Clinical trial using Zepatier post heart transplant for patients receiving an organ from a Hep C positive donor. Recruiting trial participants.... Clinical Trial Info
Finally, after a month of delays and multiple Lab-Jabbings, the SS Epclusa is sailing in to my dock. Got this from HMO: _____ Greetings-I have ordered the Epclusa. Please contact me on Thursday if you have not heard back from me.NameOfPharm NPGastroenterology _____________ Now that is More Like It...
Hi Everyone, A friend in Alberta Canada has hep c, stage 2 fibrosis, and has been told by her doctor that AAHB (Alberta Adult Health Benefits) will not cover treatment for her. The doctor added that she would have to pay the 60k out of pocket, which she cannot afford. She is not on social assistance (welf...
Hello everyone Im new to this kind of thing but thought i would give it a try guess will start by giving a little background my wife and I are both hep C positive she has known about hers for about 15 years or so and when we first met and got together in 2013 she was straight out and honost with me and told me abou...
Tig found and posted this very interesting one - it's aptly under "clinical trials", but I don't want to loose track of this new NS5B, so borrowed Tig's find to be over here as well, so it can be seen as new "news" as well! Hope that's OK Tig. Janssen 2a trial
Dr. Feld's comments: about re-treatment, with Mavyret (glec/pib) versus Vosevi (sof/vel/vox) - similar to info found about re-treatment in the larger link (2017 Resource - Treatment Options ) and also covered in (2017 Resource - AASLD HCV Treatment Guidelines) - P. 38 of 247 - click on "re-treat...
News about Abby's Pan 8 week Glec (NS3/4A) and Pib (NS5A). No SOF. Especially intersting for those with compromized renal function, TN/TE/cirrhotics. They are stiving for shorter treatment times for these Pans. FDA grants priority review for AbbVie's pan-genotypic HCV regimen - February 3, 2...
Hm, we have entered into this topic before ... what about those of us who, out of medical necessity and via deemed "best practices" of the times, received not transfusions per say, but various forms of "immunoglobulins" , see (U.K. Tainted Blood Inquiry), see (Viet Nam era veterans/ They gave us t...
Just thought I'd share my encouraging news that 2 years on from successful treatment I had a fibroscan today... And I am now 9.2 down from 14.2 4 years ago. Not sure what to read into this but its much better than the news of old when every trip to the hospital would end in bad news! -- Edited by Midnight on Mo...
From Clinical Care Options - Clinical Thoughts TMFrom Clinical Care Options TM - Clinical Thoughts How New Data From the 2017 DC Hepatology Meeting Shed Light on the Clinical Benefits of HCV DAAsJordan J. Feld, MD, MPH - 11/14/2017More from this authorFor the first time in several years, we di...
Here is a series of articles about drug costs, HCV or otherwise - low cost deals, generics, name brands, availabilty and the powers that be - what's wrong with this picture?HCV treatments valued under $100 per patientHelio - December 12, 2016Researchers estimated that a generic direct-acting an...
hm, in this one they should have devoted a few more words about how "kinetic modeling" is not only potentially "cost-saving", (by allowing a 12 week course to be a shortened), but that another benefit of "kinetic modeling calculations" is justifying and providing the patient a possibly more ex...
This company has recently been promoting it's "product" as being FDA approved - their developed "method", their "product" (a sort of "scan/multi-level assessment/analysis") is being touted as a better, fuller, more informative way to assess hepatic "function", than other assesment methods....
hm, hope this graph is not too small to read - I could not seem to get it to enlarge. One of the abstracts (number 142) that was presented at the recent 2017 Liver Meeting, contained a simlar graph to the one below - it highlights the findings of G. Ioannou's (and co-authors) work (titled below). I had to so...
Hello I started Zepatier three weeks ago after being diagnosed with HCV 1a, I was quite nervous about starting treatment as i was unsure how it was going to affect me after hearing about the possible side effects. First week - Feeling positive - i exercised for 30 - 45 minutes daily, i had horrid stoma...
Hi everyone, Tig you had asked me awhile back what meds I was on in the clinical trial I was in last year. And I didn't know. Well I found my card that they gave me with the information on it!! The product numbers are MK3682 and MK8408. It also says protocol number MK3682-035. If that means anything. Do you...
Hi everyone - I've been looking round this forum for a while and found so much humour, mutual support and useful information that I thought it would be good to join instead of lurking on the edges! I am a 52 year old mum of two grown up boys, amicably divorced from their dad and have been happily settled wit...
I'm so afraid I have a fibrosis score of f3 and a viral load of 1,600,000 and starting to get ascites. In the process of getting approved for treatment. Am I to late will my ascites improve and my belly go down? These doctors won't be straight up with me.
Looks like Merck is going after different markets and dropping out of the HCV drug business. Zepatier is their last. Not a bad finish! It has cured a lot of people. Merck‘s Out
This had come up quite a times before in conversations, consideration of renal function while on DAA's, how to save work for the kidneys if they are not functioning up to par before you start DAA's. Zep has been highlighted, but we had one member here (in what seemed unusual, at first, at the time) who ha...
Commonly called a fibroscan (or a TE) - test which people have to derive an "Fscore" from. A non-invasive scanning method to determine levels of liver stiffness/fibrosis (and other parameters). Measurements of your liver elasticity/stiffness are obtained, expressed in kilopascals (kPa's) wh...
I went for my yearly bloods and ultrasound. The ultra sound came back with a dilated common bile duct. ( think I remember it always being like that) My hepc Doctor wanted a mri. All came back normal. I had all the blood work but before I went back he added another viral load test even though the one I had cam...
Being that I was a longstanding GT3a, with a prior abdominal ultrasound showing "steatosis" (fatty liver), and a "FibroScan" showing F4 (12.6 kPa) that provided no CAP measurement (which would be an indicator of the degree of liver fat content) I have a vested interest in the accuracy in assessing t...
Nonprofit challenges Gilead's patents on sofosbuvir October 27, 2017 - HelioInitiative for Medicines, Access & Knowledge - a U.S.-based nonprofit also known as I-MAK - filed a set of patent challenges against sofosbuvir, according to a press release from the organization. According to...
Lasker Award winner Michael Sofia created a pill to fight an incurable virus. Now he is setting his sights on another · By Dina Fine Maron on September 13, 2016 - Scientific America Inventor of Hepatitis C Wins a Major Prize -- and Turns to the Next Battle··· ...
About "Type" (IL28B) it still does matterSize (and "type") still does matter (somewhat) at least when we are talking about whether you are a CC, CT, CG, GG or a TT "type". Size? - high viral loads remain worthy of consideration when it comes to simply how potentially infective you might be (one just pla...
If you would like to educate yourself or have something to share with others, this organization has an informative website that will help. HepCHope Official Site
THIS FORUM, IT'S OWNERS, ADMINISTRATORS, MODERATORS AND MEMBERS DO NOT AT ANY TIME GIVE MEDICAL ADVICE AND IN ALL CASES REFER ANYONE HERE TO SEEK APPROPRIATE MEDICAL ADVICE FROM THEIR DOCTOR.
