Things can interfere with absorption of DAA's. As rare as this occurrence may be, it is possible to absorb and accumulate too much, or, to not absorb enough of a DAA - so always read the monograph that comes with your DAA, and take your DAA as directed. In this below, I only concentrate mostly on how lower...
Hi everyone I don't come on here much because I have cirrhosis n some other deceases n I'm pretty tired most of the time, but I have another question. Has anyone experienced shingles? I've had herpes of some kind for 30 or so years, I usually get outbreaks on my upper leg, which has happened twice since...
Hey there old friends! I think of you often and figured I would just drop in and tell you all that! It's hard to believe it's been almost 4 years since I treated - crazy how fast time goes. Interestingly my doctor didn't test me this past May like he had the 2 years prior. I was tempted to ask for the test any...
Seems I am always doing something or sleeping...tired all the time. Going to Florida on Thanksgiving with grandkids. Trying to accomplish all the stuff I want to do before I go on the call list. Go in next week for a follow up MRI on the ablation and take a look at the two tumors. I think I have all my pre-tra...
About GT3's and our big ole fatty livers - sometimes size does matter!Now, I'm not necessarily talking about having an enlarged, inflamed liver, or a big ole fatty liver, these are never wanted things, just like having the HCV that may have caused same, is an unwanted thing, but rather I speak of big vi...
Well, Day-4 of taking the medication, so far no side effects and I'm not looking too hard to find any or imagine things that are not there. Although, in the past I have had 2 herniated disks in my lower back and it never really laid me out on my back. Once in a while I get stiffness in my lower back and have diff...
Clinical trial using Zepatier post heart transplant for patients receiving an organ from a Hep C positive donor. Recruiting trial participants.... Clinical Trial Info
Finally, after a month of delays and multiple Lab-Jabbings, the SS Epclusa is sailing in to my dock. Got this from HMO: _____ Greetings-I have ordered the Epclusa. Please contact me on Thursday if you have not heard back from me.NameOfPharm NPGastroenterology _____________ Now that is More Like It...
Hi Everyone, A friend in Alberta Canada has hep c, stage 2 fibrosis, and has been told by her doctor that AAHB (Alberta Adult Health Benefits) will not cover treatment for her. The doctor added that she would have to pay the 60k out of pocket, which she cannot afford. She is not on social assistance (welf...
Hello everyone Im new to this kind of thing but thought i would give it a try guess will start by giving a little background my wife and I are both hep C positive she has known about hers for about 15 years or so and when we first met and got together in 2013 she was straight out and honost with me and told me abou...
Tig found and posted this very interesting one - it's aptly under "clinical trials", but I don't want to loose track of this new NS5B, so borrowed Tig's find to be over here as well, so it can be seen as new "news" as well! Hope that's OK Tig. Janssen 2a trial
Dr. Feld's comments: about re-treatment, with Mavyret (glec/pib) versus Vosevi (sof/vel/vox) - similar to info found about re-treatment in the larger link (2017 Resource - Treatment Options ) and also covered in (2017 Resource - AASLD HCV Treatment Guidelines) - P. 38 of 247 - click on "re-treat...
News about Abby's Pan 8 week Glec (NS3/4A) and Pib (NS5A). No SOF. Especially intersting for those with compromized renal function, TN/TE/cirrhotics. They are stiving for shorter treatment times for these Pans. FDA grants priority review for AbbVie's pan-genotypic HCV regimen - February 3, 2...
Hm, we have entered into this topic before ... what about those of us who, out of medical necessity and via deemed "best practices" of the times, received not transfusions per say, but various forms of "immunoglobulins" , see (U.K. Tainted Blood Inquiry), see (Viet Nam era veterans/ They gave us t...
Just thought I'd share my encouraging news that 2 years on from successful treatment I had a fibroscan today... And I am now 9.2 down from 14.2 4 years ago. Not sure what to read into this but its much better than the news of old when every trip to the hospital would end in bad news! -- Edited by Midnight on Mo...
From Clinical Care Options - Clinical Thoughts TMFrom Clinical Care Options TM - Clinical Thoughts How New Data From the 2017 DC Hepatology Meeting Shed Light on the Clinical Benefits of HCV DAAsJordan J. Feld, MD, MPH - 11/14/2017More from this authorFor the first time in several years, we di...
Here is a series of articles about drug costs, HCV or otherwise - low cost deals, generics, name brands, availabilty and the powers that be - what's wrong with this picture?HCV treatments valued under $100 per patientHelio - December 12, 2016Researchers estimated that a generic direct-acting an...
hm, in this one they should have devoted a few more words about how "kinetic modeling" is not only potentially "cost-saving", (by allowing a 12 week course to be a shortened), but that another benefit of "kinetic modeling calculations" is justifying and providing the patient a possibly more ex...
This company has recently been promoting it's "product" as being FDA approved - their developed "method", their "product" (a sort of "scan/multi-level assessment/analysis") is being touted as a better, fuller, more informative way to assess hepatic "function", than other assesment methods....
hm, hope this graph is not too small to read - I could not seem to get it to enlarge. One of the abstracts (number 142) that was presented at the recent 2017 Liver Meeting, contained a simlar graph to the one below - it highlights the findings of G. Ioannou's (and co-authors) work (titled below). I had to so...
Hello I started Zepatier three weeks ago after being diagnosed with HCV 1a, I was quite nervous about starting treatment as i was unsure how it was going to affect me after hearing about the possible side effects. First week - Feeling positive - i exercised for 30 - 45 minutes daily, i had horrid stoma...
Hi everyone, Tig you had asked me awhile back what meds I was on in the clinical trial I was in last year. And I didn't know. Well I found my card that they gave me with the information on it!! The product numbers are MK3682 and MK8408. It also says protocol number MK3682-035. If that means anything. Do you...
Hi everyone - I've been looking round this forum for a while and found so much humour, mutual support and useful information that I thought it would be good to join instead of lurking on the edges! I am a 52 year old mum of two grown up boys, amicably divorced from their dad and have been happily settled wit...
I'm so afraid I have a fibrosis score of f3 and a viral load of 1,600,000 and starting to get ascites. In the process of getting approved for treatment. Am I to late will my ascites improve and my belly go down? These doctors won't be straight up with me.
Looks like Merck is going after different markets and dropping out of the HCV drug business. Zepatier is their last. Not a bad finish! It has cured a lot of people. Merck‘s Out
This had come up quite a times before in conversations, consideration of renal function while on DAA's, how to save work for the kidneys if they are not functioning up to par before you start DAA's. Zep has been highlighted, but we had one member here (in what seemed unusual, at first, at the time) who ha...
Commonly called a fibroscan (or a TE) - test which people have to derive an "Fscore" from. A non-invasive scanning method to determine levels of liver stiffness/fibrosis (and other parameters). Measurements of your liver elasticity/stiffness are obtained, expressed in kilopascals (kPa's) wh...
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