European Commission approves Zepatier for HCV genotypes 1, 4 August 1, 2016 Merck announced the European Commission granted marketing authorization for Zepatier to treat adult patients with chronic hepatitis C virus genotype 1 and 4 infection, with or without ribavirin, according to a comp...
My insurance only approved 8 wks of Harvoni claiming that I had not been on peginterferon plus ribavirin... They site "Ellen Guthrie Internal Medicine" as their source it seems. Anyone know what that is? 1) I had failed daily interferon with ribavirin but since I don't think my first doc that wrote th...
I thought I'd post some good news... I'm on my 11th day of Harvoni and when I walked on the treadmill tonight I experienced... drum roll... muscle strength!! I'm so excited & hope it has to do with Harvoni arresting some of my HCV enabling my liver to handle glycogen stores better for my muscles. Do y...
So, I'm SVR, ended treatment July 2014. In March 2014 when I was diagnosed my platelets were 77, stayed in the 60's for the past 2 years, but according to test results yesterday they were at 59. I see my hepatologist next Thursday and will talk to her about this, but I have to admit I'm feeling a little an...
hay there hope all are doing good, been a while and yup still single, still have two dogs but they are near their ends getting up there, this is first summer that got almost all stregth back, t
Hello Brothers and Sisters on the Hep C Discussion Forum. I wanted to report some rather great news. I checked my email from my Gastroentrologist's Nurse who reported I am undetected for the HCV at present time. I cannot tell you in words how I feel about this, but safe to say, I'm pretty much in awe ab...
Gossipy stuff / Marketing type interview ...GILD's plans for its HCV treatments: clear and conciseThe company's EVP and CSO, Norbert Bischofberger, presented last week at a Goldman Sachs (NYSE:GS) conference. One of his comments about GILD's HCV plans was quite revealing. He said:That is the...
Well yesterday I had my lab work done and got some partial results that make me feel positive. It will take at least 2 weeks to know my C and B Status but my general numbers are good. I have referenced my last two draws as well. EOT 5/2/16 ALT 35/ AST/25 ALP 68 EOT +5 6/7/16 ALT 28/AST/21 ALP...
Hi Everyone, The moment I've been dreading all month is close at hand - my endoscopy is scheduled for Wednesday morning. Please keep me in your thoughts and prayers - I just want it to be done with the least amount of discomfort and I really hope he doesn't find any problems. I wish my partner was here to go...
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